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Our top choices for Santo Spirito hotels

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"This boutique was an absolute must stay. From the location to the comfort of our room and the lovely staff, it was all you could ask for during a stay in Florence. The walkability was incredible, and even though there is a lively crowd nightly outside of the building, your room is peaceful. Highly recommend this hotel to anyone looking for a unique stay in Florence! "
United States
Chris
The price is NT$5,072
NT$6,028 total
includes taxes & fees
Jan 29 - Jan 30
SPIRIT OF FLORENCE Boutique Rooms

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (172 reviews)
"The room was beautiful and clean, the staff was pleasant, breakfast was fantastic, 10/10"
United States
Dan
The price is NT$2,970
NT$3,715 total
includes taxes & fees
Jan 28 - Jan 29
La Fonderia Firenze

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (103 reviews)
"It was a great stay. The renovation style is very tasteful. "
Singapore
Maoying
The price is NT$4,909
NT$5,923 total
includes taxes & fees
Jan 31 - Feb 1
Oltrarno Splendid

Hotel Palazzo Guadagni

Hotel Palazzo Guadagni
3.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (201 reviews)
"Absolutely amazing stay! Great location to all major attractions, great restaurants nearby, beautiful rooms, certain room has Duomo view, incredibly helpful staff! Definitely recommend it and we are planning to come back! "
United States
Ann
The price is NT$6,721
NT$7,841 total
includes taxes & fees
Jan 27 - Jan 28
Hotel Palazzo Guadagni

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (169 reviews)
"Great location and extremely charming!"
United States
Brook
The price is NT$6,106
NT$7,240 total
includes taxes & fees
Feb 22 - Feb 23
Ottantotto Firenze

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (222 reviews)
"Loved my stay at this Hotel. Everything about it was wonderful. The staff was warm and welcoming, the location was in what is now the more interesting and authentic part of Florence. The Terrace overlooking the Gardens where you can eat breakfast was dazzling. In this age of ultra modern hotels, this one stood out because of its preservation of history and yet the room and the bathroom were large and roomy yet warm and cozy. "
United States
monica
The price is NT$5,775
NT$6,875 total
includes taxes & fees
Feb 1 - Feb 2
AdAstra Suites

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (233 reviews)
"The Torre del Cestello had the "Room with a View" (complete with garden below) that I had been dreaming of for my first visit to Florence. The desk staff were all pleasant, helpful, and set me up with a map and suggestions when I checked in. There was easy access in and out of the room. Quiet but incredibly convenient location. "
United States
Tanya
La Torre Del Cestello

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (613 reviews)
"Lovely clean, quiet and safe hotel. really good breakfast and staff. Good location within walking distance to everything. "
United Kingdom
Shaunna
The price is NT$3,931
NT$4,847 total
includes taxes & fees
Feb 5 - Feb 6
Hotel Horto Convento

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
8.8 out of 10, Excellent, (139 reviews)
"Our stay was wonderful! Roxy was so welcoming and helpful! The room and view was beautiful as well! Great location with amazing food and sights nearby! "
United States
Jacqueline
Residenza D'Epoca Al Numero 8

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (196 reviews)
"The room was clean a d comfortable, and the staff was very courteous and helpful. The location was also good with most attractions being a 30 to 40 minute walk or less."
United States
Roger
Foresteria Valdese di Firenze - Casa per Ferie

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.4 out of 10, Exceptional, (46 reviews)
"Excellent place to stay!"
United States
Diane
The price is NT$3,287
NT$4,064 total
includes taxes & fees
Feb 18 - Feb 19
Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,080 reviews)
"Everything great. A+ Looking forward to stay again. "
United States
Rafael
Palazzo Mannaioni Suites

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (178 reviews)
"Our stay here was wonderful! The host was so pleasant and the view from the terrace was beautiful. The location was in a great spot for enjoying the Florentine neighborhoods, and close to many of the restaurants recommended to us. We would stay here again in a heartbeat."
United States
Bianca
1900 Artevita

Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (189 reviews)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is NT$1,928
NT$2,457 total
includes taxes & fees
Feb 24 - Feb 25
Hotel Firenze 2000

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is NT$12,012
NT$13,736 total
includes taxes & fees
Jan 27 - Jan 28
Torre di Bellosguardo

Santo Spirito Venti

Santo Spirito Venti
Santo Spirito
8.8 out of 10, Excellent, (59 reviews)
"Great location, friendly staff, I definitely recommend it."
Canada
Pedro
Santo Spirito Venti

Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (342 reviews)
"Really a nice place, like the room style and good for family stay!"
United States
Ning
Casa Santo Nome di Gesù

Soggiorno Alessandra

Soggiorno Alessandra
Santo Spirito
8.6 out of 10, Excellent, (86 reviews)
"Alessandra is an amazing host, we had a perfect stay! The apartment is in excellent condition and very clean! "
United States
Elias
Soggiorno Alessandra

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (137 reviews)
"Ver clean and quiet, wonderful stay."
United States
kevin
The price is NT$2,108
NT$2,767 total
includes taxes & fees
Jan 27 - Jan 28
Drom Florence Rooms & Apartments

Santo Spirito View by Mmega

Santo Spirito View by Mmega
Santo Spirito
8.6 out of 10, Excellent, (7 reviews)
"All as advertised and recommend"
United States
Jeff
The price is NT$2,848
NT$6,942 total
includes taxes & fees
Jan 27 - Jan 28
Santo Spirito View by Mmega
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favorite options in the area include AdAstra Suites and Drom Florence Rooms & Apartments.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 472 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. A few places to visit in the area around Santo Spirito include Piazza di Santa Maria Novella, Piazza del Carmine, and Santa Maria della Carmine. When you're sightseeing in Florence, Brancacci Chapel and Il Nabucco di Matteo Gabellini are also worth a stop.