A cityscape with a park, a river, and a large building with a red roof.

Find Resorts & Hotels with Spas in Texas Medical Center, TX

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Texas Medical Center Resorts & Hotels with Spas

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15

Our top choices for Texas Medical Center hotels with a spa

A lobby with a marble floor, a reception desk, a seating area with sofas, a fountain, and a staircase.

1. Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,809 reviews)
"Very nice hotel super clean good location"
United States
Brooke
The price is NT$4,785
NT$5,617 total
includes taxes & fees
Nov 22 - Nov 23
Blossom Hotel Houston, Curio Collection by Hilton
A spacious living area with a dining table, chairs, and a chandelier.

2. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
2.5 km from Texas Medical Center
9.2 out of 10, Wonderful, (1,006 reviews)
"Love this hotel. Been here 4 times. Great pool area, great restaurant, upbeat ambiance. Location is superb for museums and gardens."
United States
Cathy
The price is NT$6,738
NT$9,441 total
includes taxes & fees
Nov 7 - Nov 8
Hotel Zaza Houston Museum District
A large indoor swimming pool with multiple lounge areas and a city view.

3. Hilton Americas-Houston

Hilton Americas-Houston
4.0 star property
6.5 km from Texas Medical Center
9.4 out of 10, Exceptional, (1,886 reviews)
"Delicious breakfast and very clean hotel."
United States
Kalynn
The price is NT$5,052
NT$5,976 total
includes taxes & fees
Nov 22 - Nov 23
Hilton Americas-Houston
A modern lobby with a blue carpet, seating area, and large windows.

4. Wyndham Houston at Reliant Park & Medical Center

Wyndham Houston at Reliant Park & Medical Center
3.5 star property
3.1 km from Texas Medical Center
7.2 out of 10, Good, (1,493 reviews)
"Great stay!!"
United States
Matthew
The price is NT$3,995
NT$4,674 total
includes taxes & fees
Nov 7 - Nov 8
Wyndham Houston at Reliant Park & Medical Center
A modern living room with a sofa, green armchairs, a coffee table, and a bookshelf.

5. The Laura Hotel, Houston Downtown, Autograph Collection

The Laura Hotel, Houston Downtown, Autograph Collection
4.5 star property
Houston Central Business District, 6.5 km from Texas Medical Center
9.2 out of 10, Wonderful, (1,273 reviews)
"Clean spacious rooms great location excellent breakfast"
United States
Giulliana
The price is NT$5,509
NT$7,474 total
includes taxes & fees
Nov 22 - Nov 23
The Laura Hotel, Houston Downtown, Autograph Collection
A spa sign with 'SPA' and 'BYJW' on a wall, a large vertical wooden panel with a green moss-like texture, and a person carrying a tray.

6. JW Marriott Houston Downtown

JW Marriott Houston Downtown
5.0 star property
Houston Central Business District, 6.9 km from Texas Medical Center
9.0 out of 10, Wonderful, (1,000 reviews)
"The hotel was clean, and the staff were great. Perfect location to walk around downtown."
United States
Alyssa
The price is NT$8,008
NT$9,598 total
includes taxes & fees
Nov 7 - Nov 8
JW Marriott Houston Downtown
A modern hotel room with a sofa, a small table, and a lamp.

7. Marriott Marquis Houston

Marriott Marquis Houston
4.0 star property
6.9 km from Texas Medical Center
9.0 out of 10, Wonderful, (1,335 reviews)
"Great room great service great experience"
United States
Jason
The price is NT$8,769
NT$11,337 total
includes taxes & fees
Nov 22 - Nov 23
Marriott Marquis Houston
A reception area with a modern design, featuring a reception desk, a green sign with the name "MOKARA," and a patterned wall.

8. Omni Houston Hotel

Omni Houston Hotel
4.0 star property
8.8 km from Texas Medical Center
9.2 out of 10, Wonderful, (1,012 reviews)
"Great location"
United States
Thomas
The price is NT$5,451
NT$6,473 total
includes taxes & fees
Nov 21 - Nov 22
Omni Houston Hotel
A modern lobby with a central reception desk, a staircase, and a mezzanine level with a railing.

