Photo by Ryan Coleman

Find hotels in Sikeston, MO from NT$2,261

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Our top choices for Sikeston hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is NT$2,838
NT$3,201 total
includes taxes & fees
Dec 23 - Dec 24
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"Clean room, great location and friendly staff"
United States
Mark
The price is NT$2,838
NT$3,263 total
includes taxes & fees
Dec 26 - Dec 27
Drury Inn & Suites Sikeston, MO

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1005)
"Easy parking , quiet and comfortable bed , we’ll stop again on our way back "
United States
joseph
The price is NT$2,384
NT$2,717 total
includes taxes & fees
Dec 21 - Dec 22
Best Western Plus Sikeston

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1000)
"Great stay"
United States
Heather
The price is NT$2,207
NT$2,490 total
includes taxes & fees
Dec 23 - Dec 24
Pear Tree Inn Cape Girardeau West

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is NT$2,996
NT$3,380 total
includes taxes & fees
Dec 25 - Dec 26
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (719)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is NT$1,750
NT$1,994 total
includes taxes & fees
Dec 23 - Dec 24
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (669)
"Great place "
United States
GUY
The price is NT$2,654
NT$2,872 total
includes taxes & fees
Dec 20 - Dec 21
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is NT$3,658
NT$4,145 total
includes taxes & fees
Dec 28 - Dec 29
Courtyard by Marriott Cape Girardeau Downtown

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (474)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is NT$3,037
NT$3,426 total
includes taxes & fees
Dec 22 - Dec 23
The Riverview

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Very friendly staff and great breakfast"
United States
Ray
The price is NT$2,838
NT$3,201 total
includes taxes & fees
Dec 25 - Dec 26
Drury Inn & Suites Cape Girardeau

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"Everything was clean, staff was friendly "
United States
Matthew
The price is NT$2,365
NT$2,719 total
includes taxes & fees
Dec 23 - Dec 24
Pear Tree Inn Sikeston

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is NT$2,617
NT$2,767 total
includes taxes & fees
Dec 25 - Dec 26
Drury Inn & Suites Jackson MO

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
The price is NT$2,775
NT$3,131 total
includes taxes & fees
Dec 28 - Dec 29
Fairfield Inn & Suites by Marriott Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is NT$2,207
NT$2,490 total
includes taxes & fees
Dec 23 - Dec 24
Pear Tree Inn Cape Girardeau Near the Medical Center

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
The price is NT$2,933
NT$3,321 total
includes taxes & fees
Jan 11 - 2026/1/12
Holiday Inn Express & Suites Sikeston Southwest by IHG

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (385)
"Very nice"
United States
Dennis
The price is NT$2,342
NT$2,629 total
includes taxes & fees
Dec 21 - Dec 22
Travelodge by Wyndham Dexter

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (445)
"Friendly staff clean rooms "
United States
Christopher
The price is NT$3,078
NT$3,485 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn Sikeston

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (882)
"Room was clean and spacious."
United States
George
The price is NT$2,428
NT$2,913 total
includes taxes & fees
Jan 19 - 2026/1/20
Candlewood Suites Cape Girardeau by IHG

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (684)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is NT$1,816
NT$2,049 total
includes taxes & fees
Dec 25 - Dec 26
Quality Inn Cape Girardeau North

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1001)
"A great stay in every aspect. "
United States
Gertrude
The price is NT$1,984
NT$2,261 total
includes taxes & fees
Dec 23 - Dec 24
Days Inn and Suites by Wyndham Sikeston
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Stay near popular Sikeston attractions

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

More cheap stays in Sikeston

Hotels in Sikeston with star-rating

Find out more about Sikeston

Top reasons to visit Sikeston

  • Outdoor Adventures: Sikeston offers numerous recreational areas, perfect for hiking, biking, and outdoor activities.
  • Family-Friendly Attractions: Enjoy engaging experiences at local parks, museums, and the famous Sikeston Depot.
  • Live Entertainment: The city hosts various events and shows, providing fun for all ages.
  • Charming Small-Town Atmosphere: Experience the warmth of local hospitality and a friendly community vibe.
  • Comfortable Accommodations: Choose from a range of hotels and motels that cater to all travelers.

Find great hotels in Sikeston

Discover a range of comfortable accommodations in Sikeston, Missouri, designed to cater to every type of traveler. From pet-friendly hotels to welcoming options for business travelers and the LGBTQIA community, you'll find the perfect place to stay. Explore popular choices like the Hampton Inn and various motels and suites that offer excellent amenities for a pleasant vacation experience.

