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Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

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Duomo

Uffizi Gallery and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

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San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Piazza della Repubblica are top sights worth seeing.

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Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

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Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

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Top Santo Spirito Hotel Reviews

Ottantotto Firenze

10/10 Excellent

"The hotel was very nice beautiful garden for breakfast, or having a drink. We would have enjoyed it more if we got a room on a higher floor. Try to ask in your reservation for high floor. We were on the main floor and the window to the street."

Hotel Horto Convento

10/10 Excellent

"This review is for the Della Calza, the sister hotel of Horto, where we were offered a n opportunity to stay. The Horto, which we originally booked, and arrived at, looked very nice., however upon arrival, the receptionist, Cherish, offered us an upgrade to the newly renovated Della Calza. Della Calza had an excellent spa, where guests could enjoy complimentary 2 hour services daily. Our room was beautifully clean, well appointed, facing the courtyard. The breakfast, which was included in our package, was fantastic. Close to Boboli Gardens, to the Roman Gate, walking distance to the Ponte Vecchio. Located in a beautiful neighborhood, surrounded by trattorias, shops, artisan workshops. The staff was very friendly and knowledgeable, helpful with dinner reservations, getting tips on transportation, and nearby attractions. Laura (receptionist) and her companions were very helpful, recommended a nice day trip to Fiesole, a beautiful nearby town. She was always there with a smile, ready to answer any questions. The breakfast staff (Mena and Elenora) were superb, welcoming offering the best morning cappuccino to complement the delicious breakfast. Khan, the bartender, stood out as a friendly, polite young man that could whip up a nice old fashioned, a terrific negroni, and of course, the best aperol spritz around. We look forward to returning to the beautiful Della Calza. I’m glad we chose a courtyard facing room, as the traffic on the street can get quite busy. Highly recommend."

Palazzo Mannaioni Suites

10/10 Excellent

"This is in the middle of the historic district of Florence. So convenient and a large apartment! The surprise for us was the deck/balcony with the view of the church. The staff were so welcoming and helpful. This is not a place to have a car, although they do provide suggestions for where to park if you need it."

Appartamenti degli Artisti by Mmega

10/10 Excellent

"Great apartment with high ceilings and modern amenities. Quiet street with good local restaurants nearby. One detail that could be improved is the floor in the shower was not sloped correctly for proper drainage flow. Not a major issue but could/should be resolved in the future. Would definitely stay there again."

Frequently asked questions

What is Santo Spirito like?

Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.

What's the best accommodation in Santo Spirito?

Based on our traveler data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 13-minute walk from Pitti Palace, and it offers free breakfast and a bar. Other good options for your stay in the neighborhood include Palazzo Mannaioni Suites and La Torre Del Cestello.

How many hotels can I expect to find in the Santo Spirito area?

Expedia has 501 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.

If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.

Where can I learn more about changing or cancelling my trip to Santo Spirito?

To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.

What can I see and do in this Florence neighborhood?

Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. A few places to visit in the area around Santo Spirito include Uffizi Gallery, Piazza del Carmine, and Santa Maria della Carmine. When you're sightseeing in Florence, Brancacci Chapel and Il Nabucco di Matteo Gabellini are also worth a stop.

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Our top choices for Santo Spirito hotels

Torre di Bellosguardo

Hotel Horto Convento

Oltrarno Splendid

Mamo Florence - Ardiglione Apartment

Palazzo Mannaioni Suites

SPIRIT OF FLORENCE Boutique Rooms

Da mamma Grazia in Oltrarno by MMega

AdAstra Suites

Hotel Firenze 2000

La Fonderia Firenze

La Torre Del Cestello

Lotus San Frediano by MMega

Ottantotto Firenze

Mamo Florence - Brancacci Apartment

Foresteria Valdese di Firenze - Casa per Ferie

Hotel Palazzo Guadagni

Oltrarno Classic by MMega

Residenza D'Epoca Al Numero 8

Mamo Florence - Boheme Apartment

Le Volte by Mmega

Where to stay in Santo Spirito

Historic Centre of Florence

Duomo

San Giovanni

Santa Maria Novella

Santa Croce

Top Santo Spirito Hotel Reviews

Ottantotto Firenze

Frequently asked questions

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