Find hotels in Santo Spirito, Florence from NT$2,746

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Dec 11 - Dec 12
Tomorrow
Dec 12 - Dec 13
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

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Our top choices for Santo Spirito hotels

Lobby
Hotel Horto Convento

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (595)
"Excellent staff, so friendly and helpful. Lovely hotel in a great location. "
United Kingdom
Emma
The price is NT$3,683
NT$4,558 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Horto Convento
Lobby
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (339)
"I always enjoy my stay here. Nicely located, pleasant breakfast, terrific courtyard, nicely priced. "
United States
Marcie
Casa Santo Nome di Gesù
Interior
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (192)
"The staff was very helpful and room was clean "
United States
Cinda
Foresteria Valdese di Firenze - Casa per Ferie
Interior detail
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1071)
"Perfect stay"
United States
Juan P
Palazzo Mannaioni Suites
Front of property
Hotel Firenze 2000

Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (189)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is NT$2,200
NT$2,746 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Firenze 2000
Royal Double Room | Minibar, in-room safe, soundproofing, free WiFi
Oltrarno Splendid

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (97)
"It was Wonderful!!!"
United States
MARGARITA
The price is NT$5,270
NT$6,305 total
includes taxes & fees
Dec 15 - Dec 16
Oltrarno Splendid
Classic Suite, 1 King Bed | Premium bedding, down comforters, in-room safe, desk
La Torre Del Cestello

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (228)
"Great location and great rooms"
United States
David
The price is NT$2,303
NT$3,041 total
includes taxes & fees
Dec 14 - Dec 15
La Torre Del Cestello
Free daily buffet breakfast
La Fonderia Firenze

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (172)
"Breakfast outside was lovely"
United States
Kenneth
The price is NT$3,067
NT$3,809 total
includes taxes & fees
Dec 15 - Dec 16
La Fonderia Firenze
Front of property
Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.4 out of 10, Exceptional, (46)
"Excellent place to stay!"
United States
Diane
The price is NT$3,570
NT$4,362 total
includes taxes & fees
Dec 17 - Dec 18
Palazzo D'Oltrarno - Residenza D'Epoca
Comfort Double Room, Private Bathroom, Courtyard View | Courtyard view
Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (136)
"Ver clean and quiet, wonderful stay."
United States
kevin
Drom Florence Rooms & Apartments
Premium Double Room, Annex Building (in the garden) | Down comforters, in-room safe, individually decorated, desk
AdAstra Suites

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (221)
"Great Room - Lovely breakfast excellent strong Cappuccino and lovely yoghurts. Thanks see you soon. "
United Kingdom
Tim
The price is NT$6,200
NT$7,328 total
includes taxes & fees
Dec 16 - Dec 17
AdAstra Suites
Seasonal outdoor pool
Torre di Bellosguardo

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103)
"Beautiful property and wonderful staff."
United States
Brad
The price is NT$11,662
NT$13,336 total
includes taxes & fees
Dec 13 - Dec 14
Torre di Bellosguardo
Lounge
Hotel Palazzo Guadagni

Hotel Palazzo Guadagni

Hotel Palazzo Guadagni
3.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (200)
"Hotel Palazzo was stunning. I would definitely stay here again and I already can't wait to! The staff were so friendly and made you feel right at home. Everything was walking distance and the area was incredible!"
United States
Annyelis
The price is NT$5,831
NT$6,849 total
includes taxes & fees
Dec 15 - Dec 16
Hotel Palazzo Guadagni
Exterior detail
Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
8.8 out of 10, Excellent, (139)
"Our stay was wonderful! Roxy was so welcoming and helpful! The room and view was beautiful as well! Great location with amazing food and sights nearby! "
United States
Jacqueline
The price is NT$2,303
NT$3,041 total
includes taxes & fees
Dec 14 - Dec 15
Residenza D'Epoca Al Numero 8
Garden
Ottantotto Firenze

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (169)
"Fabulous hotel , breakfast was amazing , great location "
United Kingdom
SAMANTHA
The price is NT$5,744
NT$6,826 total
includes taxes & fees
Jan 7 - 2026/1/8
Ottantotto Firenze
Comfort Double Room | In-room safe, desk, free WiFi
L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
9.0 out of 10, Wonderful, (19)
"Clean and comfy room | Easy transportation | Safe"
United States
Gabriel
The price is NT$2,121
NT$2,768 total
includes taxes & fees
Dec 14 - Dec 15
L'Antica Porta Boutique B&B
Reception
Hostel Santa Monaca

Hostel Santa Monaca

Hostel Santa Monaca
Santo Spirito
8.0 out of 10, Very Good, (60)
"I found it easy to move around and walked everywhere. Staff super friendly. Ten people in one room was a bit much, but overall comfortable. Thank you.!"
Canada
Alma
Hostel Santa Monaca
Reception
Home in Florence

Home in Florence

Home in Florence
Santo Spirito
9.0 out of 10, Wonderful, (70)
"Perfect place, super friendly owners, really helpful. "
United Kingdom
Paul
The price is NT$2,492
NT$3,176 total
includes taxes & fees
Dec 12 - Dec 13
Home in Florence
Front of property
Soderini Apartments by MMega

Soderini Apartments by MMega

Soderini Apartments by MMega
Santo Spirito
8.8 out of 10, Excellent, (9)
"Having laundry in the room was great! The location was nice. Easy to walk to tourist sites. Grocery store was almost next door. Gelato store was almost next door. All the bases were covered!"
Canada
Brett
The price is NT$2,419
NT$5,997 total
includes taxes & fees
Dec 12 - Dec 13
Soderini Apartments by MMega
22-inch flat-screen TV with digital channels, TV
1900 Artevita

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (176)
"This property is great and the manager is very kind and helpful."
United States
Elizabeth
1900 Artevita
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

Via de' Calzaiuoli and Giotto's Campanile are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Piazza Santa Croce showing a city and street scenes

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Hotel Horto Convento

Hotel Horto Convento

10/10 Excellent
"Room was great, staff excellent, Cherish did outstanding job, location excellent "
randi 5-night trip
Posted 5 days ago
Hotel Horto Convento

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Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favorite options in the area include AdAstra Suites and SPIRIT OF FLORENCE Boutique Rooms.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 474 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. A few places to visit in the area around Santo Spirito include Piazza del Carmine, Santa Maria della Carmine, and Brancacci Chapel. When you're sightseeing in Florence, Il Nabucco di Matteo Gabellini and Teatro Comunale Florence are also worth a stop.