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Compare 1,602 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Postcard Cabins Lake Hartwell

2.0 star property
9.8 out of 10, Exceptional, (23)
"It was perfect very clean everything was well thought out using the space very efficiently. Will stay again. It was quiet and a wonderful getaway with beautiful scenery! The big window and amazing bed had the best sleep.."
The price is NT$2,670
NT$4,091 total
includes taxes & fees
Aug 21 - Aug 22
Postcard Cabins Lake Hartwell

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (991)
"Great place to stay in Clemson"
The price is NT$3,270
NT$4,099 total
includes taxes & fees
Aug 20 - Aug 21
Lakeside Lodge Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (184)
"Beautiful clean hotel. Staff was very welcoming. Breakfast area was very clean with many options. The river view is so beautiful. "
The price is NT$4,169
NT$4,586 total
includes taxes & fees
Aug 20 - Aug 21
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (627)
"Service was excellent "
The price is NT$3,783
NT$4,162 total
includes taxes & fees
Aug 28 - Aug 29
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (693)
"The property was near the area that I needed to be in. It has ample shops and restaurants in the area "
The price is NT$2,119
NT$2,331 total
includes taxes & fees
Aug 24 - Aug 25
Days Inn by Wyndham Seneca / Clemson Area

Tru by Hilton Seneca Clemson

2.5 star property
9.2 out of 10, Wonderful, (760)
"Staff and property were top-notch! "
The price is NT$3,289
NT$3,618 total
includes taxes & fees
Aug 31 - Sep 1
Tru by Hilton Seneca Clemson

Quality Inn Seneca Clemson Area US-123

2.5 star property
8.0 out of 10, Very Good, (632)
"Ok hotel for a quick stay "
The price is NT$2,538
NT$3,093 total
includes taxes & fees
Aug 27 - Aug 28
Quality Inn Seneca Clemson Area US-123

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (601)
"We liked the location. It was easy to explore Lake Keowee from here. The blackout window shades were nice too! The room was so humid that it even made the sheets feel damp. "
The price is NT$3,038
NT$3,342 total
includes taxes & fees
Sep 14 - Sep 15
Best Western Seneca-Clemson

Woodspring Suites Anderson North I-85

2.5 star property
7.0 out of 10, Good, (19)
"Very nice and clean property. Staff was so nice and helpful. Made check in so easy"
The price is NT$2,373
NT$2,634 total
includes taxes & fees
Aug 20 - Aug 21
Woodspring Suites Anderson North I-85

Inn @ Clemson

2.5 star property
8.0 out of 10, Very Good, (1011)
"It was very clean. A nice place to stay "
The price is NT$2,670
NT$2,963 total
includes taxes & fees
Sep 1 - Sep 2
Inn @ Clemson

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
8.2 out of 10, Very Good, (1015)
"The hotel was very quiet, clean and staff was very friendly!"
The price is NT$3,162
NT$3,509 total
includes taxes & fees
Aug 21 - Aug 22
Best Western Plus Clemson Hotel & Conference Center

Days Inn by Wyndham Anderson

2.0 star property
7.4 out of 10, Good, (1010)
"Great stay "
The price is NT$1,810
NT$2,009 total
includes taxes & fees
Aug 31 - Sep 1
Days Inn by Wyndham Anderson

Comfort Inn & Suites Clemson - University Area

2.5 star property
8.2 out of 10, Very Good, (1014)
"Awesome place to stay"
The price is NT$3,038
NT$3,372 total
includes taxes & fees
Sep 13 - Sep 14
Comfort Inn & Suites Clemson - University Area

Baymont by Wyndham Anderson Clemson

2.5 star property
7.0 out of 10, Good, (812)
"Excellent stay "
The price is NT$2,170
NT$2,409 total
includes taxes & fees
Aug 27 - Aug 28
Baymont by Wyndham Anderson Clemson

Quality Inn Clemson near University

2.5 star property
7.0 out of 10, Good, (859)
"Great customer service "
The price is NT$1,739
NT$1,930 total
includes taxes & fees
Aug 25 - Aug 26
Quality Inn Clemson near University

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
9.0 out of 10, Wonderful, (558)
"My daughter and I stayed at the property for one night, as we traveled back home. The room was wonderfully clean, the beds comfortable, and the front desk staff was warm and accommodating. I noticed that the hotel even offered board games to play with friends or family. "
The price is NT$3,090
NT$3,429 total
includes taxes & fees
Sep 1 - Sep 2
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Comfort Suites Anderson-Clemson

2.5 star property
8.4 out of 10, Very Good, (995)
"RESTAURANTS, HOTEL WAS GREAT STAFF WAS AWESOME I WOULD DEFINITELY RECOMMEND. "
The price is NT$3,348
NT$3,716 total
includes taxes & fees
Sep 7 - Sep 8
Comfort Suites Anderson-Clemson

Country Inn & Suites by Radisson, Anderson, SC

2.5 star property
8.4 out of 10, Very Good, (1001)
"It was a good place to stay good people "
The price is NT$3,277
NT$3,638 total
includes taxes & fees
Aug 22 - Aug 23
Country Inn & Suites by Radisson, Anderson, SC

Baymont by Wyndham Easley/Greenville

2.5 star property
7.2 out of 10, Good, (689)
"Staff was very friendly and helpful."
The price is NT$2,406
NT$2,670 total
includes taxes & fees
Aug 28 - Aug 29
Baymont by Wyndham Easley/Greenville

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
8.2 out of 10, Very Good, (1007)
"Great place to stay!"
The price is NT$2,595
NT$2,880 total
includes taxes & fees
Sep 12 - Sep 13
Microtel Inn & Suites by Wyndham Anderson/Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Downtown

2 out of top 10 points of interest in this area

While visiting Downtown, you might make a stop by sights like Seneca Historic District and Oconee County Library Seneca Branch.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Keowee Reservoir.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Keowee Reservoir, some noteworthy sights in the nearby area.

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Best guest reviews of Seneca

Top Seneca Hotel Reviews

Frequently asked questions

Where is the best place for a stay in Seneca?

Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.

If I need to cancel my hotel reservation in Seneca, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.

Where can I learn more about changing or cancelling my trip to Seneca?

To find more details about updating your trip to Seneca or cancelling it, click here.

What's the best budget-friendly accommodation in Seneca?

Based on reviews, Quality Inn Seneca US-123 is a popular 2.5-star hotel for our travelers looking for an economical choice, and features free breakfast and free WiFi. View all budget hotels in Seneca.

What's the best place to stay for a family vacation to Seneca?

Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.

What's the best LGBTQ-friendly place to stay in Seneca?

Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.

What's the best pet-friendly accommodation in Seneca?

Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.

What are some hotels with pools in Seneca?

Lakeside Lodge Clemson: Hotel, 7-minute walk from Lake Hartwell. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Fairfield Inn & Suites Seneca Clemson Univ Area and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.

What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?

Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.

What is staying in Seneca like?

Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 287 hotels and other accommodations to choose from. Find out more about Seneca.

What should I do while I'm visiting Seneca?

Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.

What's the weather like in Seneca?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.