Find Resorts & Hotels with Spas in Otay Mesa, CA

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Check availability on Otay Mesa Resorts & Hotels with Spas

Tonight
Nov 25 - Nov 26
Tomorrow
Nov 26 - Nov 27
This weekend
Nov 28 - Nov 30
Next weekend
Dec 5 - Dec 7

Top Otay Mesa Resorts & Hotels with Spas

Fitness studio
Sycuan Casino Resort

Sycuan Casino Resort

4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1622)
"Nice hotel and friendly staff. Will definitely stay again ."
United States
Lorna
Sycuan Casino Resort
Facials, 2 treatment rooms, massages
The Westin San Diego Bayview

The Westin San Diego Bayview

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1035)
"Spacious rooms , great staff "
United States
Jessica
The price is NT$3,717
NT$5,221 total
includes taxes & fees
Dec 19 - Dec 20
The Westin San Diego Bayview
Body treatments, aromatherapy, body wraps, body scrubs, facials
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1824)
"Great location , beautiful restaurant and nice grounds"
United States
Dawn
The price is NT$2,545
NT$4,494 total
includes taxes & fees
Dec 22 - Dec 23
Hilton San Diego Bayfront
Exterior
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1567)
"Loved our stay "
United States
Jeremy
The price is NT$4,686
NT$7,050 total
includes taxes & fees
Nov 26 - Nov 27
Hyatt Regency Mission Bay Spa and Marina
Premier Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes
Handlery Hotel

Handlery Hotel

3.5 star property
Mission Valley
8.2 out of 10, Very Good, (2217)
"Staff was amazing and very accommodating. Always recommended staying here. "
United States
Taja
The price is NT$2,400
NT$2,758 total
includes taxes & fees
Dec 7 - Dec 8
Handlery Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
National City
9.2 out of 10, Wonderful, (3451)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is NT$3,743
NT$4,124 total
includes taxes & fees
Nov 30 - Dec 1
Best Western Plus Marina Gateway Hotel
Couples treatment rooms, sauna, hot tub, steam room, body treatments
Loews Coronado Bay Resort

Loews Coronado Bay Resort

4.0 star property
Silver Strand
8.8 out of 10, Excellent, (1066)
"My stay was wonderful! "
United States
Jeanine
The price is NT$5,630
NT$7,776 total
includes taxes & fees
Dec 14 - Dec 15
Loews Coronado Bay Resort
Hot stone massages, prenatal massages, sports massages, body scrubs
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is NT$5,257
NT$7,460 total
includes taxes & fees
Dec 16 - Dec 17
San Diego Mission Bay Resort
Reception
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

3.0 star property
Point Loma
8.8 out of 10, Excellent, (1557)
"Nice hotel "
United States
Anthony
The price is NT$4,123
NT$4,739 total
includes taxes & fees
Dec 15 - Dec 16
Best Western Plus Island Palms Hotel & Marina
Couples treatment rooms, body treatments, hot stone massages
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2960)
"Great stay"
United States
Songkwon
The price is NT$5,062
NT$5,819 total
includes taxes & fees
Dec 8 - Dec 9
Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Otay Mesa Hotel Reviews

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

10/10 Excellent
"The place was clean and the staff friendly and took good care of me."
Andrea 1-night trip
Posted 16 hours ago
Courtyard by Marriott San Diego Downtown Little Italy

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Frequently asked questions

Looking for a spa hotel in Otay Mesa?
Treat yourself to some pampering and book a hotel with a spa. Check out the theater scene and shopping in Otay Mesa—your day trip starts here. Discover the beaches and many popular restaurants during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Otay Mesa?
Enjoy Otay Mesa with a stop at San Diego Zoo, San Ysidro Border Crossing, and Petco Park. If you have spare time during your trip, you might want to make a stop at Rosarito Beach and Port of San Diego.
What is a Otay Mesa spa hotel?
Spa hotels in Otay Mesa provide lodging and have a full on-site spa which offers services like massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.