Best Western Plus Sikeston welcomes visitors with a complimentary full breakfast. Enjoy on-site shopping, free WiFi, and an indoor pool. Maintain your fitness routine at the gym. Guests consistently praise the excellent staff and convenient location.
Sikeston is home to Best Western Plus Sikeston I-55. The area's natural beauty can be seen at Mississippi River and Central Park, while Sikeston Depot Museum and Front Street Studio & Art Gallery are cultural highlights. Visit our Sikeston travel guide
120 S Interstate Drive, Sikeston, MO, 63801
What's nearby
Southeast Missouri State University
33 min drive - 60.9 km
City of Miner Convention Center
11 min walk - 1.0 km
Central Park
5 min drive - 5.9 km
Saint Francis Medical Center
28 min drive - 57.1 km
Isle Casino Cape Girardeau
32 min drive - 60.5 km
Getting around
St. Louis Lambert Intl. Airport (STL)
140 min drive
Restaurants
Lambert's Cafe
3 min drive
Buffalo Wild Wings
6 min drive
Burger King
5 min drive
Starbucks
7 min drive
Imo's Pizza
7 min drive
About this property
Best Western Plus Sikeston I-55
Property highlights
Take advantage of free full breakfast, a grocery/convenience store, and shopping on site at Best Western Plus Sikeston I-55. Stay connected with free WiFi in public areas, with speed of 25+ Mbps, and guests can find other amenities such as laundry facilities and a gym.
Additional perks include:
An indoor pool
Free self parking
Express check-out, smoke-free premises, and a computer station
Laundry services, a water dispenser, and an elevator
Guest reviews give top marks for the helpful staff and location
Room features
All 55 rooms offer comforts such as laptop-friendly workspaces and air conditioning, as well as perks like high-speed internet.
Extra conveniences in all rooms include:
Rollaway/extra beds (surcharge) and free cribs/infant beds
Bathrooms with tubs or showers and free toiletries
Wheelchair-accessible parking and van parking available
Food and drink
Free full breakfast available daily 6:00 AM to 9:00 AM
Things to do
Gym
Indoor pool
Shopping
Family friendly
Grocery/convenience store
In-room crib
In-room microwave
Indoor pool
Laundry facilities
Mini-fridge
Rollaway/extra bed (surcharge)
Conveniences
24-hour front desk
Grocery/convenience store
Laundry facilities
Water dispenser
Guest services
Housekeeping (daily)
Business services
24-hour business center
Computer station
Accessibility
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Check-in start time: 3 PM; Check-in end time: anytime
Early check-in subject to availability
Minimum check-in age: 21
Check-out
Check-out before 11 AM
Late check-out subject to availability
Express check-out available
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets allowed for an extra charge of USD 20.00 per pet, per night
Service animals are welcome, and are exempt from fees
Restrictions apply; for more information contact the property at the number on the booking confirmation
Children and extra beds
Children are welcome
Rollaway/extra beds are available for USD 10.0 per stay
Free cribs are available on request at the property
Property payment types
Important information
Optional extras
Fee for in-room wireless internet: USD 1 per stay (rates may vary)
Pet fee: USD 20.00 per pet, per night
Service animals are exempt from fees
Rollaway bed fee: USD 10.0 per stay
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of We Care Clean (Best Western)
Property is also known as
Best Western Plus Hotel Sikeston
Best Western Plus Sikeston
Holiday Inn Express Sikeston Hotel Sikeston
Best Western Plus Sikeston Hotel
Best Western Plus Sikeston Hotel Miner
Best Western Plus Sikeston Miner
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Hotel Best Western Plus Sikeston
Best Western Plus Sikeston Sikeston
Best Western Plus Hotel
Best Western Plus
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Frequently asked questions
Does Best Western Plus Sikeston I-55 have a pool?
Yes, this property has an indoor pool.
How much does it cost to stay at Best Western Plus Sikeston I-55?
As of 2026/3/12, prices found for a 1-night stay for 2 adults at Best Western Plus Sikeston I-55 on 2026/3/26 start from NT$2,591, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Best Western Plus Sikeston I-55 pet-friendly?
Yes, pets are allowed at this property. There's a fee of USD 20.00 per pet, per night. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much is parking?
Self parking is free at this property.
What time is check-in at Best Western Plus Sikeston I-55?
Check-in start time: 3 PM; Check-in end time: anytime.
What time is check-out at Best Western Plus Sikeston I-55?
Check-out is at 11 AM.
Where is Best Western Plus Sikeston I-55 located?
Situated in Sikeston, this hotel is 0.7 mi (1.2 km) from City of Miner Convention Center and within 6 mi (10 km) of Sikeston Depot Museum and Central Park. Front Street Studio & Art Gallery is 9 mi (14.5 km) away.
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Reviews
Best Western Plus Sikeston I-55 Reviews
8.4
Very Good
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
We were travelling through and were pleasantly surprised at how well maintained the hotel was. Also breakfast was great with eggs and biscuits and gravy. Would definitely stay again.
John
Stayed 1 night in Jul 2025
10/10 Excellent
Kenneth
2025/11/10
Liked: Cleanliness, staff & service, amenities
Clean room
Kenneth
Stayed 1 night in Nov 2025
10/10 Excellent
Josh
2025/7/28
Liked: Amenities
The area was clean and in a good area older room but had been renovated comfy bed and the a/c worked really well