
Panama Vacations & Trips
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Top destinations in Panama

Panama City

El Valle de Anton
Panama Vacation
While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.
Panama Hotel + Flights
Expedia has 3,139 hotels available here starting at NT$3,772 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Vacation Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavors like ceviche?
Your Panama Vacation Itinerary
Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colorful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.
Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.
Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.
Panama Information
Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.
If you’ll be spending most of your time in the nation’s capital, check out our Panama City Vacation PackagesOpens in a new window.
Want to really experience the carefree vibe of this Latin American gem? Book one of our Panama All Inclusive Resorts and say adios to vacation planning stress.
Panama Hotel Deals

Reviewed on 2025/4/22

Reviewed on 2025/4/22

Reviewed on 2025/4/22
Frequently asked questions
Discover the most popular places to visit in Panama

Miraflores Locks
Learn about the local history of Ancon with a stop at Miraflores Locks. Visit the shops and casinos in this vibrant area.
Colon Free Zone
During your trip to Colon, you can search for that perfect souvenir at Colon Free Zone.