Bridge over Mississippi River, New Orleans in background

Cairo 2 Stars Hotels

Name: Upscale & Quiet Paducah Retreat on 15 Acres!
Rating: 10

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Our top choices for Cairo 2-star hotels

Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

Lana

NT$2,150 total

includes taxes & fees

Dec 28 - Dec 29

Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

Charleston

Arturo

NT$2,274 total

includes taxes & fees

Dec 24 - Dec 25

Quality Inn Cairo I-57

Cairo

Uma

NT$2,552 total

includes taxes & fees

Jan 3 - 2026/1/4

Desk, iron/ironing board, free WiFi, alarm clocks

Eagle Inn Charleston

Charleston

David

NT$2,094 total

includes taxes & fees

Dec 28 - Dec 29

La Center Motel

La Center

Victoria

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Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Cairo.

Upscale & Quiet Paducah Retreat on 15 Acres!

West Paducah KY

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10/10 Exceptional! (1 review)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town.

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