Find Hotels with smoking rooms in Otay Mesa, CA
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Our top choices for Otay Mesa hotels with designated smoking areas
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.0 out of 10, Very Good, (1574)
"Great place to stay. Really clean and helpful staff "
Zulma
The price is NT$3,741
NT$4,255 total
includes taxes & fees
Jan 11 - 2026/1/12
8.4 out of 10, Very Good, (1318)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
Haley
The price is NT$4,313
NT$6,619 total
includes taxes & fees
Jan 12 - 2026/1/13
Hampton Inn & Suites by Hilton San Diego SeaWorld
Hampton Inn & Suites by Hilton San Diego SeaWorldPoint Loma
9.2 out of 10, Wonderful, (452)
"Clean room, helpful staff, convenient location "
David
The price is NT$3,714
NT$4,269 total
includes taxes & fees
Jan 5 - 2026/1/6
8.8 out of 10, Excellent, (1065)
"Clean room, gorgeous grounds, very friendly staff "
Taryn
The price is NT$6,255
NT$8,478 total
includes taxes & fees
Jan 3 - 2026/1/4
7.4 out of 10, Good, (1479)
"Parking was easy."
Erica
The price is NT$2,055
NT$2,266 total
includes taxes & fees
Dec 30 - Dec 31
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp QuarterDowntown San Diego
9.0 out of 10, Wonderful, (1243)
"Clean, courteous staff, good location. "
Carla
The price is NT$3,112
NT$3,608 total
includes taxes & fees
Dec 30 - Dec 31
7.6 out of 10, Good, (1002)
"Rooms were very clean and efficient "
Leslie
The price is NT$2,378
NT$2,621 total
includes taxes & fees
Jan 1 - 2026/1/2
9.2 out of 10, Wonderful, (3232)
"Great stay and location!"
Jason
The price is NT$3,367
NT$3,870 total
includes taxes & fees
Jan 4 - 2026/1/5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Otay Mesa Hotel Reviews
The DEXTRO Little Italy, BW Premier Collection
10/10 Excellent
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