A tree with sunlight filtering through its leaves, creating a warm glow.

Sikeston Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for Sikeston vacation rentals

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

1. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.6 out of 10, Exceptional, (14 reviews)
"Great place to stay"
United States
Matt
The price is NT$2,898
NT$3,318 total
includes taxes & fees
Nov 13 - Nov 14
The Atrium - A Boutique Hotel
A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

2. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
The price is NT$6,625
NT$10,220 total
includes taxes & fees
Nov 13 - Nov 14
Urban Lofts
A large outdoor area with a pond, several wooden cabins, and a road.

3. Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois
3.0 star property
Murphysboro
The price is NT$3,943
NT$7,723 total
includes taxes & fees
Nov 15 - Nov 16
Pet Friendly! Couples Retreat in Southern Illinois
A wooden cabin with a front porch, a staircase, and a door.

4. Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
2.5 star property
Murphysboro
The price is NT$4,141
NT$7,941 total
includes taxes & fees
Nov 22 - Nov 23
Pet Friendly! Countryside Couples Stay in Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Sikeston Hotel Reviews

Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"We really enjoyed the Dog Park as we were traveling with our dogs. The outdoor fire pit was great to sit at on the cool evenings. Breakfast had a variety of options from hot to cold food and diy waffles."
Tonya 2-night trip
Posted 6 hours ago
Hampton Inn Sikeston

Find out more about Sikeston

Search for holiday rentals in Sikeston on Expedia! You can easily find your home rentals, villas, holiday apartments in Sikeston using one of the methods below:

  • View our selection of featured holiday rentals in Sikeston
  • Use the map to find apartments and other holiday homes in the Sikeston neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Sikeston while they last

Look no further and take a look at our great range of rental properties in Sikeston!

Frequently asked questions

Can I find a vacation rental in Sikeston?

Yes, there are vacation rentals close to the most popular local attractions in Sikeston, or you can choose a more remote option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in Sikeston. Make sure you allow time to enjoy the riverfront during your vacation.

What’s there to see and do in Sikeston?

Cultural attractions include Sikeston Depot Museum, whereas Central Park is a spot to enjoy nature. In the larger area, you’ll find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery.

What’s a vacation rental in Sikeston like?

A vacation rental is a private property you can book for a couple of days or more in Sikeston. Vacation rentals feature extras such as kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a small group gathering.