East Prairie Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 21 - Dec 22
Tomorrow
Dec 22 - Dec 23
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top East Prairie Hotel Reviews

Best Western Plus Sikeston

Best Western Plus Sikeston

10/10 Excellent
"Great stay, everything was clean and comfortable. "
Charles 1-night trip
Posted 22 hours ago
Best Western Plus Sikeston

Find out more about East Prairie

Search for holiday rentals in East Prairie on Expedia! You can easily find your home rentals, villas, holiday apartments in East Prairie using one of the methods below:

  • View our selection of featured holiday rentals in East Prairie
  • Use the map to find apartments and other holiday homes in the East Prairie neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in East Prairie while they last

Look no further and take a look at our great range of rental properties in East Prairie!

Frequently asked questions

Can I find a vacation rental in East Prairie?

Yes, you can find vacation rentals near the most popular sights in East Prairie, or you can select a more secluded option if you're looking for a relaxing stay.

What can I see and do in East Prairie?

Mississippi River and Big Oak Tree State Park are a couple of lovely local spots to get outside and enjoy nature. In the larger area, you’ll find Central Park and River Ridge Winery.

What are vacation rentals like in East Prairie?

Vacation rentals are privately owned accommodations you can reserve for a few days or a quick weekend in East Prairie. Vacation rentals feature extras like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for family trips.