Find hotels in Medicine Lake, Minneapolis - St. Paul

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Our top choices for Medicine Lake hotels

Holiday Inn Express & Suites Mall of America - MSP Airport by IHG

Holiday Inn Express & Suites Mall of America - MSP Airport by IHG
2.5 star property
19.9 km from Medicine Lake
9.0 out of 10, Wonderful, (2898)
"Great place to stay!!! "
United States
Tamera
The price is NT$2,640
NT$3,064 total
includes taxes & fees
Jan 1 - 2026/1/2
Holiday Inn Express & Suites Mall of America - MSP Airport by IHG

Hilton Garden Inn Minneapolis Airport Mall of America

Hilton Garden Inn Minneapolis Airport Mall of America
3.5 star property
20.3 km from Medicine Lake
8.4 out of 10, Very Good, (2192)
"Great staff great rooms "
United States
Mathew
The price is NT$2,282
NT$2,648 total
includes taxes & fees
Jan 25 - 2026/1/26
Hilton Garden Inn Minneapolis Airport Mall of America

Hilton Minneapolis

Hilton Minneapolis
4.0 star property
11.8 km from Medicine Lake
8.8 out of 10, Excellent, (1009)
"It was a nice stay "
Canada
Shannon
The price is NT$3,122
NT$3,654 total
includes taxes & fees
Jan 26 - 2026/1/27
Hilton Minneapolis

The Lofton Hotel, Tapestry Collection by Hilton

The Lofton Hotel, Tapestry Collection by Hilton
4.5 star property
11.6 km from Medicine Lake
9.4 out of 10, Exceptional, (1005)
"Friendly staff, comfortable beds, beautiful views, great location "
United States
Julia
The price is NT$3,606
NT$4,220 total
includes taxes & fees
Jan 9 - 2026/1/10
The Lofton Hotel, Tapestry Collection by Hilton

Hyatt Regency Bloomington - Minneapolis

Hyatt Regency Bloomington - Minneapolis
4.0 star property
21.9 km from Medicine Lake
9.0 out of 10, Wonderful, (2073)
"Clean room, great breakfast, convenient "
United States
Joanne
The price is NT$2,923
NT$3,392 total
includes taxes & fees
Jan 4 - 2026/1/5
Hyatt Regency Bloomington - Minneapolis

The Marquette Hotel, Curio Collection by Hilton

The Marquette Hotel, Curio Collection by Hilton
4.0 star property
11.9 km from Medicine Lake
9.4 out of 10, Exceptional, (1004)
"Clean, helpful staff and location. "
United States
Sheena Martina
The price is NT$3,364
NT$3,937 total
includes taxes & fees
Jan 6 - 2026/1/7
The Marquette Hotel, Curio Collection by Hilton

Hampton Inn & Suites Minneapolis / Downtown

Hampton Inn & Suites Minneapolis / Downtown
3.0 star property
11.5 km from Medicine Lake
9.4 out of 10, Exceptional, (1939)
"Courteous staff and great location. "
United States
Darren
The price is NT$2,396
NT$2,804 total
includes taxes & fees
Jan 5 - 2026/1/6
Hampton Inn & Suites Minneapolis / Downtown

Hampton Inn & Suites Minneapolis University Area

Hampton Inn & Suites Minneapolis University Area
2.5 star property
16.3 km from Medicine Lake
9.4 out of 10, Exceptional, (1004)
"Everything was very efficient at check in, nice place"
United States
Michael
The price is NT$2,396
NT$2,852 total
includes taxes & fees
Jan 6 - 2026/1/7
Hampton Inn & Suites Minneapolis University Area

Fairfield Inn & Suites by Marriott Minneapolis Shakopee

Fairfield Inn & Suites by Marriott Minneapolis Shakopee
2.5 star property
24.1 km from Medicine Lake
9.0 out of 10, Wonderful, (766)
"The desk clerk was very friendly, polite and responsive. Love staying here."
United States
Craig
The price is NT$2,659
NT$2,962 total
includes taxes & fees
Jan 1 - 2026/1/2
Fairfield Inn & Suites by Marriott Minneapolis Shakopee

