A tropical island with palm trees and a clear blue sky.

Vacation Rentals in Panama

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Our top choices for Panama vacation rentals

A modern hotel lobby with a marble staircase, seating areas, and a large mirror reflecting the space.

1. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (589 reviews)
"Good stay here. Breakfast buffet was limited but good. Staff very friendly and helpful."
United States
Nalisa
The price is NT$2,953
NT$3,248 total
includes taxes & fees
Oct 12 - Oct 13
Torres de Alba Hotel & Suites
A rooftop pool with lounge chairs and a cityscape view.

2. Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (774 reviews)
"The staff were very friendly and made my birthday trip so special! Top-tier experience"
United States
Bruce
The price is NT$3,772
NT$4,149 total
includes taxes & fees
Oct 30 - Oct 31
Marriott Executive Apartments Panama City, Finisterre
A rooftop pool with a city view, lounge chairs, and a clear sky.

3. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (396 reviews)
"Nice place good location"
United States
Rame
The price is NT$3,065
NT$3,582 total
includes taxes & fees
Oct 29 - Oct 30
Corporate Stays Arcadia | Executive Furnished Apartments
A rooftop pool area with lounge chairs and a table, overlooking a cityscape with tall buildings.

4. Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
8.0 out of 10, Very good, (393 reviews)
"Great stay!!!!"
United States
fitz
The price is NT$1,263
NT$4,882 total
includes taxes & fees
Oct 12 - Oct 13
Boutique Apartments Panama
A multi-story building with balconies, large windows, and a clear blue sky.

5. Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (206 reviews)
"Great food and location"
United States
James
The price is NT$4,042
NT$5,085 total
includes taxes & fees
Oct 28 - Oct 29
Las Clementinas
A modern hotel room with a large bed, a glass coffee table, a sofa, a kitchen area with a bar, and a view of the outdoors.

6. El Cielo by Villa Alejandro

El Cielo by Villa Alejandro
3.5 star property
Boquete
9.4 out of 10, Exceptional, (125 reviews)
"Very nice place Very clean"
United States
Erez
The price is NT$1,959
NT$2,155 total
includes taxes & fees
Oct 12 - Oct 13
El Cielo by Villa Alejandro
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

7. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (111 reviews)
"It is a new place, an apartment was in pristine condition. The building is 2 blocks away from the old town."
United States
Arshak Andrew
The price is NT$2,672
NT$3,897 total
includes taxes & fees
Oct 12 - Oct 13
Casco View Life Residences
A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

8. La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (212 reviews)
"Location in old town, across from Plaza Simon Bolivar, is the perfect place to venture around old town and the new city. Great restaurants and shops within easy walking distance. I relied on recommendations from the staff for a couple of things and their selections exceeded my expectations. Highly recommend staying if visiting Panama City."
United States
David
The price is NT$5,028
NT$5,531 total
includes taxes & fees
Oct 13 - Oct 14
La Isabela Suites
A modern hotel entrance with a well-lit facade, a prominent sign, and a landscaped garden area.

9. Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.0 out of 10, Very good, (142 reviews)
"It was a very beautiful property and prime location! All around experience was great!"
United States
Michelle
The price is NT$1,523
NT$6,114 total
includes taxes & fees
Nov 1 - Nov 2
Yoo Panamá by Boutique Apartments
A rooftop infinity pool with a city skyline view, lounge chairs, and palm trees.

10. Apartments at The Sands – Ocean View Panama City

Apartments at The Sands – Ocean View Panama City
3.5 star property
Calidonia
7.8 out of 10, Good, (29 reviews)
"Check in at 3 was a bit difficult, but the assistance staff were wonderful. Would absolutely stay again."
United States
Thomas M
The price is NT$2,155
NT$2,371 total
includes taxes & fees
Oct 12 - Oct 13
Apartments at The Sands – Ocean View Panama City
A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

11. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is NT$4,370
NT$4,807 total
includes taxes & fees
Oct 14 - Oct 15
La Résidence Panamá
A rooftop pool with lounge chairs and a bar, overlooking a city skyline at dusk.

12. Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
3.5 star property
Bella Vista
8.4 out of 10, Very good, (6 reviews)
"Good price for the location."
United States
Mark
The price is NT$3,957
NT$4,352 total
includes taxes & fees
Oct 15 - Oct 16
Yoo Panama Luxury Ocean View Apartment
A wooden staircase leading to a covered outdoor area with a view of a lush garden and a distant building.

