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Check availability on Southeast Missouri Business Hotels

Tonight
Oct 19 - Oct 20
Tomorrow
Oct 20 - Oct 21
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Southeast Missouri business-friendly hotels

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a stove, and a granite countertop.
A bathroom with a white sink, a large mirror, a hairdryer, a coffee maker, and a microwave.
A building with a red awning labeled "Shepherd Mountain Inn."
A compact kitchen with wooden cabinets, a stainless steel refrigerator, and a microwave.

1. Shepherd Mountain Inn

Shepherd Mountain Inn
Ironton
United States
Michael
NT$3,995
NT$4,364 total
includes taxes & fees
Oct 20 - Oct 21
Shepherd Mountain Inn
A motel with a covered entrance, a flag, and a phone number.
A living room with a black leather sofa, a wooden coffee table with a vase of flowers, a green potted plant, and a lamp.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom.
A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.

2. Madison Inn Lodge

Madison Inn Lodge
Fredericktown
United States
Bawan
NT$2,868
NT$3,132 total
includes taxes & fees
Oct 20 - Oct 21
Madison Inn Lodge
A modern living room with a sectional sofa, a coffee table, and a dining area with chairs and a table.
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and potted plants.
A hotel room with a bed, a sofa, a desk, and a chair.
A hotel lobby with a central reception desk, multiple seating areas, and a tiled floor.

3. Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
Farmington
United States
Sheila
NT$3,823
NT$4,372 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express & Suites Farmington by IHG
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.
A reception area with a wooden counter, a coffee machine, and a display of pastries.

4. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
ELAINE
NT$3,140
NT$3,547 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott Poplar Bluff
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A modern bathroom with a bathtub, a window with curtains, and a view of a green landscape.
A spacious hotel lobby with a dining area, kitchen, and large windows.

5. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
United States
CURTIS
NT$3,277
NT$3,748 total
includes taxes & fees
Nov 19 - Nov 20
Crown Pointe Lodge, BW Signature Collection
A modern kitchen with a coffee machine, a refrigerator, and a microwave.
A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.
A hotel room with a large bed, a smaller bed, a nightstand with a lamp, and two large framed pictures on the wall.
A laundry room with a front-loading washer and dryer, a door, and a light fixture.

6. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
United States
Marisa
NT$1,928
NT$2,205 total
includes taxes & fees
Oct 30 - Oct 31
Super 8 by Wyndham Farmington
A spacious lobby with a reception desk, seating area, and large windows.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.
An indoor swimming pool with a clear view of the outside through large windows.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.

7. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Dean
NT$3,045
NT$3,441 total
includes taxes & fees
Oct 25 - Oct 26
Drury Inn & Suites Poplar Bluff
An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.
A modern hotel lobby with multiple seating areas, a large flat-screen TV mounted on the wall, and a visible exit sign.
A hotel room with a wooden desk, a chair, a television, a microwave, and a minibar.
A reception desk with a wooden panel design, a bicycle mounted on the wall, and a sign reading "Hilton Honors".

8. Hampton Inn Farmington

Hampton Inn Farmington
Farmington
United States
Charlie
NT$3,305
NT$3,780 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn Farmington
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A hotel room with a large bed, two sofas, a desk with a lamp, a microwave, and a TV.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.

9. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
Canada
Kim
NT$1,737
NT$1,986 total
includes taxes & fees
Nov 15 - Nov 16
Baymont Inn and Suites by Wyndham Farmington, MO
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

10. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
NT$3,277
NT$3,697 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Cape Girardeau
View all properties

Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Stayed here for a long weekend motorcycle trip. The hotel is conveniently located near many shopping and dining choices. The room was basic but clean and quiet, and lots of channels on the tv! Staff were super friendly and helpful. I will definitely stay here again the next time I am in Cape Girardeau."
Robert 3-night trip
Posted 1 hour ago
Pear Tree Inn Cape Girardeau West
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"Breakfast was great. Staff was helpful."
Michael 1-night trip
Posted 6 hours ago
Hampton Inn Poplar Bluff
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

