Photo by Ryan Coleman

Find hotels in Sikeston, MO from NT$1,795

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Compare 256 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (371)
"Great location and clean room. Plenty of food and shopping nearby."
The price is NT$3,162
NT$3,581 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn Sikeston

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (733)
"Great place to stay convenient walking to multiple restaurants"
The price is NT$3,264
NT$3,682 total
includes taxes & fees
Aug 17 - Aug 18
Hampton Inn Cape Girardeau I 55 East

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Very clean, friendly staff, and reasonable rates. "
The price is NT$2,678
NT$3,079 total
includes taxes & fees
Sep 1 - Sep 2
Drury Inn & Suites Sikeston, MO

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (593)
"This was a great hotel at a great price!"
The price is NT$2,378
NT$2,574 total
includes taxes & fees
Sep 1 - Sep 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (373)
"A very cool destination!"
The price is NT$3,134
NT$3,536 total
includes taxes & fees
Aug 17 - Aug 18
The Riverview

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great place to stay. "
The price is NT$3,066
NT$3,459 total
includes taxes & fees
Aug 17 - Aug 18
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (971)
"Easy access and parking"
The price is NT$2,678
NT$3,021 total
includes taxes & fees
Aug 17 - Aug 18
Drury Inn & Suites Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (435)
"Very clean and upscale hotel."
The price is NT$3,721
NT$4,216 total
includes taxes & fees
Sep 7 - Sep 8
Courtyard by Marriott Cape Girardeau Downtown

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (421)
"Close in eating and shopping "
The price is NT$3,006
NT$3,404 total
includes taxes & fees
Sep 5 - Sep 6
Holiday Inn Express & Suites Sikeston Southwest by IHG

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1005)
"Complimentary happy hour with appetizers was amazing! Great breakfast also."
The price is NT$3,036
NT$3,425 total
includes taxes & fees
Aug 14 - Aug 15
Drury Plaza Hotel Cape Girardeau Conference Center

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very Good, (891)
" Love the stay and staff was great "
The price is NT$1,923
NT$2,201 total
includes taxes & fees
Sep 1 - Sep 2
Super 8 by Wyndham Perryville

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (117)
"Hotel was very clean and the lady that checked us in was very friendly. "
The price is NT$2,768
NT$3,123 total
includes taxes & fees
Aug 17 - Aug 18
Fairfield Inn & Suites by Marriott Cape Girardeau

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1002)
"We enjoyed our stay and the breakfast was good!"
The price is NT$2,623
NT$2,989 total
includes taxes & fees
Aug 17 - Aug 18
Best Western Plus Sikeston

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great place to stay with kids "
The price is NT$2,381
NT$2,737 total
includes taxes & fees
Aug 13 - Aug 14
Pear Tree Inn Sikeston

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (459)
"Staff was very friendly, and the room was clean, and cozy, with the bed being very comfortable!"
The price is NT$3,095
NT$3,435 total
includes taxes & fees
Sep 7 - Sep 8
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1003)
"We had a last minute reservation here. The staff was very pleasant, helpful and wonderful overall!!"
The price is NT$2,678
NT$2,832 total
includes taxes & fees
Aug 12 - Aug 13
Drury Inn & Suites Jackson MO

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (494)
"Super nice staff. Our room smelled so nice and clean. Breakfast was very good too! "
The price is NT$3,274
NT$3,748 total
includes taxes & fees
Aug 10 - Aug 11
Holiday Inn Express & Suites Perryville by IHG

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
9.4 out of 10, Exceptional, (17)
"Nice hotel "
The price is NT$3,146
NT$3,562 total
includes taxes & fees
Aug 17 - Aug 18
Fairfield Inn & Suites by Marriott Sikeston

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1000)
"We enjoyed the quick check in and how quiet the property was. "
The price is NT$2,083
NT$2,350 total
includes taxes & fees
Aug 10 - Aug 11
Pear Tree Inn Cape Girardeau West

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (51)
"Great overall stay"
The price is NT$2,783
NT$3,167 total
includes taxes & fees
Aug 17 - Aug 18
Tru By Hilton Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Sikeston attractions

Sikeston Depot Museum

Sikeston Depot Museum

You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

Central Park

Central Park

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best pet-friendly accommodation in Sikeston?

Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Best Western Plus Sikeston and Pear Tree Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What's the best hotel for a golf vacation in Sikeston?

Travel Inn & Suites is a hotel featuring free breakfast and free WiFi, and it's a top choice for playing a round of golf. You can tee off at Boot Heel Golf Club during your trip. See more golf hotels in Sikeston.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.

What is the best spa hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top spa hotel featuring a pool and a fitness center. See all spa hotels in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

A couple of favorite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.