Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.
This versatile 16,000-square-foot venue in Miner, Missouri hosts conferences, weddings, and community gatherings. Modern meeting rooms and a commercial kitchen make it ideal for various events.
Central Park offers a peaceful retreat with playgrounds and open spaces for Sikeston families. Bring a blanket for a relaxing picnic or watch children enjoy the recreational facilities.
Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.
I loved this property! They had everything I look for. Indoor pool was spotless &
stocked well with towels. We enjoyed the layout of the lobby, bar & eating area with multiple big screens & gift shop with frozen food & treats for those that get a little hungry. Our room & bathroom were spacious & well designed. We travel with our pup so we were very happy with the area on 2 sides with grassy areas & dog baggy collection to keep the yard clean for all dog walkers. It was the most area I’ve seen...
I loved this property! They had everything I look for. Indoor pool was spotless &
stocked well with towels. We enjoyed the layout of the lobby, bar & eating area with multiple big screens & gift shop with frozen food & treats for those that get a little hungry. Our room & bathroom were spacious & well designed. We travel with our pup so we were very happy with the area on 2 sides with grassy areas & dog baggy collection to keep the yard clean for all dog walkers. It was the most area I’ve seen...
ANGELA
Reviewed October 24, 2026Reviewed October 24, 2026
The staff was so courteous. Check in and check out. The lady that ran the food area was amazing and kind to everyone no matter how busy she was. She was running around and doing so much and it was so refreshing that she was so kind despite working hard and us interrupting her to ask a question. Even the cleaning staff went out of their way to be friendly to us.
The staff was so courteous. Check in and check out. The lady that ran the food area was amazing and kind to everyone no matter how busy she was. She was running around and doing so much and it was so refreshing that she was so kind despite working hard and us interrupting her to ask a question. Even the cleaning staff went out of their way to be friendly to us.
Outdoor Adventures: Sikeston offers a range of outdoor activities, perfect for family getaways and nature lovers.
Local Cuisine: Don't miss the famous Sikeston BBQ, a culinary highlight that showcases the local flavor.
Cultural Exploration: Visit art museums and historic houses for a taste of Sikeston's rich cultural heritage.
Shopping Experience: Enjoy shopping at the local center featuring various outlet stores for great deals.
Welcoming Atmosphere: Experience the charm of small-town Sikeston with friendly locals and a relaxed vibe.
Find great hotels in Sikeston
Experience a delightful stay in Sikeston, Missouri, where a variety of lodging options await you. From pet-friendly motels to welcoming hotels catering to business travelers and the LGBTQIA community, there’s something for everyone. Explore popular choices like the Comfort Inn and Pear Tree Inn, and find the perfect suite for your getaway. With numerous reviews available, you can easily discover the best accommodations for your vacation needs.
Days Inn and Suites by Wyndham Sikeston: A budget-friendly option, Days Inn and Suites by Wyndham Sikeston caters to both business travelers and those seeking a pet-friendly getaway. Located conveniently in Sikeston, this hotel allows pets, accommodating dogs and cats with specific weight limits. With an emphasis on comfort and value, the property offers essential amenities for a pleasant stay, making it ideal for guests traveling with their furry companions.
Drury Inn & Suites Sikeston, MO: Rated highly with a guest score of 9.6, Drury Inn & Suites Sikeston, MO offers a delightful blend of family-friendly and business-focused amenities. This 3-star hotel is well-equipped for children, including complimentary cribs. Also welcoming pets, the hotel accommodates dogs and cats, ensuring a hassle-free stay for those traveling with pets. Guests appreciate the thoughtful amenities and the warm, inviting atmosphere that makes this hotel a top choice for a comfortable stay.
Best Western Plus Sikeston I-55: A budget-friendly option with a solid guest rating of 8.4, Best Western Plus Sikeston I-55 is another excellent choice for pet owners. Situated conveniently in Sikeston, this hotel allows pets and features specific policies that ensure a welcoming environment for both guests and their furry friends. With comfortable accommodations and essential amenities, this hotel provides a cozy base for exploring the surrounding area.
Where to stay in and around Sikeston
Discover the charm of Sikeston, Missouri, where outdoor adventures and family-friendly fun await. Stroll through the welcoming neighborhoods and indulge in local cuisine, including the famous Sikeston BBQ. Explore nearby attractions like the picturesque Southeast Missouri region, perfect for road trips and relaxing getaways. With its small-town vibe and friendly people, Sikeston offers a memorable experience for vacationers seeking both adventure and relaxation.
Miner: Nestled in the vicinity of Sikeston, Miner is a charming village that offers a blend of culture and outdoor experiences. Its visitor numbers are fairly consistent throughout the year, with peaks in January and during the summer months of June and July. Travelers flock to Miner for its city-themed attractions, educational facilities, and local shopping centers. Notable highlights include a modern college university and a vibrant tourist precinct that showcases unique street life. With a mix of arena entertainment and outdoor activities, Miner provides a delightful escape for those looking to explore local culture and community.
Bertrand: Located approximately 13km from Sikeston, Bertrand is a city that thrives on outdoor adventures and stunning scenery. The travel experience here is quite stable year-round, with peaks in April, August, and the holiday season. Visitors come to Bertrand to enjoy its beautiful golf courses nestled within lush landscapes, as well as nearby forests and lakes that invite exploration. The proximity to the national state park adds to the allure, offering opportunities for hiking, fishing, and picnicking. Bertrand’s serene environment makes it a perfect getaway for nature lovers and adventure enthusiasts alike.
Matthews: Also situated about 13km from Sikeston, Matthews is a scenic city perfect for outdoor enthusiasts and those seeking a romantic getaway. Visitor traffic peaks in the summer months, particularly from June to August, making it an ideal time to enjoy its recreational areas and campgrounds. The local attractions include picturesque lakes and a national state park, providing ample opportunities for outdoor activities like hiking and water sports. Additionally, the local museum offers a glimpse into the area's history, making Matthews a well-rounded destination for both adventure and culture seekers.