  • Days Inn and Suites by Wyndham Sikeston: Emphasizing convenience and comfort, Days Inn and Suites by Wyndham Sikeston offers a welcoming atmosphere perfect for both business travelers and those traveling with pets. This hotel provides essential amenities including free Wi-Fi, a business center, and pet-friendly accommodations with specific policies for dogs and cats. Guests can enjoy a complimentary breakfast to kick-start their day. With its practical features and friendly service, it’s an ideal choice for those seeking a stress-free stay in Sikeston.
  • Drury Inn & Suites Sikeston, MO: Drury Inn & Suites Sikeston, MO, a 3-star hotel, stands out for its commitment to inclusivity and exceptional service. Perfect for business travelers, this hotel offers a range of amenities including a fitness center, free breakfast, and business facilities. Known for its LGBTQIA-friendly environment, this property ensures a welcoming experience for all guests. With a focus on comfort and convenience, Drury Inn aims to provide a relaxing retreat after a long day of work or exploration.
  • Pear Tree Inn Sikeston: Pear Tree Inn Sikeston combines family-friendly amenities with a welcoming atmosphere for LGBTQIA travelers. This hotel offers complimentary breakfasts and features such as a children’s area with free cribs, making it an ideal choice for families. Guests will appreciate the hotel’s convenient location and the caring staff, dedicated to ensuring a pleasant stay. With a mix of comfort and family-oriented services, Pear Tree Inn is a great option for those seeking both leisure and quality time with loved ones.

Where to stay in and around Sikeston

Sikeston, Missouri, is a charming small town perfect for outdoor adventures and family getaways. Visitors enjoy a friendly atmosphere, making it an ideal spot for romantic escapes or relaxing vacations. With its convenient location, Sikeston serves as a great base for exploring nearby attractions. Experience the warmth of local hospitality while discovering family-friendly activities and excursions in the Sikeston area. This hidden gem offers a delightful blend of small-town charm and vibrant experiences.

  • Miner: Nestled in the vicinity of Sikeston, Miner is a charming village that offers a unique blend of city-themed and outdoor experiences. Visitors can expect to enjoy a variety of recreational activities and educational venues throughout the year. The peak travel seasons in January and from June to July attract tourists looking for culture and community vibes. Highlights include access to a modern college university and a bustling tourist precinct, making it a great destination for those interested in local culture and outdoor adventures.
  • Bertrand: Located just 12.9km from Sikeston, Bertrand is a picturesque city surrounded by natural beauty. Known for its outdoor and adventure experiences, this city is a perfect getaway for nature lovers. The peak travel months are April, August, and December to January, offering scenic landscapes that entice visitors year-round. Bertrand is in close proximity to a national park, lush forests, and tranquil lakes, providing ample opportunities for hiking, fishing, and enjoying the great outdoors.
  • Matthews: Also situated 12.9km away from Sikeston, Matthews is a delightful city that promises romantic outdoor experiences amid stunning scenery. The summer months from June to August see the highest number of visitors, drawn by the lush campgrounds and recreational areas. Nearby attractions include a lovely lake, a national state park, and a history museum, making it a well-rounded destination for those seeking both adventure and a glimpse into the local heritage.

Things to do near Sikeston

Sikeston, Missouri, is perfect for outdoor adventures and family-friendly activities. Visitors can enjoy its recreational areas, explore shopping centers, and engage in educational experiences. The city also offers live entertainment, making it an ideal destination for both romantic getaways and family vacations. Whether you're looking to relax or have fun, Sikeston has a variety of options to suit all interests.

Shopping

Sikeston offers great shopping at the Sikeston Factory Outlet Stores, featuring various brand-name shops. If you're up for a drive, head to the nearby Cape Girardeau Mall with more extensive options, including department stores and a variety of dining choices for a full shopping day.

Recreation

eDen Spa & Salon offers a rejuvenating body treatment experience, located 46.7km from Sikeston. This tranquil venue provides a perfect atmosphere for relaxation, featuring soothing ambiance and a range of wellness services designed to help you unwind and revitalize your spirit.

Adventure

Experience the thrill of outdoor activities at Sikeston's recreation areas. Explore hiking trails in nearby parks, enjoy fishing at local lakes, or take part in kayaking adventures. For an adrenaline rush, consider visiting local zipline parks or go for a scenic bike ride through the picturesque countryside.

