Southwest Florida 5 Stars Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southwest Florida 5 Star Hotels
Our top choices for Southwest Florida 5-star hotels
9.2 out of 10, Wonderful, (459)
"beautiful old world style hotel with modern amenities. Heated pools, great beach side restaurant, fabulous signature restaurant the Grille."
Anthony
The price is NT$37,689
NT$43,754 total
includes taxes & fees
Jan 4 - 2026/1/5
9.2 out of 10, Wonderful, (1003)
"Excellent property and staff"
NINA
The price is NT$20,547
NT$25,261 total
includes taxes & fees
Jan 28 - 2026/1/29
9.4 out of 10, Exceptional, (615)
"Very clean, amazing restaurants to choose fr I highly recommend!"
sebastian
The price is NT$21,972
NT$26,308 total
includes taxes & fees
Jan 4 - 2026/1/5
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
Mary Anne
The price is NT$11,571
NT$14,619 total
includes taxes & fees
Jan 7 - 2026/1/8
6.0 out of 10, (2)
"My wife and I celebrated her 30th birthday a couple weeks ago and were a bit disappointed with the hotel. Our first encounter upon entering the room was a fishy odor and we had to have the room re-cleaned (someone had fish in the mini-fridge). We are avid travelers and spend a lot of time in hotels around the world and we were surprised to find a charge for WiFi service. Especially when free WiFi can be found in the cheapest of motels! The gym is VERY small, and the pools were dirty. We selected...
Jramjohn
The price is NT$44,008
NT$48,848 total
includes taxes & fees
Jan 4 - 2026/1/5
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southwest Florida.
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is NT$14,117 per night from Dec 30 to Dec 31
NT$14,117
NT$17,318 total
Dec 30 - Dec 31
includes taxes & fees
8.8/10 Excellent! (1,724 reviews)
Still don't see what you're looking for?
See all properties in Southwest Florida.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southwest Florida
Amazing beaches, golf courses, and popular sights from Siesta Key Beach to Key West Express—explore Southwest Florida, a destination also known for its island views.
Top Southwest Florida Hotel Reviews
Frequently asked questions
Explore a world of travel with Expedia
- 4 Star Hotels in North Captiva
- Resorts & Hotels with Spas in Southwest Florida
- Luxury Hotels in Bonita Springs
- Hotels with Bars in Southwest Florida
- Hotels near Old Corkscrew Golf Club
- Waterpark Hotels in Southwest Florida
- Pet-Friendly Hotels in Estero
- 4 Star Hotels in Goodland
- 3 Star Hotels in Isles of Capri
- 5 Star Hotels in Cypress Cove
- Cheap Hotels in Bonita Springs
- Luxury Hotels in Southwest Florida
- Hotels near Florida Gulf Coast University
- 4 Star Hotels in Naples
- Luxury Hotels in Estero
- Hotels near Flamingo Island Flea Market
- Hotels near Miromar Outlets
- Adults Only Resorts & in Southwest Florida
- 4 Star Hotels in Grey Oaks
- 4 Star Hotels in Sanibel Captiva Island
- Hotel Wedding Venues Hotels in Bonita Springs
- Beach Hotels in Miromar Lakes
- 5 Star Hotels in Immokalee
- Family Hotels in Estero
- Hotels near Coconut Point Mall
- 4 Star Hotels in Sanibel
- 5 Star Hotels in North Fort Myers
- Condo Rentals in Southwest Florida
- 3 Star Hotels in Ave Maria
- 2 Star Hotels in Grey Oaks
- All-Inclusive Hotel Hotels in Southwest Florida
- Casino Hotels in Southwest Florida
- Resorts & Hotels with Spas in Three Oaks
- 4 Star Hotels in Bonita Springs
- Resorts in Southwest Florida
- 5 Star Hotels in Marco Island
- Waterpark Hotels in Estero
- Golf Hotels in Estero
- Resorts & Hotels with Spas in Miromar Lakes
- 3 Star Hotels in Immokalee
- 5 Star Hotels in Naples
- 5 Star Hotels in North Captiva
- 4 Star Hotels in Cape Coral
- 5 Star Hotels in Village Walk of Bonita Springs
- 5 Star Hotels in Cape Coral
- 5 Star Hotels in Goodland
- 4 Star Hotels in LaBelle
- Flights from Southwest Florida Intl.
- Flights from Pereira (PEI) to Fort Myers (RSW)
- Flights from Manila (MNL) to Fort Myers (RSW)
- Flights from Penneshaw (PEA) to Fort Myers (RSW)
- Flights from Oranjestad (AUA) to Fort Myers (RSW)
- Flights from Smyrna (MQY) to Fort Myers (RSW)
- Flights from Dayton (DAY) to Fort Myers (RSW)
- Flights from Badajoz (BJZ) to Fort Myers (RSW)
- Flights from Riyadh (RUH) to Fort Myers (RSW)
- Flights from Page (PGA) to Fort Myers (RSW)
- Flights from Little Rock (LIT) to Fort Myers (RSW)
- Flights from Cambridge (CBG) to Fort Myers (RSW)
- Flights from Frankfort (FFT) to Fort Myers (RSW)
- Flights from Lisbon (LIS) to Fort Myers (RSW)
- Flights from New York (JFK) to Fort Myers (RSW)
- Flights from St. Louis (STL) to Fort Myers (RSW)
- Flights from Great Harbour Cay (GHC) to Fort Myers (RSW)
- Flights from Estero
- Flights from Venice (VCE) to Fort Myers (RSW)
- Flights from Gatlinburg (GKT) to Fort Myers (RSW)
- Flights from Polokwane (PTG) to Fort Myers (RSW)
- Flights from Galena (GAL) to Fort Myers (RSW)
- Flights from Hanoi (HAN) to Fort Myers (RSW)
- Flights from Frankfurt (FRA) to Fort Myers (RSW)
- Flights from Timmins (YTS) to Fort Myers (RSW)
- Flights from Toronto (YYZ) to Fort Myers (RSW)
- Flights from Sarasota (SRQ) to Fort Myers (RSW)
- Flights from Toronto (YTO) to Fort Myers (RSW)
- Flights from St. George (SGU) to Fort Myers (RSW)
- Flights from Sanday (NDY) to Fort Myers (RSW)
- Flights from Kyiv (IEV) to Fort Myers (RSW)
- Flights from Naples (APF) to Fort Myers (RSW)
- Flights from Atlanta (ATL) to Fort Myers (RSW)
- Flights from Southwest Florida
- Flights from Medicine Hat (YXH) to Fort Myers (RSW)
- Flights from Dayton (MGY) to Fort Myers (RSW)
- Flights from Carlsbad (CLD) to Fort Myers (RSW)
- Flights from Longview (GGG) to Fort Myers (RSW)
- Flights from San Diego (SAN) to Fort Myers (RSW)
- Flights from Aguadilla (BQN) to Fort Myers (RSW)
- Flights to Estero
- Surprice Car Rentals Rental Cars in Southwest Florida Intl.
- Easirent.com Rental Cars in Southwest Florida Intl.
- Enterprise Rental Cars in Southwest Florida
- Car rentals near Stoneybrook Golf Club
- Car rentals near Miromar Outlets
- Car rentals near Coconut Point Mall
- Fox Rental Cars Rental Cars in Southwest Florida Intl.