Find Family Hotels in Upstate South Carolina, SC

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Upstate South Carolina Family Hotels

Next weekend
In two weeks

Our top choices for Upstate South Carolina family-friendly hotels

Hampton Inn Gaffney

Hampton Inn Gaffney
2.5 star property
Gaffney
8.8 out of 10, Excellent, (699 reviews)
The price is NT$2,932
NT$3,196 total
includes taxes & fees
Apr 19 - Apr 20
Hampton Inn Gaffney

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (996 reviews)
The price is NT$4,762
NT$5,285 total
includes taxes & fees
Apr 6 - Apr 7
Clemson University's James F. Martin Inn

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (214 reviews)
  • cleanliness
    Family adventure awaits at this lakeside hotel with spacious accommodations, outdoor pool, and complimentary breakfast.
The price is NT$3,834
NT$4,217 total
includes taxes & fees
Apr 12 - Apr 13
Fairfield Inn & Suites Seneca Clemson Univ Area

Quality Inn Union US Hwy 176

Quality Inn Union US Hwy 176
2.5 star property
Union
7.6 out of 10, Good, (270 reviews)
The price is NT$2,418
NT$2,683 total
includes taxes & fees
May 2 - May 3
Quality Inn Union US Hwy 176

Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
2.5 star property
Gaffney
8.8 out of 10, Excellent, (464 reviews)
The price is NT$2,844
NT$3,100 total
includes taxes & fees
Apr 12 - Apr 13
Holiday Inn Express Gaffney by IHG

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,004 reviews)
The price is NT$3,613
NT$4,010 total
includes taxes & fees
Apr 12 - Apr 13
Comfort Inn & Suites Clemson - University Area

Best Western Spartanburg Northwest

Best Western Spartanburg Northwest
3.0 star property
Spartanburg
8.4 out of 10, Very Good, (865 reviews)
  • cleanliness
    Family-friendly hotel with outdoor pool, premium channels, and proximity to nature preserve offers endless entertainment options.
The price is NT$2,825
NT$3,136 total
includes taxes & fees
Apr 29 - Apr 30
Best Western Spartanburg Northwest

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
2.5 star property
Greenville
9.2 out of 10, Wonderful, (1,439 reviews)
  • cleanliness
    Family vacations flourish at this hotel where kids enjoy a seasonal pool just minutes from science center fun.
The price is NT$2,704
NT$2,974 total
includes taxes & fees
Apr 19 - Apr 20
Best Western Plus Greenville I-385 Inn & Suites

Courtyard by Marriott Greenville Mauldin

Courtyard by Marriott Greenville Mauldin
3.0 star property
Greenville
9.0 out of 10, Wonderful, (327 reviews)
  • cleanliness
    Family-friendly Greenville escape boasts spacious rooms, an inviting outdoor pool, and amenities that delight guests of all ages.
The price is NT$3,483
NT$3,832 total
includes taxes & fees
Apr 12 - Apr 13
Courtyard by Marriott Greenville Mauldin

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (907 reviews)
  • cleanliness
    Family-friendly summer pool days await with free breakfast and nature adventures at this lakeside retreat near Clemson University.
The price is NT$1,707
NT$1,895 total
includes taxes & fees
Apr 19 - Apr 20
Quality Inn Clemson near University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at family-friendly hotels in Upstate South Carolina

Family-friendly hotels with free breakfast in Upstate South Carolina

Family-friendly hotels with pools in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Upstate South Carolina Hotel Reviews

Explore a world of travel with Expedia