Serra Mesa, CA

San Diego

A residential area with houses, roads, and a hilly landscape.

Stay near popular Serra Mesa attractions


Serra Mesa Hotel Deals

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is NT$4,570 per night from Nov 22 to Nov 23
NT$4,570
NT$6,432 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is NT$5,317 per night from Nov 22 to Nov 23
NT$5,317
NT$7,738 total
Nov 22 - Nov 23
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (4,584 reviews)
"Staff and amenities were nice. Was somewhat disappointed in the bed mattress. That mattress has seen its time and should be replaced"

Reviewed on 2026/11/3

Hard Rock Hotel San Diego
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is NT$2,942 per night from Dec 3 to Dec 4
NT$2,942
NT$3,382 total
Dec 3 - Dec 4
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (3,032 reviews)
"Overall good hotel. We had 3 good nights in this hotel. The only issue that I can point out was that the windows are old and we could hear people talking next to our room all night. They were outside the hotel but it was loud so we woke up 2 times in the middle if the night. Everything else was ..."

Reviewed on 2026/11/3

Handlery Hotel
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is NT$6,138 per night from Nov 29 to Nov 30
NT$6,138
NT$8,781 total
Nov 29 - Nov 30
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,972 reviews)
"I was pleased with the resort and it exceeded my expectations. Super cute and a nice retreat by the water. I loved all the amenities. It helped to visit after 4th of July, so we avoided some of the overcrowding that could happen. Our space was clean, cozy, and spacious. Our stay was worth every ..."

Reviewed on 2026/11/3

Paradise Point Resort & Spa
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
The price is NT$2,742 per night from Nov 17 to Nov 18
NT$2,742
NT$3,146 total
Nov 17 - Nov 18
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
8/10 Very Good! (3,082 reviews)
"They need to change the shower head. The deadbolt lock isn't locking. The bed needs to be changed. When my partner is moving I can feel it like a wave."

Reviewed on 2026/11/2

California Suites Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundable
The price is NT$2,758 per night from Nov 4 to Nov 5
NT$2,758
NT$3,170 total
Nov 4 - Nov 5
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
7.8/10 Good! (4,042 reviews)
"Best non-resort hotel in SD."

Reviewed on 2026/11/2

Best Western Seven Seas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Nova SD is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.



Serra Mesa, CA