Find Resorts & Hotels with Spas in Texas Medical Center, TX

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Check prices for these dates

Tonight
Nov 11 - Nov 12
Tomorrow
Nov 12 - Nov 13
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

Our top choices for Texas Medical Center hotels with a spa

A lobby with a marble floor, a reception desk, a seating area with sofas, a fountain, and a staircase.

1. Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,826 reviews)
  • cleanliness
    Luxurious full-service spa retreat with rooftop pool views and designer rooms for a rejuvenating Houston escape.
The price is NT$4,818
NT$5,655 total
includes taxes & fees
Nov 27 - Nov 28
Blossom Hotel Houston, Curio Collection by Hilton
A bathroom with a bathtub, a shower, a vanity with a mirror, and two framed pictures on the wall.

2. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,014 reviews)
  • cleanliness
    Escape to a spa sanctuary with hydromassage showers and heavenly massages at this chic Museum District aparthotel with poolside relaxation.
The price is NT$6,332
NT$8,965 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Zaza Houston Museum District
A reception area with a wooden reception desk, two wicker baskets, and a sign reading "SKYLINE SPA & HEALTH CLUB".

3. Hilton Americas-Houston

Hilton Americas-Houston
4.0 star property
Downtown Houston
9.4 out of 10, Exceptional, (1,899 reviews)
  • cleanliness
    Rejuvenate at this Houston hotel with 4 luxurious spa treatment rooms, sauna, and indoor pool with city views.
The price is NT$5,087
NT$6,017 total
includes taxes & fees
Nov 24 - Nov 25
Hilton Americas-Houston
A modern lobby with a blue carpet, seating area, and large windows.

4. Wyndham Houston at Reliant Park & Medical Center

Wyndham Houston at Reliant Park & Medical Center
3.5 star property
South Main
7.2 out of 10, Good, (1,515 reviews)
The price is NT$4,022
NT$4,706 total
includes taxes & fees
Nov 17 - Nov 18
Wyndham Houston at Reliant Park & Medical Center
A reception area with a marble floor, a wooden reception desk, and a large floral arrangement above the desk.

5. JW Marriott Houston Downtown

JW Marriott Houston Downtown
5.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Downtown escape at this luxury hotel offers a full-service spa with 4 treatment rooms and a health club for ultimate rejuvenation.
The price is NT$8,063
NT$9,664 total
includes taxes & fees
Nov 20 - Nov 21
JW Marriott Houston Downtown
A modern living room with a sofa, green armchairs, a coffee table, and a bookshelf.

6. The Laura Hotel, Houston Downtown, Autograph Collection

The Laura Hotel, Houston Downtown, Autograph Collection
4.5 star property
Downtown Houston
9.2 out of 10, Wonderful, (1,282 reviews)
  • cleanliness
    Rejuvenate at this downtown Houston hotel's full-service spa offering deep-tissue and hot stone massages amid luxurious surroundings.
The price is NT$5,547
NT$7,526 total
includes taxes & fees
Nov 24 - Nov 25
The Laura Hotel, Houston Downtown, Autograph Collection
A reception area with a modern design, featuring a reception desk, a green sign with the name "MOKARA," and a patterned wall.

7. Omni Houston Hotel

Omni Houston Hotel
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,019 reviews)
  • cleanliness
    Indulge in blissful rejuvenation at this upscale Houston retreat with 7 treatment rooms and outdoor pools nestled among greenery.
The price is NT$5,488
NT$6,518 total
includes taxes & fees
Nov 21 - Nov 22
Omni Houston Hotel
A modern interior with a city view, a round coffee table, and a wall of neatly organized shelves.

8. Thompson Houston, by Hyatt

Thompson Houston, by Hyatt
4.0 star property
Fourth Ward
9.4 out of 10, Exceptional, (354 reviews)
  • cleanliness
    Experience relaxing spa therapies and luxurious wellness treatments at this art deco hotel near a nature reserve.
The price is NT$7,957
NT$10,714 total
includes taxes & fees
Nov 29 - Nov 30
Thompson Houston, by Hyatt
A modern interior with a reception desk, a large abstract artwork, and a display of products on shelves.

9. Marriott Marquis Houston

Marriott Marquis Houston
4.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1,345 reviews)
  • cleanliness
    Surrender to pure bliss at this contemporary Houston retreat with 7 treatment rooms and 2 sparkling pools, just steps from Discovery Green.
The price is NT$8,829
NT$11,415 total
includes taxes & fees
Nov 24 - Nov 25
Marriott Marquis Houston
A modern spa area with a hot tub, lounge chairs, and a large mirror.

10. The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston
5.0 star property
The Galleria
9.6 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Experience upscale pampering at this luxury Houston hotel with couples' spa rooms and poolside cabanas for rejuvenation.
The price is NT$17,298
NT$20,238 total
includes taxes & fees
Nov 26 - Nov 27
The Post Oak Hotel at Uptown Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Texas Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A hotel lobby with a grand chandelier, a reception desk, and a carpet with the hotel's name.
Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
9.0
Wonderful
3,826 reviews
View
A spacious living area with a dining table, chairs, and a chandelier.
Hotel Zaza Houston Museum District
4.5 star property
9.2
Wonderful
1,014 reviews
View
A modern lobby with a blue carpet, seating area, and large windows.
Wyndham Houston at Reliant Park & Medical Center
3.5 star property
7.2
Good
1,515 reviews
View
A swimming pool with a sunlit water surface and a cityscape in the background.
Hilton Americas-Houston
4.0 star property
9.4
Exceptional
1,899 reviews
View
A modern bar area with a central island, bar stools, and a glass display case filled with bottles.
Omni Houston Hotel
4.0 star property
9.2
Wonderful
1,019 reviews
View

Top Texas Medical Center Hotel Reviews

A lobby with a marble floor, a reception desk, a seating area with sofas, a fountain, and a staircase.
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
Texas Medical Center

10/10 Excellent

Nice hotel with friendly staff, but the area around the hotel is somewhat shady.
United States
Andrew
Reviewed June 24, 2025
Blossom Hotel Houston, Curio Collection by Hilton

Frequently Asked Questions

Looking to vacation at a spa hotel in Texas Medical Center?

Forget the stress of everyday life and book yourself a lush spa hotel. Check out the museums and restaurants in Texas Medical Center—your day trip starts here. Be sure to enjoy the shopping during your stay. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your vacation.

What is the best spa hotel in Texas Medical Center?

Blossom Hotel Houston, Curio Collection by Hilton is a top spa hotel featuring a rooftop terrace, a 24-hour fitness center, an outdoor pool, and a restaurant. Spend an afternoon at the spa where you’ll find facials, Swedish massages, and deep-tissue massages.

How many spa hotels are there in Texas Medical Center?

Among Expedia's 177 accommodation options in Texas Medical Center, there is 1 spa hotel.

What's there to see and do in Texas Medical Center?

Enjoy all that Texas Medical Center has to offer when you visit Houston Zoo, Daikin Park, and Reliant Stadium. If you have extra time while you're in the area, you might want to stop by Toyota Center and Houston Natural Science Museum.

What is a Texas Medical Center spa hotel?

Spa hotels in Texas Medical Center have full on-site spas offering services like couples massages and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.

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