A tree-lined landscape with a river and fields.

Find hotels in East Prairie, MO from NT$2,072

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Sep 21 - Sep 22
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Our top choices for East Prairie hotels

1. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Scott
NT$2,991
NT$3,439 total
includes taxes & fees
Sep 27 - Sep 28
Drury Inn & Suites Sikeston, MO

2. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
michael
NT$3,214
NT$3,639 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express & Suites Sikeston Southwest by IHG

3. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
John
NT$3,236
NT$3,664 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn Sikeston

4. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Shelley
NT$2,775
NT$3,163 total
includes taxes & fees
Sep 27 - Sep 28
Best Western Plus Sikeston I-55

5. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
NT$3,214
NT$3,639 total
includes taxes & fees
Oct 1 - Oct 2
Fairfield Inn & Suites by Marriott Sikeston

6. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
William
NT$1,894
NT$2,101 total
includes taxes & fees
Sep 22 - Sep 23
Super 8 by Wyndham Charleston/Sikeston East MO

7. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Jay
NT$2,116
NT$2,348 total
includes taxes & fees
Sep 24 - Sep 25
The Riverstone Hotel Charleston-Sikeston

8. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Stacy
NT$3,469
NT$3,928 total
includes taxes & fees
Oct 11 - Oct 12
TownePlace Suites by Marriott Sikeston

9. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
Hazlo
NT$2,110
NT$2,405 total
includes taxes & fees
Sep 24 - Sep 25
Days Inn and Suites by Wyndham Sikeston

10. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
United States
Sharika West
NT$2,211
NT$2,521 total
includes taxes & fees
Sep 22 - Sep 23
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

11. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
United States
William
NT$1,950
NT$2,320 total
includes taxes & fees
Sep 22 - Sep 23
Country Yard Inn and Suite

12. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
Marston
United States
Rachel
NT$1,835
NT$2,096 total
includes taxes & fees
Sep 23 - Sep 24
Super 8 By Wyndham Marston

13. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
NT$2,450
NT$2,719 total
includes taxes & fees
Sep 22 - Sep 23
Eagle Inn Charleston

14. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
United States
Starlette
NT$2,813
NT$3,206 total
includes taxes & fees
Sep 27 - Sep 28
Comfort Inn & Suites Sikeston I-55

15. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
United States
Santiago
NT$2,254
NT$2,502 total
includes taxes & fees
Oct 2 - Oct 3
Quality Inn Cairo I-57

16. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
William
NT$1,818
NT$2,072 total
includes taxes & fees
Sep 28 - Sep 29
Super 8 by Wyndham Sikeston/Miner Area

17. Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
Marston
United States
Frank
NT$1,448
NT$1,741 total
includes taxes & fees
Sep 22 - Sep 23
Travel Inn Marston I-55 by Hotel O

18. Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
Union City
United States
Jade
NT$1,915
NT$2,274 total
includes taxes & fees
Oct 8 - Oct 9
Country Hearth Inn & Suites Union City

19. Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
Union City
United States
Terri
NT$3,755
NT$4,459 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express & Suites Union City by IHG

20. Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
Union City
United States
Ben
NT$2,492
NT$2,960 total
includes taxes & fees
Oct 11 - Oct 12
Sleep Inn at Discovery Park of America
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Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
A tree-lined landscape with a river and fields.

Top East Prairie Hotel Reviews

Hampton Inn Union City

Hampton Inn Union City

10/10 Excellent
"Clean room, friendly staff, good breakfast"
Caroline 1-night trip
Posted 16 hours ago
Hampton Inn Union City
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Excellent hotel"
Scott 1-night trip
Posted 17 hours ago
Drury Inn & Suites Sikeston, MO
Quality Inn Union City US 51

Quality Inn Union City US 51

10/10 Excellent
"Great stay for work. Really loved the hot tub."
Michael 1-night trip
Posted 19 hours ago
Quality Inn Union City US 51
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

10/10 Excellent
"Great clean room and property!"
Matthew 3-night trip
Posted 3 days ago
Sleep Inn at Discovery Park of America
Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"Clean room not so friendly staff"
Rica 1-night trip
Posted 3 days ago
Hampton Inn Sikeston
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"The man at the front desk was very helpful and polite"
William 1-night trip
Posted 4 days ago
Super 8 by Wyndham Sikeston/Miner Area
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

8/10 Good
"Love the staff and the parking and the quiet"
Stefani 2-night trip
Posted 4 days ago
Holiday Inn Express & Suites Union City by IHG
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

8/10 Good
"Overall it was excellant, other then the toilet running constantly... Pool could have been cleaner, considering the heat-wave they were having............."
Mark E 13-night trip
Posted 8 days ago
The Riverstone Hotel Charleston-Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"Clean room. The front desk was very kind and helpful."
Mercedes 3-night trip
Posted 10 days ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