Embassy Suites by Hilton Minneapolis Airport

Embassy Suites by Hilton Minneapolis Airport
4.0 star property
21.9 km from Medicine Lake
9.0 out of 10, Wonderful, (1870)
"Great place to stay!"
United States
Rhonda
The price is NT$3,268
NT$3,791 total
includes taxes & fees
Jan 11 - 2026/1/12
Embassy Suites by Hilton Minneapolis Airport

Hyatt Place Minneapolis Downtown

Hyatt Place Minneapolis Downtown
3.0 star property
12.4 km from Medicine Lake
8.4 out of 10, Very Good, (2074)
"excellent fast check in, room is great. Very nice hotel"
Canada
Rob
The price is NT$3,112
NT$3,642 total
includes taxes & fees
Jan 8 - 2026/1/9
Hyatt Place Minneapolis Downtown

The Royal Sonesta Minneapolis Downtown

The Royal Sonesta Minneapolis Downtown
4.5 star property
11.7 km from Medicine Lake
9.0 out of 10, Wonderful, (1782)
"Beautiful hotel, great staff! "
United States
Katie
The price is NT$3,475
NT$4,066 total
includes taxes & fees
Jan 16 - 2026/1/17
The Royal Sonesta Minneapolis Downtown

Sheraton Minneapolis Downtown Convention Center

Sheraton Minneapolis Downtown Convention Center
3.5 star property
11.6 km from Medicine Lake
8.8 out of 10, Excellent, (123)
"Very nice rooms and convenient location "
United States
Tiffany
The price is NT$3,426
NT$4,010 total
includes taxes & fees
Jan 1 - 2026/1/2
Sheraton Minneapolis Downtown Convention Center

Baymont by Wyndham Bloomington MSP Airport

Baymont by Wyndham Bloomington MSP Airport
2.5 star property
19.8 km from Medicine Lake
8.0 out of 10, Very Good, (2098)
"Great stay and great hotel!"
United States
Dillon
The price is NT$2,004
NT$2,245 total
includes taxes & fees
Jan 26 - 2026/1/27
Baymont by Wyndham Bloomington MSP Airport

The Westin Minneapolis

The Westin Minneapolis
4.0 star property
11.9 km from Medicine Lake
8.2 out of 10, Very Good, (1004)
"Always a great stay at the Westin! "
United States
gabby
The price is NT$3,426
NT$4,010 total
includes taxes & fees
Dec 30 - Dec 31
The Westin Minneapolis

Hyatt Regency Minneapolis

Hyatt Regency Minneapolis
4.0 star property
11.6 km from Medicine Lake
8.8 out of 10, Excellent, (1005)
"Everything excellent there. "
United States
Franklin
The price is NT$3,081
NT$3,751 total
includes taxes & fees
Jan 5 - 2026/1/6
Hyatt Regency Minneapolis

Hampton Inn by Hilton Minneapolis/Eagan

Hampton Inn by Hilton Minneapolis/Eagan
2.5 star property
26.7 km from Medicine Lake
8.8 out of 10, Excellent, (1008)
"Great staff…great place!"
United States
Mark
The price is NT$3,067
NT$3,409 total
includes taxes & fees
Jan 5 - 2026/1/6
Hampton Inn by Hilton Minneapolis/Eagan

Hampton Inn & Suites Downtown St. Paul

Hampton Inn & Suites Downtown St. Paul
2.5 star property
25.6 km from Medicine Lake
9.4 out of 10, Exceptional, (1037)
"Good Location to stay as always!"
United States
Josh
The price is NT$3,364
NT$3,932 total
includes taxes & fees
Jan 7 - 2026/1/8
Hampton Inn & Suites Downtown St. Paul

Fairfield Inn & Suites By Marriott Minneapolis Downtown

Fairfield Inn & Suites By Marriott Minneapolis Downtown
2.5 star property
11.3 km from Medicine Lake
9.0 out of 10, Wonderful, (1475)
"Friendly staff, nice room, comfy bed."
United States
david
The price is NT$2,703
NT$3,164 total
includes taxes & fees
Jan 5 - 2026/1/6
Fairfield Inn & Suites By Marriott Minneapolis Downtown

