Find Business Hotels in Central San Diego, CA

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Our top choices for Central San Diego business-friendly hotels

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.2 out of 10, Wonderful, (1,489 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
United States
Holly
The price is NT$7,197
NT$8,259 total
includes taxes & fees
Feb 26 - Feb 27
Lafayette Hotel & Club

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
Mission Valley
8.0 out of 10, Very Good, (1,023 reviews)
"Great stay"
United States
Viviann
Crowne Plaza San Diego - Mission Valley by IHG

Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town
3.0 star property
Old Town San Diego
8.4 out of 10, Very Good, (1,941 reviews)
"Perfect place to explore Old Town. "
United States
Claudia Matthew
The price is NT$3,746
NT$4,306 total
includes taxes & fees
Mar 1 - Mar 2
Best Western Plus Hacienda Hotel Old Town

Best Western San Diego/Miramar Hotel

Best Western San Diego/Miramar Hotel
2.5 star property
Miramar
7.8 out of 10, Good, (1,213 reviews)
"Clean room and great breakfast buffet."
United States
Danny Bryan
Best Western San Diego/Miramar Hotel

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1,875 reviews)
"Great included breakfast!"
United States
Gina
The price is NT$5,049
NT$6,699 total
includes taxes & fees
Feb 28 - Mar 1
Embassy Suites by Hilton San Diego La Jolla

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
Mission Hills
9.2 out of 10, Wonderful, (1,065 reviews)
"great stay"
United States
Jose
Holiday Inn Express San Diego Airport - Old Town by IHG

Courtyard by Marriott San Diego Central

Courtyard by Marriott San Diego Central
3.0 star property
Kearny Mesa
8.6 out of 10, Excellent, (1,008 reviews)
"Was a great hotel that was decorated perfectl. "
United States
Thomas
Courtyard by Marriott San Diego Central

Homewood Suites by Hilton San Diego Central

Homewood Suites by Hilton San Diego Central
3.0 star property
Scripps Ranch
8.6 out of 10, Excellent, (841 reviews)
"Breakfast and service by the staff are excellent "
United States
Karthik
Homewood Suites by Hilton San Diego Central

Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
2.5 star property
Kearny Mesa
9.0 out of 10, Wonderful, (1,012 reviews)
"Absolutely wonderful hotel. Really great location with a lot of convenient dining and shopping options in the area. "
United States
Maxwell
Hampton Inn San Diego-Kearny Mesa

Fairfield Inn & Suites San Diego Old Town

Fairfield Inn & Suites San Diego Old Town
3.0 star property
Old Town San Diego
8.6 out of 10, Excellent, (1,009 reviews)
"Great location, clean rooms, good breakfast"
United States
Jingyi
Fairfield Inn & Suites San Diego Old Town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Central San Diego Hotel Reviews

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Frequently asked questions

Why book your business-friendly hotel in Central San Diego with Expedia?
Expedia will help you find the ideal business-friendly hotel for your upcoming work trip. From meeting rooms and conference spaces to on-site restaurants and more, our accommodations have all you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Central San Diego?
Click on the "business friendly" filter, located under the "traveler experience" heading, to find cheap business-friendly hotels in Central San Diego. Then fine-tune your search by your nightly budget. Looking for properties away from the center can also help you save.