9. Thompson Houston, by Hyatt

Thompson Houston, by Hyatt
4.0 star property
6.6 km from Texas Medical Center
9.4 out of 10, Exceptional, (350 reviews)
"Everything was amazing including the view of the room"
United States
Ray Xavier
The price is NT$8,769
NT$11,652 total
includes taxes & fees
Nov 29 - Nov 30
Thompson Houston, by Hyatt
A modern building entrance with a black car parked in front.

10. Four Seasons Hotel Houston

Four Seasons Hotel Houston
5.0 star property
Houston Central Business District, 6.6 km from Texas Medical Center
9.2 out of 10, Wonderful, (1,001 reviews)
"Loved it and will be back"
United States
Khiana
The price is NT$19,070
NT$22,474 total
includes taxes & fees
Nov 23 - Nov 24
Four Seasons Hotel Houston
A modern spa area with a hot tub, lounge chairs, and a large mirror.

11. The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston
5.0 star property
The Galleria, 7.9 km from Texas Medical Center
9.6 out of 10, Exceptional, (1,000 reviews)
"The hotel service was absolutely beautiful, and the accommodations were of the highest quality."
United States
Michael
The price is NT$17,179
NT$20,100 total
includes taxes & fees
Nov 26 - Nov 27
The Post Oak Hotel at Uptown Houston
A grand staircase with a green garland and golden bows, flanked by wooden paneling and framed artwork on the walls.

12. La Colombe d'Or Hotel

La Colombe d'Or Hotel
5.0 star property
Montrose, 4.3 km from Texas Medical Center
9.4 out of 10, Exceptional, (221 reviews)
"Excellent place to stay"
United States
Keeshaun
The price is NT$13,561
NT$15,866 total
includes taxes & fees
Nov 22 - Nov 23
La Colombe d'Or Hotel
A hotel room with two sofas, a side table, a lamp, and a large window with curtains.

13. The Houstonian Hotel, Club & Spa

The Houstonian Hotel, Club & Spa
4.5 star property
Greater Uptown, 9.4 km from Texas Medical Center
9.6 out of 10, Exceptional, (1,001 reviews)
"over the top.....crisp clean bedding just like new... staff was fabulous....spa was outstanding... can't wait to go back...."
United States
Marylee
The price is NT$16,400
NT$19,284 total
includes taxes & fees
Nov 29 - Nov 30
The Houstonian Hotel, Club & Spa
A cozy seating area with a cushioned sofa, two wicker chairs, a round table, and a decorative wall with a geometric pattern.

14. Hotel ZaZa Houston Memorial City

Hotel ZaZa Houston Memorial City
4.0 star property
Memorial City, 15.9 km from Texas Medical Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Beautiful hotel, great place to stay!"
United States
Amanda
The price is NT$5,615
NT$8,095 total
includes taxes & fees
Nov 22 - Nov 23
Hotel ZaZa Houston Memorial City
A spacious lobby with a central seating area, a bar, and a chandelier.

15. Hotel ICON Autograph Collection by Marriott

Hotel ICON Autograph Collection by Marriott
4.0 star property
Downtown Houston, 7.5 km from Texas Medical Center
9.2 out of 10, Wonderful, (1,000 reviews)
"Great location and staff"
United States
Madison
The price is NT$5,183
NT$6,064 total
includes taxes & fees
Nov 8 - Nov 9
Hotel ICON Autograph Collection by Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Texas Medical Center

Pool
Breakfast included

Top Texas Medical Center Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Texas Medical Center?
Forget the stress of everyday life and book yourself a lush spa hotel. Check out the museums and restaurants in Texas Medical Center—your day trip starts here. Be sure to enjoy the shopping during your stay. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Texas Medical Center?
Blossom Hotel Houston, Curio Collection by Hilton is a top spa hotel featuring a rooftop terrace, a 24-hour fitness center, an outdoor pool, and a restaurant. Spend an afternoon at the spa where you'll find facials, Swedish massages, and deep-tissue massages.
How many spa hotels are there in Texas Medical Center?
Among Expedia's 177 accommodation options in Texas Medical Center, there is 1 spa hotel.
What's there to see and do in Texas Medical Center?
Enjoy all that Texas Medical Center has to offer when you visit Houston Zoo, Daikin Park, and Reliant Stadium. If you have extra time while you're in the area, you might want to stop by Toyota Center and Houston Natural Science Museum.
What is a Texas Medical Center spa hotel?
Spa hotels in Texas Medical Center have full on-site spas offering services like couples massages and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.

Explore a world of travel with Expedia