8/10 Good
"Room was clean, but humid. Breakfast was standard continental. Staff was nice. Good place to stay on a road trip or for work."
Kyle 4-night trip
Posted 14 hours ago
Baymont Inn and Suites by Wyndham Farmington, MO
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

8/10 Good
"Group of patrons were extremely loud at both dinner and breakfast was nnoi enjoyable n"
Patricia 1-night trip
Posted 19 hours ago
Drury Inn & Suites Hayti Caruthersville
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."
John 3-night trip
Posted 6 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"good, clean, affordable :)"
Nicholas 1-night trip
Posted 6 days ago
Super 8 by Wyndham Sikeston/Miner Area

Frequently asked questions

How much do business-friendly hotels in Southeast Missouri cost?
Rates for business hotels in Southeast Missouri range between NT$1,986 and NT$4,372 per night. No matter your budget, Expedia is here to help you find the perfect place to get the job done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southeast Missouri?
Southeast Missouri has multiple business-friendly hotels with a total average guest review rating of 8.5. Attending a work-related event in Cape Girardeau? Hampton Inn Cape Girardeau I 55 East is a 2.5-stars stay that comes highly recommended by corporate travelers and includes a dining venue and a terrace. Another excellent choice for a business trip is Drury Plaza Hotel Cape Girardeau Conference Center. Also in Cape Girardeau, it has a 3-stars rating and amenities such as a swimming pool and a restaurant.
How many business-friendly hotels are there in Southeast Missouri?
Southeast Missouri has 50 business-friendly hotels to pick from. Whether you're meeting with new clients or working remotely, these stays come with the services and amenities you need to be productive.
What are the best cheap business-friendly hotels in Southeast Missouri?
When you're on the road for work in Southeast Missouri, Expedia will help you find the ideal business-friendly hotel. Hampton Inn Cape Girardeau I 55 East is a budget pick in Cape Girardeau. A dining venue and a swimming pool are some of its many amenities. Seeking affordable stays in Sikeston? Pear Tree Inn Sikeston is recommended by many corporate travelers. It offers conveniences that make it easy to both work and play, such as a swimming pool and a spa tub. Business-friendly hotels in Southeast Missouri start at just NT$1,986 a night. You'll find tons of fabulous and free attractions wherever you're off to in Southeast Missouri. If you're meeting with clients in Cape Girardeau, try to make time in your schedule for Hunter Valley Winery. You can also see the sights without spending a penny in Sikeston. Sikeston Depot Museum is one of the most popular free things to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southeast Missouri that are also business friendly?
There sure are. Whether you're searching for a stay in Southeast Missouri with a conference room or a quiet space to work alone, con espacio para trabajar Expedia's got you sorted. Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau is a fantastic choice. This 3-stars business and family-friendly option comes with all the necessary conveniences, like complimentary breakfast and housekeeping services. Pear Tree Inn Cape Girardeau West is another option in Cape Girardeau where corporate travelers can get some work done with the family in tow. Complimentary breakfast and a laundry service are among the many amenities at this 2.5-stars hotel. When you've finished work, it's time to discover Cape Girardeau with the kids. Popular family-friendly attractions include Cape Splash Family Aquatic Center and Lazy L Safari Park.
Why book your business-friendly hotel in Southeast Missouri with Expedia?
Expedia is here to help you find an ideal business-friendly hotel when work takes you away from home. From meeting rooms and conference spaces to gyms and on-site restaurants, our stays have all the amenities you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Southeast Missouri?
Select the "business friendly" filter, located under the "traveler experience" heading, to find cheap business-friendly hotels in Southeast Missouri. Then fine-tune your search by your per-night budget. Basing yourself outside the city center is another easy way to save.
What is there to do in Southeast Missouri near my business-friendly hotel?
The most important accessory for your Southeast Missouri work visit is an epic itinerary for your downtime! Isle Casino Cape Girardeau, Show Me Center and Riverfront Park are among the top sights if you're headed to Cape Girardeau. Sikeston is also home to terrific attractions, such as Sikeston Depot Museum, Central Park and The Book Bug.

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