More cheap stays in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO
NT$1,818
NT$2,072 total
Sep 28 - Sep 29
includes taxes & fees
7/10 Good! (676 reviews)
Super 8 by Wyndham Sikeston/Miner Area
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
NT$2,110
NT$2,405 total
Sep 24 - Sep 25
includes taxes & fees
7.2/10 Good! (1,006 reviews)
Days Inn and Suites by Wyndham Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO
NT$2,211
NT$2,521 total
Sep 22 - Sep 23
includes taxes & fees
8.4/10 Very Good! (821 reviews)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

1111 BLue Heron Lane Union City TN
NT$2,492
NT$2,960 total
Oct 11 - Oct 12
includes taxes & fees
9.2/10 Wonderful! (434 reviews)
Sleep Inn at Discovery Park of America
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO
NT$2,775
NT$3,163 total
Sep 27 - Sep 28
includes taxes & fees
Best Western Plus Sikeston I-55
Hampton Inn Sikeston

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO
NT$3,236
NT$3,664 total
Oct 4 - Oct 5
includes taxes & fees
9/10 Wonderful! (623 reviews)
Hampton Inn Sikeston

Hotels in East Prairie with star-rating

Find out more about East Prairie

Top reasons to visit East Prairie

  • Outdoor Adventures: East Prairie offers scenic trails and recreational areas perfect for hiking, skiing, and family picnics.
  • Cultural Experiences: Immerse yourself in local history at museums and enjoy events at various conference venues.
  • Charming Accommodations: A range of comfortable lodging options are available, catering to families, pets, and business travelers.
  • Nearby Attractions: Explore nearby national parks and shopping opportunities just a short drive away.
  • Welcoming Atmosphere: Friendly locals enhance your travel experience, making for lasting memories.

Find great hotels near East Prairie

Discover a variety of comfortable accommodations in East Prairie, Missouri, perfect for every type of traveler. Whether you're seeking pet-friendly options for a family vacation or convenient lodging for business trips, you'll find a range of hotels and motels to suit your needs. Explore the best hotels in East Prairie, complete with helpful amenities and positive reviews to ensure a memorable stay in this charming town.

  • Days Inn and Suites by Wyndham Sikeston: This hotel is an ideal choice for travelers seeking a blend of comfort and convenience, especially those on business trips or traveling with pets. Located 17.7km from East Prairie, this property welcomes furry friends and features a pet-friendly policy, allowing dogs and cats. Guests appreciate the essential amenities such as complimentary breakfast and free Wi-Fi, ensuring a hassle-free stay. The warm and inviting atmosphere makes it a great home base for exploring the nearby attractions while enjoying the comforts of home.
  • Drury Inn & Suites Sikeston, MO: Known for its family-friendly environment, this 3-star hotel is also LGBTQIA welcoming, making it a standout option for diverse travelers. Situated 17.7km from East Prairie, Drury Inn offers exceptional amenities for children, including free cribs, and a range of pet-friendly options. Guests can indulge in complimentary hot breakfast and evening snacks, enhancing the overall experience. The welcoming atmosphere, combined with a focus on community and comfort, makes this hotel a top choice for families and friends looking to enjoy a memorable stay.
  • Pear Tree Inn Sikeston: This charming hotel, located 17.7km from East Prairie, caters to business travelers and families alike, with a welcoming stance toward LGBTQIA guests. Pear Tree Inn offers a cozy ambiance, complete with family-friendly amenities such as free cribs for younger guests. The property’s commitment to excellent service and comfort makes it an appealing choice for those traveling for work or leisure. With its convenient location and thoughtful features, guests can unwind after a day of exploring or meetings, making it a perfect retreat.

Where to stay near East Prairie

Discover the charm of East Prairie, Missouri, where outdoor enthusiasts and relaxation seekers unite. Explore the nearby open spaces, perfect for family-friendly excursions or a romantic picnic. Just a short drive from downtown Sikeston, you'll find delightful shopping opportunities and a warm, welcoming atmosphere. Don't miss the chance to unwind in this scenic region, where friendly locals enhance your travel experience and create lasting memories.

  • Sikeston: Located 20.9km from East Prairie, Sikeston offers a blend of outdoor adventure and family-friendly activities. Visitors can enjoy the local recreational areas, perfect for picnics and outdoor games. The city’s shopping centers provide great opportunities for retail therapy, while the nearby lake and event conference venues serve as popular attractions. Sikeston is ideal for those seeking a romantic getaway or a fun family vacation, particularly during the summer months when the weather is perfect for exploration.
  • Anniston: Just 8.0km away from East Prairie, Anniston is a charming city that caters to families and outdoor enthusiasts alike. With its urban parks and stadium, there's plenty of space for relaxation and recreational activities. The shopping centers and malls make it a convenient spot for those looking to indulge in some retail therapy. Anniston’s appeal lies in its blend of city life and green spaces, making it a delightful stop for travelers looking for a balanced experience.
  • Charleston: Situated 16.1km from East Prairie, Charleston is a city known for its stunning scenery and adventurous spirit. The nearby national state park and historic sites offer a fascinating glimpse into the area’s past while providing ample opportunities for hiking and outdoor activities. With recreational areas and shopping centers, Charleston is perfect for visitors looking to explore both nature and local culture. Its vibrant atmosphere and seasonal events make it an exciting destination throughout the year.

