An ancient stone corridor with arches, potted plants, and a dome structure in the background.

Find Resorts & Hotels with Spas in Mission, TX

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Mission Resorts & Hotels with Spas

Next weekend
In two weeks

Our top choices for Mission hotels with a spa

1. La Quinta Inn & Suites by Wyndham Mission at West McAllen

La Quinta Inn & Suites by Wyndham Mission at West McAllen
3.0 star property
Mission
8.6 out of 10, Excellent, (1,047 reviews)
"Had a great stay, will be booking again if in the area."
United States
James
The price is NT$2,605
NT$2,944 total
includes taxes & fees
Nov 13 - Nov 14
La Quinta Inn & Suites by Wyndham Mission at West McAllen

2. SureStay Hotel By Best Western Mission

SureStay Hotel By Best Western Mission
2.5 star property
Mission
8.2 out of 10, Very good, (901 reviews)
"Great stay"
United States
Angelica
The price is NT$1,467
NT$1,658 total
includes taxes & fees
Nov 8 - Nov 9
SureStay Hotel By Best Western Mission

3. Motel 6 Mission, TX

Motel 6 Mission, TX
2.0 star property
Mission
8.8 out of 10, Excellent, (1,274 reviews)
"Excelente"
Mexico
Carlos
The price is NT$1,643
NT$1,856 total
includes taxes & fees
Nov 15 - Nov 16
Motel 6 Mission, TX

4. Hampton Inn & Suites Mission

Hampton Inn & Suites Mission
3.0 star property
Mission
9.4 out of 10, Exceptional, (61 reviews)
"Liked the location, rooms were clean and very friendly service."
United States
Ruben
The price is NT$2,914
NT$3,309 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn & Suites Mission

5. Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
2.5 star property
Mission
9.2 out of 10, Wonderful, (1,004 reviews)
"Clean, quiet rooms and friendly staff"
United States
Mekila
The price is NT$2,543
NT$2,873 total
includes taxes & fees
Nov 5 - Nov 6
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

6. avid hotel Mission East - McAllen Area by IHG

avid hotel Mission East - McAllen Area by IHG
2.0 star property
Mission
9.0 out of 10, Wonderful, (114 reviews)
"The room was very spacious and clean. The staff were extremely friendly. Lots of restaurants and shops nearby. The only downside was I had no chair in my room to sit on, only the bed. Very pleasant stay and affordable price. Would definitely recommend a stay at this hotel."
United States
Robert
The price is NT$2,282
NT$2,579 total
includes taxes & fees
Nov 8 - Nov 9
avid hotel Mission East - McAllen Area by IHG

7. The Bungalows on Shary, Mission-McAllen

The Bungalows on Shary, Mission-McAllen
2.5 star property
Mission
9.0 out of 10, Wonderful, (1,003 reviews)
"Such a beautiful location"
United States
anna
The price is NT$3,491
NT$3,945 total
includes taxes & fees
Nov 3 - Nov 4
The Bungalows on Shary, Mission-McAllen

8. Comfort Inn Mission - McAllen West

Comfort Inn Mission - McAllen West
2.5 star property
Mission
8.6 out of 10, Excellent, (416 reviews)
"Everything was great, couldn't have asked for better"
United States
GLORIA
The price is NT$2,328
NT$2,630 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn Mission - McAllen West

9. Candlewood Suites Mission East Mcallen Area by IHG

Candlewood Suites Mission East Mcallen Area by IHG
2.5 star property
Mission
9.0 out of 10, Wonderful, (34 reviews)
"The rooms were a great size with a small kitchenette and small refrigerator. The hotel was immaculate, the beds were very comfortable, and the water pressure was great with plenty of hotel water. The hotel is a little pricey since it is right next to the Mission Event Center but the location was great"
United States
Thomas
The price is NT$4,140
NT$4,678 total
includes taxes & fees
Nov 15 - Nov 16
Candlewood Suites Mission East Mcallen Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Mission

Top Mission Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Mission?
Forget the stress of everyday life and book yourself a lush spa hotel. Check out the entertainment choices and shopping in Mission—your day trip starts here. Enjoy the live music and many popular restaurants during your vacation. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in Mission?
Take in the sights and attractions that Mission offers with a visit to Rio Grande, Shary Municipal Golf Course, and Bentsen-Rio Grande Valley State Park. If you have a little extra time during your trip, you might want to make a stop at Anzalduas Park and Mission Historical Museum.
What is a Mission spa hotel?
Spa hotels in Mission provide lodging and have an on-site spa offering services like massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

Explore a world of travel with Expedia