Central San Diego Vacations

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Where to stay in Central San Diego

Find the best Central San Diego areas and neighborhoods for the activities you enjoy most. Learn more about Central San Diego
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Mission Valley

3 out of top 10 points of interest in this area
4/5(4,999 area reviews)

Boasting major shopping malls like Fashion Valley Mall and Westfield Mission Valley, this area offers entertainment and historic sites such as Mission San Diego de Alcalá and Presidio Park. Easily accessible via the San Diego Trolley system's Green Line.

Find hotels in Mission Valley

Find the Best Central San Diego Vacation Packages

Central San Diego Hotel Deals

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is NT$3,517 per night from Aug 18 to Aug 19
NT$3,517
NT$4,042 total
Aug 18 - Aug 19
includes taxes & fees
8/10 Very Good! (1,917 reviews)
"I think it was a good experience. Rooms were decent, the service is excellent. I will be coming back!"

Reviewed on 2025/8/8

Handlery Hotel
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is NT$4,019 per night from Aug 17 to Aug 18
NT$4,019
NT$4,620 total
Aug 17 - Aug 18
includes taxes & fees
8.6/10 Excellent! (1,158 reviews)
"Overall the hotel it’s nice. Just the room it’s small"

Reviewed on 2025/8/6

Hampton Inn San Diego/Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is NT$3,790 per night from Aug 13 to Aug 14
NT$3,790
NT$4,356 total
Aug 13 - Aug 14
includes taxes & fees
8.4/10 Very Good! (1,468 reviews)
"Customer service, beds and sheets wonderful. Amazing view from room. Good location."

Reviewed on 2025/8/2

Sheraton Mission Valley San Diego Hotel
See all 1,488 properties in Central San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Central San Diego

San Diego Zoo featuring landscape views, zoo animals and a pond

San Diego Zoo

See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Zoo
Balboa Park which includes a pond

Balboa Park

Culture and nature converge in this diverse park located in the heart of the city.

Balboa Park
Nothing like a California sunset.

Hotel Circle

Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and charming cafes in this family-friendly area.

Hotel Circle

Frequently asked questions

How much does a Central San Diego vacation package cost?
Handcraft your Central San Diego vacation package from as low as . Pick from any combination of flights, hotels and rental cars to create the getaway you've been dreaming about for ages. Be sure to add on a few activities!
How do I get a cheap travel package to Central San Diego?
If you love getting an amazing deal, bundle your bookings into a Central San Diego vacation package. Whether you're chasing flights, hotels, rental cars or tours, you can browse and book them all in one place. You'll have plenty of choice at your fingertips too. Expedia has over 550 partner airlines and 1,000,000 properties worldwide to take your pick of. Fly with who you prefer, book a room where you like and save precious money — now that's the perfect getaway!
Where should I stay in Central San Diego?
Travelers come from all corners of the globe to see San Diego Zoo and San Diego Convention Center in Central San Diego. Book a room near these top attractions and visit them at your leisure.
What are the top hotels in Central San Diego?
Get your escape off to an excellent start by booking a stay at We Create A Home Away From Home Near Shopping 15 Minutes From Beach. It's one of most popular hotels in Central San Diego. Another top option is Cottage 1 Br/1 Bath, 500 Sft.
How far in advance should I book my Central San Diego vacation?
It's tricky picking the best time for airfares, but we generally suggest the earlier, the better. Plenty of international flights on Expedia become available to compare up to a year in advance. If you're unable to do so, don't stress. Bargain prices occasionally appear just weeks before departure dates.
What does an Expedia Central San Diego travel package include?
Expedia has all you need to organize your Central San Diego escape, but how you structure your package is entirely up to you. Pick from any combination of rental cars, flights and hotels. Searching for a few activities to keep you busy? Once you've made your booking, you can add them on too. No matter your budget, there's a vacation package to match your needs.
What should I know before booking a Central San Diego travel package?
So many places to go, so many things to experience. With a travel package, you'll be able to cross more of them off your list. Bundle your flights, rental cars and hotels and make big savings.
Can I choose my airline with a Central San Diego Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to take your pick of available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Central San Diego vacation package?
Whether it's your hotel or flight, you can cancel or alter it. Booked your Central San Diego vacation package in the last 24 hours? You may be able to make changes or cancellations at no cost. For bookings made more than 24 hours ago, you may incur a fee from your hotel, airline or car rental company. For more details, browse our Customer Service Portal. We'll help you each step of the way.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.