Things to do near East Prairie

East Prairie, Missouri, is perfect for outdoor and romantic getaways, offering a blend of scenic beauty and recreational activities. Visitors can explore the area's trails, enjoy skiing, and relax in the local recreational areas. For those interested in prairie tourism, East Prairie also features several major attractions that showcase the region's natural charm and rich culture, making it an ideal destination for nature lovers and adventure seekers alike.

Shopping

In East Prairie, visit local shops for unique souvenirs and gifts. If you're up for a drive, check out County Market Place, located 49.9km away, where you can enjoy a vibrant atmosphere with family-friendly options and diverse shopping experiences.

Recreation

East Prairie offers peaceful retreats like the Wellness Center, where you can indulge in yoga classes and soothing massages. Explore the nearby Mississippi River for fishing, kayaking, and hiking trails, providing a perfect blend of relaxation and outdoor adventure in a picturesque setting.

Adventure

In East Prairie, explore the stunning landscapes at the nearby Mississippi River, perfect for kayaking and fishing. Experience the thrill of off-roading at local ATV trails, or hike through scenic routes in the nearby wetlands, where wildlife viewing is abundant and nature thrives.

Nightlife

In East Prairie, the nightlife scene is vibrant yet relaxed. A short drive to Union City Masquerade Theatre offers an enchanting mix of romance and culture, perfect for a memorable evening filled with live performances and entertainment that will leave you captivated.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for East Prairie

For a budget-friendly trip to East Prairie, visit during the cheapest months of December to February, and consider staying on Sundays for lower rates. Utilize Expedia to compare hotel prices, focusing on deals that combine accommodations with flights and activities. Look for hotels with business amenities if needed, and sort options from lowest to highest price to find the best deals. Free activities in the area can also help stretch your budget further, making your visit enjoyable without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in East Prairie are December to February, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in East Prairie is Sunday. The most expensive day to stay in East Prairie is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to narrow down your choices based on your budget, desired location, and preferred hotel type. To discover the most affordable options and special offers, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your East Prairie hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions near East Prairie

East Prairie, Missouri, offers a delightful blend of outdoor adventures, scenic views, and romantic getaways. Visitors can explore nearby national parks, immerse themselves in local history at museums, and attend events at conference venues. This charming town is perfect for those seeking cultural experiences while enjoying nature. Be sure to check out nearby attractions to enhance your visit and make the most of your time in this picturesque area.

  • Central Park: Located 20.9km from East Prairie, Central Park offers a vibrant urban atmosphere perfect for families. Enjoy leisurely strolls, picnics, and various outdoor activities amidst beautiful landscapes and city vibes.
  • Sikeston Depot Museum: This art museum, also 20.9km away, boasts a rich cultural experience. Explore exhibits that showcase local history, art, and the heritage of the area, providing a deeper understanding of the community's roots.
  • Columbus-Belmont State Park: Situated 24.1km from East Prairie, this national state park is a haven for outdoor enthusiasts. With stunning scenery and ample opportunities for adventure, visitors can hike, fish, and enjoy a variety of recreational activities surrounded by nature.

Best time to go to East Prairie

The best time to visit East Prairie is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January36.3°F (2.4°C)Light RainMostly SunnyModerately HighSlightly Low
February39.4°F (4.1°C)Light RainMostly SunnyAverageSlightly Low
March49.5°F (9.7°C)Light RainMostly SunnyAverageAverage
April58.5°F (14.7°C)Light RainMostly SunnyAverageSlightly High
May68.2°F (20.1°C)Light RainMostly SunnyAverageAverage
June77.0°F (25.0°C)Light RainMostly SunnyModerately HighSlightly High
July79.5°F (26.4°C)Light RainMostly SunnyModerately HighAverage
August77.5°F (25.3°C)Light RainMostly SunnyAverageSlightly High
September72.1°F (22.3°C)Light RainMostly SunnyAverageAverage
October60.8°F (16.0°C)Light RainMostly SunnyModerately LowAverage
November48.6°F (9.2°C)Light RainMostly SunnyModerately LowAverage
December41.2°F (5.1°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to East Prairie

For your trip to East Prairie, Missouri, you have a few airport options. Cape Girardeau Municipal Airport (CGI) is 51.5km away, with nearby hotels like the 3-star Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott, both 9.7km from the airport. Cairo Regional Airport (CIR) is closer at 33.8km, offering options such as the Quality Inn just 3.2km away. Lastly, Barkley Regional Airport (PAH) in Paducah, Kentucky, is 62.8km from East Prairie, with notable stays like The Respite Bed and Breakfast, situated 14.5km from the airport. Transportation services are available to connect you to these accommodations.

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
Where can I learn more about changing or cancelling my trip to East Prairie?
To access more information about rescheduling or cancelling your trip to East Prairie, click here.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 36 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Columbus-Belmont State Park and Fort Defiance State Park in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.

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