Things to do in Sikeston
Shopping
Sikeston offers unique shopping experiences at the Sikeston Factory Outlet Stores, where you can find discounts on various brands. If you're up for a drive, visit the nearby Cape Girardeau Mall for a wider selection of shops, including department stores and specialty boutiques.
Recreation
In Sikeston, relax at the Sikeston Wellness Center, offering yoga classes and holistic therapies to rejuvenate your mind and body. Enjoy outdoor activities at the nearby Sikeston City Park, where you can stroll scenic trails, picnic, or engage in recreational sports for a refreshing experience.
Adventure
Explore the Sikeston Depot Museum for a glimpse into local history and culture. For outdoor adventure, try fishing at Lake Wappapello, where scenic views and serene waters create a peaceful escape. Consider hiking in nearby parks to enjoy nature and wildlife in the area.
Nightlife
Experience the vibrant atmosphere at the Sikeston Jaycee Bootheel Rodeo, where you can enjoy live music and local cuisine. For a laid-back evening, visit the Barbecue Joint for great food and drinks. Don’t miss the chance to mingle with friendly locals at the Sikeston VFW Post.
*Distances are measured in a straight line; actual driving distances may vary depending on the route.
Booking tips and Expedia advantages for Sikeston
To save money on your trip to Sikeston, visit between November and January when hotel prices are lower, and consider booking your stay for a Tuesday, the cheapest day. Use Expedia to find budget-friendly accommodations by sorting results for the lowest prices and filtering for eco-friendly options. Additionally, you can save further by bundling your hotel, flights, and activities. Look for exclusive deals, compare room rates, and take advantage of offers like free nights to maximize savings during your visit.
The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Sikeston are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher.
The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Sikeston is Tuesday. The most expensive day to stay in Sikeston is Saturday.
Find cheap hotels on Expedia: Expedia's search tool lets you choose your budget, desired location, and additional preferences. You can easily sort the results to display the lowest prices first, ensuring you find the most affordable hotel options right away. Plus, you can narrow down your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and eco-friendly hotels available for booking.
Consider bundling your trip: You can save money by combining your Sikeston hotel reservations with your flights and activities through an Expedia package.
Find the best attractions in and around Sikeston
Sikeston, Missouri, is perfect for outdoor, family, and romantic getaways, offering attractions like art museums, urban parks, and historic houses. Visitors can immerse themselves in local culture and city life while exploring the Sikeston Power Plant and the Sikeston Depot. Whether you're seeking family experiences or a taste of history, Sikeston has something for everyone to enjoy.
Central Park: Enjoy a serene escape in Central Park, an urban oasis in the heart of Sikeston. This park offers family-friendly outdoor spaces perfect for picnics, leisurely strolls, and recreational activities, all while soaking in the vibrant community atmosphere.
Sikeston Depot Museum: Immerse yourself in local history at the Sikeston Depot Museum. This art museum showcases cultural exhibits that reflect the rich heritage of the area, making it a fascinating stop for history buffs and art lovers alike.
Front Street Studio & Art Gallery: Just 14km from Sikeston, Front Street Studio & Art Gallery is a charming space featuring local artists' works. Explore unique art pieces and engage with the artistic community, enhancing your appreciation of regional culture.
Best time to go to Sikeston
The best time to visit Sikeston is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.
Calendar Month
Temperature
Precipitation
Cloudiness
Occupancy
Pricing
January
36.0°F (2.2°C)
Light Rain
Mostly Sunny
Slightly Low
Slightly Low
February
39.2°F (4.0°C)
Light Rain
Mostly Sunny
Slightly Low
Average
March
49.5°F (9.7°C)
Light Rain
Mostly Sunny
Slightly High
Slightly High
April
58.5°F (14.7°C)
Light Rain
Mostly Sunny
Average
Slightly High
May
68.2°F (20.1°C)
Light Rain
Mostly Sunny
Average
Slightly High
June
77.2°F (25.1°C)
Light Rain
Mostly Sunny
Slightly High
Average
July
79.5°F (26.4°C)
Light Rain
Mostly Sunny
Slightly High
Average
August
77.5°F (25.3°C)
Light Rain
Mostly Sunny
Average
Average
September
72.1°F (22.3°C)
Light Rain
Mostly Sunny
Average
Average
October
60.8°F (16.0°C)
Light Rain
Mostly Sunny
Average
Average
November
48.6°F (9.2°C)
Light Rain
Mostly Sunny
Average
Slightly Low
December
41.2°F (5.1°C)
Light Rain
Mostly Sunny
Slightly Low
Slightly Low
The nearest major airports for your trip to Sikeston
Traveling to Sikeston, Missouri, is convenient with several nearby airports. Jackson, TN (MKL-McKellar-Sipes Regional) is 154km away, with hotels like the 4-star DoubleTree by Hilton and 3-star Residence Inn, both offering comfortable stays. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is only 39km from Sikeston, featuring the Drury Plaza Hotel and Drury Inn & Suites, both rated 3 stars. Veterans Airport of Southern Illinois (MWA) is located 109km away, with options like the Drury Inn & Suites Marion and Holiday Inn Express, both rated 3 stars, ensuring easy access to your destination.
Frequently Asked Questions
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
Where can I learn more about changing or cancelling my trip to Sikeston?
For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.
What's the best budget-friendly hotel in Sikeston?
Where is the best hotel to stay close to Central Park?
Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.
What about the best place to stay close to Sikeston Depot Museum?
Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 16 hotels and other accommodations to choose from. Find out more about Sikeston.
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.