Hyatt House Mall Of America Msp Airport

Hyatt House Mall Of America Msp Airport
2.5 star property
22 km from Medicine Lake
8.6 out of 10, Excellent, (1721)
"Amazing rooms and top notch breakfast!! Will definitely stay again when in the area!!"
United States
Mariel
The price is NT$3,049
NT$3,538 total
includes taxes & fees
Jan 10 - 2026/1/11
Hyatt House Mall Of America Msp Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medicine Lake

Find the best Medicine Lake areas and neighborhoods for the activities you enjoy most.

Downtown Minneapolis

Known for its fantastic nightlife and popular shops, there's plenty to explore in Downtown Minneapolis. Check out top attractions like Nicollet Mall and Foshay Tower, and jump on the metro at Nicollet Mall Station or Warehouse - Hennepin Station to see more of the city.

Downtown St. Paul

Spend some time visiting places like Fitzgerald Theater while getting to know Downtown St. Paul, and be sure to check out the live music. You can hop aboard the metro at 10th Street Station or Central Station to see more of the area.

South Minneapolis

If you're spending time in South Minneapolis, check out sights like Parkway Theater or Lake Nokomis and hop on the metro to see more the city at 38th Street Station or 46th Street Station.

Downtown West

Heart of downtown Minneapolis, Downtown West boasts high-rise office buildings and notable landmarks like Foshay Tower and IDS Center. A bustling urban hub for business and architecture enthusiasts.

South Loop

While you're in South Loop, take in top sights like Mall of America or Sea Life Minnesota Aquarium, and hop on the metro to see more the city at 28th Avenue Station or Mall of America Station.

Top Medicine Lake Hotel Reviews

Find out more about Medicine Lake

Top reasons to visit Medicine Lake

  • Scenic Lake Views: Medicine Lake offers breathtaking views, perfect for relaxation and photography.
  • Outdoor Activities: Enjoy kayaking, fishing, and hiking in the surrounding parks and trails.
  • Romantic Getaways: The serene environment is ideal for couples looking to unwind together.
  • Local Culture: Explore charming neighborhoods filled with unique eateries and friendly atmospheres.
  • Diverse Accommodations: Choose from a range of lodging options, catering to every traveler's needs.

Find great hotels near Medicine Lake

Discover a range of hotel accommodations in Medicine Lake, Minnesota, perfect for your vacation needs. Whether you're seeking a business-friendly environment, a pet-friendly stay, or an LGBTQIA-friendly experience, you'll find options that cater to your preferences. Explore the best hotels in the area, including cozy hostels and budget-friendly choices, ensuring a comfortable and enjoyable visit to this charming lakeside destination.

  • Sheraton Minneapolis Downtown Convention Center: Embracing a welcoming atmosphere, the Sheraton Minneapolis Downtown Convention Center is a 3.5-star hotel perfect for LGBTQIA travelers and those seeking a pet-friendly experience. Located 11.3km from Medicine Lake, it provides a blend of comfort and convenience for business trips and leisure stays alike. The hotel features essential amenities including a business center and meeting rooms, while also catering to pet owners with its pet-friendly policies. Enjoy a stay that celebrates inclusivity and comfort in the heart of the city.
  • The Royal Sonesta Minneapolis Downtown: For those in pursuit of luxury, The Royal Sonesta Minneapolis Downtown is a 4.5-star hotel that offers an elegant urban experience. Situated 11.3km from Medicine Lake, this hotel is ideal for business travelers and luxury seekers alike, featuring upscale amenities and a prime city center location. Guests can indulge in fine dining, a state-of-the-art fitness center, and beautifully appointed rooms that seamlessly blend sophistication with comfort. Experience the vibrant pulse of Minneapolis while enjoying top-tier service and accommodations.
  • Ramada by Wyndham Minneapolis Golden Valley: The Ramada by Wyndham Minneapolis Golden Valley is a family-friendly 3.5-star hotel located 4.8km from Medicine Lake. This hotel is perfect for business travelers and families, offering thoughtful amenities such as free cribs and window guards for children. With its central location, guests can easily explore the city while enjoying the comfortable accommodations and modern facilities. The Ramada ensures a welcoming environment for families, making it a great choice for those traveling with kids.

