Find hotels in Santo Spirito, Florence from NT$3,192
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Discover 474 Santo Spirito hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Firenze 2000

Foresteria Valdese di Firenze - Casa per Ferie

Hotel Horto Convento

Casa Santo Nome di Gesù

Palazzo Mannaioni Suites

Palazzo D'Oltrarno - Residenza D'Epoca
Where to stay in Santo Spirito

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo
Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Santa Croce
Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.