13. Downtown Suites

Downtown Suites
3.0 star property
El Tropezón
9.0 out of 10, Wonderful, (114 reviews)
"The suite was conveniently located and very comfortable. Loved the back patio overlooking the garden. The best part was the friendly and extremely helpful staff. Definitely would stay again"
United States
Patricia
The price is NT$1,983
NT$2,181 total
includes taxes & fees
Oct 22 - Oct 23
Downtown Suites
A modern outdoor swimming pool with a clear view of a tall building in the background.

14. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (38 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
The price is NT$4,942
NT$5,436 total
includes taxes & fees
Nov 9 - Nov 10
Dovle Residences by HMS-Preferred Member
A garden with a stone bridge, a small waterfall, and various plants and flowers.

15. Rio Verde by Villa Alejandro

Rio Verde by Villa Alejandro
2.5 star property
Los Naranjos
9.4 out of 10, Exceptional, (117 reviews)
"Loved the grounds and the hot tub room was awesome!"
United States
John
The price is NT$1,796
NT$2,643 total
includes taxes & fees
Oct 12 - Oct 13
Rio Verde by Villa Alejandro
An outdoor seating area with tables and chairs, a tree with pink blossoms, and a cityscape view.

16. Modern Design Apartments near Sortis

Modern Design Apartments near Sortis
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (11 reviews)
"This property was much more than I expected, room and property was clean, lots of restaurants around the area, easy to get around, will certainly be back at this property"
United States
Kareem
The price is NT$2,010
NT$2,211 total
includes taxes & fees
Oct 21 - Oct 22
Modern Design Apartments near Sortis
A modern outdoor deck with a sectional sofa, a coffee table, and a fire pit.

17. Natura Lodge by Villa Alejandro

Natura Lodge by Villa Alejandro
Bajo Boquete
The price is NT$1,975
NT$2,780 total
includes taxes & fees
Oct 25 - Oct 26
Natura Lodge by Villa Alejandro
An aerial view of a residential area with two swimming pools, surrounded by houses with sloped roofs.

18. Villas The Tides by Playa Caracol Resort

Villas The Tides by Playa Caracol Resort
3.5 star property
Punta Chame
9.0 out of 10, Wonderful, (9 reviews)
"Loved it! Super comfortable, near the beach everything clean"
United States
Tayna
The price is NT$2,043
NT$2,247 total
includes taxes & fees
Oct 13 - Oct 14
Villas The Tides by Playa Caracol Resort
An outdoor dining area with a round table and white chairs, surrounded by orange walls and a blue ceiling.

19. Surfari Bocas

Surfari Bocas
2.5 star property
Bocas del Toro
9.0 out of 10, Wonderful, (69 reviews)
"Lost our key partying about in Bocas town, came back to the hotel at 3am and the owner (great guy) let us back in!! Our savior and the accommodations (AC in particular) were very nice. Would 100% stay here again."
United States
Carter
The price is NT$891
NT$980 total
includes taxes & fees
Oct 12 - Oct 13
Surfari Bocas
A modern living room with a sofa, coffee table, and chairs, a dining table with water bottles, and large windows with a city view.

20. Mini Design By Wynwood House

Mini Design By Wynwood House
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (4 reviews)
"The pool is amazing. I love that is it long enough to do laps if one would like a workout."
United States
Monica
The price is NT$3,477
NT$4,878 total
includes taxes & fees
Oct 12 - Oct 13
Mini Design By Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Panama Hotel Reviews

Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"The spa was under renovation."
Ryan 7-night trip
Posted 3 hours ago
Decapolis Hotel Panama City

Find out more about Panama

Vacation Apartments in Panama

Search for Vacation rentals in Panama on Expedia.! You can easily find your home rentals, villas, Vacation apartments in Panama using one of the methods below:

  • View our selection of featured Vacation rentals in Panama
  • Use the map to find apartments and other Vacation homes in the Panama neighbourhood you prefer
  • Enter your travel dates to view the best deals on Vacation rentals in Panama while they last

Look no further and take a look at our great range of rental properties in Panama!

Explore a world of travel with Expedia