Where to stay near Medicine Lake

Medicine Lake offers a delightful getaway with its beautiful lake and scenic parks perfect for outdoor adventures and romantic strolls. Explore nearby neighborhoods that boast a friendly atmosphere and a mix of urban charm and luxury. Uncover hidden gems like local eateries and picturesque walking trails. Whether you're picnicking by the shore or enjoying family-friendly activities, Medicine Lake promises an unforgettable experience filled with natural beauty and warm hospitality.

  • Minneapolis - St. Paul: The vibrant metropolitan area of Minneapolis - St. Paul surrounds Medicine Lake, offering a unique blend of urban culture and natural beauty. The region is known for its diverse attractions, catering to families, business travelers, and city explorers alike. Visitors can enjoy shopping at major malls, catching a game at a local sports stadium, or attending events at conference venues. The scenic lakes, including Medicine Lake, add a touch of tranquility amidst the bustling city life, making it an ideal destination for various activities throughout the year.
  • Minneapolis: Located a short distance from Medicine Lake, Minneapolis is a dynamic city that showcases a rich cultural scene and numerous recreational opportunities. Known for its family-friendly atmosphere and business hubs, Minneapolis attracts visitors year-round. Explore the extensive shopping centers, catch exciting sports events, or relax by the nearby lakes. The city hosts vibrant festivals in the summer, and with its iconic landmarks, Minneapolis serves as a perfect base for discovering the Twin Cities' charm.
  • Plymouth: As one of the cities that Medicine Lake calls home, Plymouth offers a welcoming suburban experience with a family-oriented vibe. This city features a variety of shopping options and entertainment venues, making it a great spot for visitors seeking leisure and fun. With its proximity to beautiful lakes and parks, outdoor enthusiasts will enjoy activities like hiking and boating. Plymouth is ideal for those wanting to experience a blend of suburban tranquility and easy access to urban amenities.

Things to do near Medicine Lake

Medicine Lake in Plymouth, Minnesota, is perfect for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can enjoy various activities, including shopping at local centers and exploring recreational areas. The scenic beauty of the lake enhances the experience, making it a memorable destination for relaxation and adventure. Whether you're looking to unwind or explore, Medicine Lake offers a delightful blend of nature and convenience.

Shopping

Experience shopping in Medicine Lake at Ridgedale Center, just 3.2km away, offering a vibrant mix of entertainment and family-friendly vibes. Head to Shops at West End, 6.4km away, for more shopping options, or visit Byerly's, located 9.7km from Medicine Lake for unique gifts and groceries.

Recreation

Target Field offers an exhilarating sports atmosphere, perfect for catching a baseball game. Nearby, the Fillmore Theater & Element by Westin provides vibrant entertainment with live music events. For outdoor enthusiasts, Brookview Golf Course features scenic fairways, ideal for a relaxing day of golfing amidst nature.

Adventure

Experience the thrills at Venetian Indoor Waterpark, featuring exciting slides and family-friendly attractions only 9.7km from Medicine Lake. For ice skating enthusiasts, the Plymouth Ice Center, located 4.8km away, offers a fun skating experience. Hike along the scenic Dakota Rail Regional Trail, situated 8.0km away, for stunning outdoor views.

Nightlife

Experience the vibrant nightlife at the Orpheum Theatre and State Theatre, both offering romantic entertainment and cultural vibes, just 11.3km away. For family fun, check out Sky Zone Indoor Trampoline Park, located 1.6km away, where adventure awaits for all ages.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Medicine Lake

To save money on your trip to Medicine Lake, consider visiting during the off-peak months of December to February when prices are lower. Aim to book your stay on a Monday for the best rates, while Saturdays tend to be more expensive. Use Expedia to find flexible booking options and package deals that bundle your hotel, flights, and activities for added savings. Additionally, explore free activities around the lake and utilize public transportation to minimize travel costs. Look for eco-certified accommodations to ensure a sustainable stay while keeping your budget in check.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Medicine Lake are December to February, where the prices are slightly lower. This is in comparison to June to August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Medicine Lake is Monday. The most expensive day to stay around Medicine Lake is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to customize your options based on your budget, desired location, and preferred hotel style. For instance, selecting the Eco-certified filter will showcase sustainable and eco-friendly accommodations currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay at Medicine Lake with your flights and activities through an Expedia package.

