Sikeston, MO

Travel Guide

A tree with sunlight filtering through its leaves, creating a warm glow.
A person walking through a cornfield.
A building with three tall chimneys, surrounded by blooming trees with pink and white flowers.
A sign for Lambert's, a place of worship.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is NT$3,573 per night from Jul 27 to Jul 28
NT$3,573
NT$4,108 total
Jul 27 - Jul 28
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,013 reviews)
"everything was great and super close to lamberts even though i caught a roll to the face it was still awesome 10 out of 10 would do again"

Reviewed on 2026/7/11

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is NT$2,189 per night from Aug 10 to Aug 11
NT$2,189
NT$2,495 total
Aug 10 - Aug 11
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,004 reviews)
"I had a stay at this hotel. The rooms were clean, comfortable, and well maintained. The staff was friendly, professional, and always willing to help. The location was in a convenient place for us to take a quick rest The breakfast was delicious with plenty of options, and the overall atmosphere was ..."

Reviewed on 2026/7/4

Days Inn and Suites by Wyndham Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is NT$2,729 per night from Jul 26 to Jul 27
NT$2,729
NT$3,110 total
Jul 26 - Jul 27
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,005 reviews)
"Stay was okay for a night."

Reviewed on 2026/7/10

Best Western Plus Sikeston I-55
See all 319 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Urban Lofts

Urban Lofts

3 out of 5
102 N Jackson St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Feltz Street Park and Perryville ...
9.4/10 Exceptional! (22 reviews)
"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."

Reviewed on 2026/6/11

Urban Lofts
The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel

2 out of 5
112 W Ste Maries St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and bathrobes. Popular attractions Feltz Street Park and Perryville Country Club are located ...
9.6/10 Exceptional! (4 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. ..."

Reviewed on 2026/6/13

The Atrium - A Boutique Hotel
See all properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sikeston attractions

Sikeston Depot Museum

7.6/10 (57 reviews)
You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.
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