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Check availability on Southeast Missouri Business Hotels

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Southeast Missouri business-friendly hotels

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a stove, and a granite countertop.

1. Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.2 out of 10, Wonderful, (337 reviews)
"Clean room, wifi easy to connect to, parking right in front."
United States
Jonathan
The price is NT$3,998
NT$4,366 total
includes taxes & fees
Oct 30 - Oct 31
Shepherd Mountain Inn
A motel with a covered entrance, a flag, and a phone number.

2. Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (314 reviews)
"Nice and clean friendly staff"
United States
Bawan
The price is NT$2,756
NT$3,010 total
includes taxes & fees
Nov 2 - Nov 3
Madison Inn Lodge
A reception area with a modern design, featuring a decorative wall piece, a small table with a bowl, and a patterned partition.

3. Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (442 reviews)
"Room was ready, very clean and breakfast very good"
United States
Sheila
The price is NT$3,599
NT$4,160 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express & Suites Farmington by IHG
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

4. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (975 reviews)
"Everything was great- breakfast, cleanliness, price— will stay there again"
United States
ELAINE
The price is NT$3,142
NT$3,549 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Poplar Bluff
A spacious lobby with a reception desk, seating area, and large windows.

5. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean, great food, excellent staff."
United States
Dean
The price is NT$2,918
NT$3,296 total
includes taxes & fees
Nov 5 - Nov 6
Drury Inn & Suites Poplar Bluff
A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.

6. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very good, (690 reviews)
"Clean nice staff are great"
United States
Marisa
The price is NT$1,929
NT$2,206 total
includes taxes & fees
Nov 8 - Nov 9
Super 8 by Wyndham Farmington
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.

7. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,002 reviews)
"Our room was spacious, clean and the bed was super comfortable!"
Canada
Kim
The price is NT$1,764
NT$2,017 total
includes taxes & fees
Nov 5 - Nov 6
Baymont Inn and Suites by Wyndham Farmington, MO
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.

8. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
8.8 out of 10, Excellent, (699 reviews)
"Enjoyed the very clean modern room and the nice view of the golf course. Great place to relax in Farmington"
United States
CURTIS
The price is NT$3,252
NT$3,719 total
includes taxes & fees
Oct 31 - Nov 1
Crown Pointe Lodge, BW Signature Collection
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

9. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (239 reviews)
"Great hotel…!!"
United States
Carlos
The price is NT$3,279
NT$3,700 total
includes taxes & fees
Nov 5 - Nov 6
Fairfield Inn & Suites by Marriott Cape Girardeau
A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.

10. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
7.8 out of 10, Good, (1,001 reviews)
"When we checked in on Friday night the desk clerk couldn’t have been more welcoming. It had been a long day and her smile was infectious. The property definitely needs some renovations but if you can get by that it was fine. One suggestion is to get sheets that fit the bed. We would most likely stay again."
United States
Ronald
The price is NT$2,728
NT$3,120 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeast Missouri Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"Very clean room and breakfast was alright."
Debra 2-night trip
Posted 3 hours ago
Hampton Inn Poplar Bluff

Frequently asked questions

How much do business-friendly hotels in Southeast Missouri cost?
Rates for business hotels in Southeast Missouri range between NT$2,017 and NT$4,366 per night. No matter your budget, Expedia is here to help you find the perfect place to get the job done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southeast Missouri?
Southeast Missouri has multiple business-friendly hotels with a total average guest review rating of 8.5. Attending a work-related event in Cape Girardeau? Hampton Inn Cape Girardeau I 55 East is a 2.5-stars stay that comes highly recommended by corporate travelers and includes a dining venue and a terrace. Another excellent choice for a business trip is Drury Plaza Hotel Cape Girardeau Conference Center. Also in Cape Girardeau, it has a 3-stars rating and amenities such as a swimming pool and a restaurant.
How many business-friendly hotels are there in Southeast Missouri?
Southeast Missouri has 50 business-friendly hotels to pick from. Whether you're meeting with new clients or working remotely, these stays come with the services and amenities you need to be productive.
What are the best cheap business-friendly hotels in Southeast Missouri?
When you're on the road for work in Southeast Missouri, Expedia will help you find the ideal business-friendly hotel. Hampton Inn Cape Girardeau I 55 East is a budget pick in Cape Girardeau. A dining venue and a swimming pool are some of its many amenities. Seeking affordable stays in Sikeston? Pear Tree Inn Sikeston is recommended by many corporate travelers. It offers conveniences that make it easy to both work and play, such as a swimming pool and a spa tub. Business-friendly hotels in Southeast Missouri start at just NT$2,017 a night. You'll find tons of fabulous and free attractions wherever you're off to in Southeast Missouri. If you're meeting with clients in Cape Girardeau, try to make time in your schedule for Hunter Valley Winery. You can also see the sights without spending a penny in Sikeston. Sikeston Depot Museum is one of the most popular free things to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southeast Missouri that are also business friendly?
There sure are. Whether you're searching for a stay in Southeast Missouri with a conference room or a quiet space to work alone, con espacio para trabajar Expedia's got you sorted. Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau is a fantastic choice. This 3-stars business and family-friendly option comes with all the necessary conveniences, like complimentary breakfast and housekeeping services. Pear Tree Inn Cape Girardeau West is another option in Cape Girardeau where corporate travelers can get some work done with the family in tow. Complimentary breakfast and a laundry service are among the many amenities at this 2.5-stars hotel. When you've finished work, it's time to discover Cape Girardeau with the kids. Popular family-friendly attractions include Cape Splash Family Aquatic Center and Lazy L Safari Park.
Why book your business-friendly hotel in Southeast Missouri with Expedia?
Expedia is here to help you find an ideal business-friendly hotel when work takes you away from home. From meeting rooms and conference spaces to gyms and on-site restaurants, our stays have all the amenities you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Southeast Missouri?
Select the "business friendly" filter, located under the "traveler experience" heading, to find cheap business-friendly hotels in Southeast Missouri. Then fine-tune your search by your per-night budget. Basing yourself outside the city center is another easy way to save.
What is there to do in Southeast Missouri near my business-friendly hotel?
The most important accessory for your Southeast Missouri work visit is an epic itinerary for your downtime! Isle Casino Cape Girardeau, Show Me Center and Riverfront Park are among the top sights if you're headed to Cape Girardeau. Sikeston is also home to terrific attractions, such as Sikeston Depot Museum, Central Park and The Book Bug.

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