Find Resorts & Hotels with Spas in Texas Medical Center, TX

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Check prices for these dates

Tonight
Nov 5 - Nov 6
Tomorrow
Nov 6 - Nov 7
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Our top choices for Texas Medical Center hotels with a spa

A lobby with a marble floor, a reception desk, a seating area with sofas, a fountain, and a staircase.

1. Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,815 reviews)
  • cleanliness
    Luxurious full-service spa retreat with rooftop pool views and designer rooms for a rejuvenating Houston escape.
The price is NT$4,819
NT$5,657 total
includes taxes & fees
Nov 22 - Nov 23
Blossom Hotel Houston, Curio Collection by Hilton
A bathroom with a bathtub, a shower, a vanity with a mirror, and two framed pictures on the wall.

2. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,004 reviews)
  • cleanliness
    Escape to a spa sanctuary with hydromassage showers and heavenly massages at this chic Museum District aparthotel with poolside relaxation.
The price is NT$6,334
NT$8,967 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Zaza Houston Museum District
A reception area with a wooden reception desk, two wicker baskets, and a sign reading "SKYLINE SPA & HEALTH CLUB".

3. Hilton Americas-Houston

Hilton Americas-Houston
4.0 star property
Downtown Houston
9.4 out of 10, Exceptional, (1,891 reviews)
  • cleanliness
    Rejuvenate at this Houston hotel with 4 luxurious spa treatment rooms, sauna, and indoor pool with city views.
The price is NT$5,088
NT$6,019 total
includes taxes & fees
Nov 22 - Nov 23
Hilton Americas-Houston
A modern lobby with a blue carpet, seating area, and large windows.

4. Wyndham Houston at Reliant Park & Medical Center

Wyndham Houston at Reliant Park & Medical Center
3.5 star property
South Main
7.2 out of 10, Good, (1,507 reviews)
The price is NT$3,250
NT$3,803 total
includes taxes & fees
Nov 8 - Nov 9
Wyndham Houston at Reliant Park & Medical Center
A reception area with a marble floor, a wooden reception desk, and a large floral arrangement above the desk.

5. JW Marriott Houston Downtown

JW Marriott Houston Downtown
5.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Downtown escape at this luxury hotel offers a full-service spa with 4 treatment rooms and a health club for ultimate rejuvenation.
The price is NT$8,065
NT$9,666 total
includes taxes & fees
Nov 20 - Nov 21
JW Marriott Houston Downtown
A modern living room with a sofa, green armchairs, a coffee table, and a bookshelf.

6. The Laura Hotel, Houston Downtown, Autograph Collection

The Laura Hotel, Houston Downtown, Autograph Collection
4.5 star property
Downtown Houston
9.2 out of 10, Wonderful, (1,279 reviews)
  • cleanliness
    Rejuvenate at this downtown Houston hotel's full-service spa offering deep-tissue and hot stone massages amid luxurious surroundings.
The price is NT$5,549
NT$7,528 total
includes taxes & fees
Nov 22 - Nov 23
The Laura Hotel, Houston Downtown, Autograph Collection
A modern interior with a reception desk, a large abstract artwork, and a display of products on shelves.

7. Marriott Marquis Houston

Marriott Marquis Houston
4.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1,341 reviews)
  • cleanliness
    Surrender to pure bliss at this contemporary Houston retreat with 7 treatment rooms and 2 sparkling pools, just steps from Discovery Green.
The price is NT$8,832
NT$11,418 total
includes taxes & fees
Nov 22 - Nov 23
Marriott Marquis Houston
A reception area with a modern design, featuring a reception desk, a green sign with the name "MOKARA," and a patterned wall.

8. Omni Houston Hotel

Omni Houston Hotel
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,016 reviews)
  • cleanliness
    Indulge in blissful rejuvenation at this upscale Houston retreat with 7 treatment rooms and outdoor pools nestled among greenery.
The price is NT$5,490
NT$6,519 total
includes taxes & fees
Nov 21 - Nov 22
Omni Houston Hotel
A modern bathroom with a herringbone-patterned wall, a tiled floor, and a built-in shower area.

9. Four Seasons Hotel Houston

Four Seasons Hotel Houston
5.0 star property
Downtown Houston
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Revitalizing spa retreat with Ayurvedic treatments and poolside cabanas awaits at this luxury Houston hotel.
The price is NT$19,207
NT$22,635 total
includes taxes & fees
Nov 23 - Nov 24
Four Seasons Hotel Houston
A modern interior with a city view, a round coffee table, and a wall of neatly organized shelves.

10. Thompson Houston, by Hyatt

Thompson Houston, by Hyatt
4.0 star property
Fourth Ward
9.4 out of 10, Exceptional, (353 reviews)
  • cleanliness
    Experience relaxing spa therapies and luxurious wellness treatments at this art deco hotel near a nature reserve.
The price is NT$8,832
NT$11,735 total
includes taxes & fees
Nov 29 - Nov 30
Thompson Houston, by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Texas Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A hotel lobby with a grand chandelier, a reception desk, and a carpet with the hotel's name.
Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
9.0
Wonderful
3,815 reviews
View
A modern lobby with a blue carpet, seating area, and large windows.
Wyndham Houston at Reliant Park & Medical Center
3.5 star property
7.2
Good
1,507 reviews
View
A spacious living area with a dining table, chairs, and a chandelier.
Hotel Zaza Houston Museum District
4.5 star property
9.2
Wonderful
1,004 reviews
View
A swimming pool with a sunlit water surface and a cityscape in the background.
Hilton Americas-Houston
4.0 star property
9.4
Exceptional
1,891 reviews
View
A modern bar area with a central island, bar stools, and a glass display case filled with bottles.
Omni Houston Hotel
4.0 star property
9.2
Wonderful
1,016 reviews
View

Top Texas Medical Center Hotel Reviews

A lobby with a marble floor, a reception desk, a seating area with sofas, a fountain, and a staircase.
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
Texas Medical Center

10/10 Excellent

Nice hotel with friendly staff, but the area around the hotel is somewhat shady.
United States
Andrew
Reviewed June 24, 2025
Blossom Hotel Houston, Curio Collection by Hilton

Frequently Asked Questions

Looking to vacation at a spa hotel in Texas Medical Center?

Forget the stress of everyday life and book yourself a lush spa hotel. Check out the museums and restaurants in Texas Medical Center—your day trip starts here. Be sure to enjoy the shopping during your stay. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your vacation.

What is the best spa hotel in Texas Medical Center?

Blossom Hotel Houston, Curio Collection by Hilton is a top spa hotel featuring a rooftop terrace, a 24-hour fitness center, an outdoor pool, and a restaurant. Spend an afternoon at the spa where you’ll find facials, Swedish massages, and deep-tissue massages.

How many spa hotels are there in Texas Medical Center?

Among Expedia's 177 accommodation options in Texas Medical Center, there is 1 spa hotel.

What's there to see and do in Texas Medical Center?

Enjoy all that Texas Medical Center has to offer when you visit Houston Zoo, Daikin Park, and Reliant Stadium. If you have extra time while you're in the area, you might want to stop by Toyota Center and Houston Natural Science Museum.

What is a Texas Medical Center spa hotel?

Spa hotels in Texas Medical Center have full on-site spas offering services like couples massages and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.

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