Find the best attractions near Medicine Lake

Medicine Lake in Plymouth, Minnesota, is perfect for outdoor and romantic getaways, offering beautiful scenery and a variety of attractions. Visitors can enjoy the serene lake, explore nearby urban parks, and immerse themselves in local culture. Notable points of interest include Medicine Lake East Glacier Park and Two Medicine Lake, ensuring a diverse experience that caters to outdoor enthusiasts and beach lovers alike.

  • Target Center: Experience the excitement at Target Center, home to thrilling sporting events and concerts. With a family-friendly atmosphere, this venue offers a diverse range of entertainment options, making it perfect for visitors of all ages.
  • Minneapolis Convention Center: A hub for conferences and events, the Minneapolis Convention Center boasts modern facilities and a professional vibe. It's an ideal place to explore new ideas, network, and experience the city's business culture, all while being close to various dining and entertainment options.
  • University of Minnesota, Twin Cities: Discover the vibrant campus life at the University of Minnesota. With its beautiful architecture and rich history, this modern university offers a dynamic environment where you can enjoy cultural events and explore innovative research.

Best time to go to Medicine Lake

The best time to visit Medicine Lake is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with no rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January15.1°F (-9.4°C)No RainMostly CloudyAverageSlightly Low
February17.1°F (-8.3°C)No RainMostly CloudyAverageSlightly Low
March32.7°F (0.4°C)Light RainMostly CloudyAverageAverage
April44.6°F (7.0°C)Light RainMostly CloudyAverageAverage
May58.5°F (14.7°C)Light RainMostly SunnyHighAverage
June68.9°F (20.5°C)Light RainMostly SunnyHighSlightly High
July73.4°F (23.0°C)Light RainMostly SunnyHighSlightly High
August71.4°F (21.9°C)Light RainMostly SunnyAverageSlightly High
September64.2°F (17.9°C)Light RainMostly SunnyAverageAverage
October49.3°F (9.6°C)Light RainMostly SunnyLowAverage
November35.4°F (1.9°C)No RainMostly SunnyLowAverage
December22.1°F (-5.5°C)No RainMostly CloudyLowSlightly Low

The nearest major airports for your trip to Medicine Lake

To visit Medicine Lake, you can fly into Minneapolis-St. Paul International Airport (MSP), located 20.9km away. Nearby hotel options include the luxurious InterContinental Minneapolis - St. Paul Airport, just 805m from MSP, and the Radisson Blu Mall of America, which is 4.8km from the airport. St. Paul Downtown Airport (STP) is another option, situated 29.0km from Medicine Lake, with hotels like the 4-star InterContinental Saint Paul Riverfront located 3.2km away. Lastly, St. Cloud Regional Airport (STC) is 78.9km from Medicine Lake, featuring the Best Western Plus Kelly Inn just 6.4km from STC. Each hotel offers easy access to their respective airports.

Frequently asked questions

What is Medicine Lake like?
Travelers are sure to enjoy a stay in Plymouth's Medicine Lake neighborhood.
If I need to cancel my hotel reservation in Medicine Lake, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Medicine Lake.
Where can I learn more about changing or cancelling my trip to Medicine Lake?
To access more information about picking new dates or cancelling your trip to Medicine Lake, head over to our customer service page.
What can I see and do in this Plymouth neighborhood?
A few places to visit in the area around Medicine Lake include French Park Beach, Sky Zone Indoor Trampoline Park, and Plymouth Playhouse. When you're sightseeing in Plymouth, Brookview Golf Course and Ridgedale Center are also worth a stop.

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