Nightlife

Explore the vibrant nightlife at the Sikeston Elks Lodge for great socializing and events. For a lively atmosphere, visit the American Legion where you can enjoy dancing and local music. Don’t miss out on the cozy vibe at the K of C Hall, perfect for drinks and mingling.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Sikeston

To save money on your trip to Sikeston, visit between November and January when hotel prices are lower, and consider booking your stay for a Tuesday, the cheapest day. Use Expedia to find budget-friendly accommodations by sorting results for the lowest prices and filtering for eco-friendly options. Additionally, you can save further by bundling your hotel, flights, and activities. Look for exclusive deals, compare room rates, and take advantage of offers like free nights to maximize savings during your visit.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Sikeston are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Sikeston is Tuesday. The most expensive day to stay in Sikeston is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool lets you choose your budget, desired location, and additional preferences. You can easily sort the results to display the lowest prices first, ensuring you find the most affordable hotel options right away. Plus, you can narrow down your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and eco-friendly hotels available for booking.
  • Consider bundling your trip: You can save money by combining your Sikeston hotel reservations with your flights and activities through an Expedia package.

Find the best attractions in and around Sikeston

Sikeston, Missouri, is perfect for outdoor, family, and romantic getaways, offering a variety of attractions such as the Sikeston Depot, local parks, and art museums. Visitors can immerse themselves in culture while enjoying the beauty of urban parks and event venues, ensuring a memorable experience for all types of travelers. Whether you seek adventure or relaxation, Sikeston has something for everyone.

  • Sikeston Depot Museum: Explore the rich cultural history of Sikeston at the Sikeston Depot Museum. This charming museum showcases local art and historical artifacts, offering visitors a glimpse into the area's vibrant past and artistic endeavors.
  • Central Park: Enjoy a refreshing outdoor experience at Central Park, an urban oasis perfect for families. With playgrounds, picnic areas, and walking trails, it’s an ideal spot for relaxation and recreational activities in a city setting.
  • Front Street Studio & Art Gallery: Located 14.5km away, Front Street Studio & Art Gallery features an impressive collection of local artworks. Immerse yourself in the local art scene and discover unique pieces that reflect the culture and creativity of the region.

Best time to go to Sikeston

The best time to visit Sikeston can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Sikeston falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Sikeston falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January36.0°F (2.2°C)Light RainMostly SunnySlightly LowSlightly Low
February39.2°F (4.0°C)Light RainMostly SunnySlightly LowAverage
March49.5°F (9.7°C)Light RainMostly SunnyAverageAverage
April58.5°F (14.7°C)Light RainMostly SunnyAverageSlightly High
May68.2°F (20.1°C)Light RainMostly SunnyAverageSlightly High
June77.2°F (25.1°C)Light RainMostly SunnySlightly HighSlightly High
July79.5°F (26.4°C)Light RainMostly SunnySlightly HighAverage
August77.5°F (25.3°C)Light RainMostly SunnySlightly HighAverage
September72.1°F (22.3°C)Light RainMostly SunnyAverageAverage
October60.8°F (16.0°C)Light RainMostly SunnyAverageAverage
November48.6°F (9.2°C)Light RainMostly SunnyAverageSlightly Low
December41.2°F (5.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Sikeston

Traveling to Sikeston, Missouri, can be done via several nearby airports. Cape Girardeau Municipal Airport (CGI) is 38.6km away, with excellent hotel options like Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown, both 9.7km from the airport. Cairo Regional Airport (CIR) is also 38.6km from Sikeston, offering nearby accommodations such as Quality Inn Cairo I-57, just 3.2km away. For those flying into Barkley Regional Airport (PAH) in Paducah, KY, located 75.6km away, consider The Respite Bed and Breakfast, a charming 4.5-star option just 14.5km from the airport.

Frequently asked questions

Where is the best place to stay in Sikeston?
Pear Tree Inn Sikeston is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Fairfield Inn & Suites by Marriott Sikeston and Drury Inn & Suites Sikeston, MO. See all available top hotels, or vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
Where can I learn more about changing or cancelling my trip to Sikeston?
For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.
What's the best hotel for a family vacation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.
What is the top LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best pet-friendly accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Days Inn and Suites by Wyndham Sikeston and Hampton Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.
Where is the best hotel to stay close to Central Park?
Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.
What about the best place to stay close to Sikeston Depot Museum?
One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.
What are some accommodations with pools in Sikeston?
Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.
What's the best place to stay near Barkley Regional Airport (PAH)?
Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.
What is staying in Sikeston like?
Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.
What are the top places to visit in Sikeston?
A couple of favorite places to visit are Central Park and Sikeston Depot Museum. You'll also find River Ridge Winery and Front Street Studio & Art Gallery in the area. Check out what more to see and do in Expedia's Sikeston guide.
What's the seasonal weather like in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.

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