Find hotels in Santa Ana, Antigua Guatemala

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Our top choices for Santa Ana hotels

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (50 reviews)
"Great place !!"
United States
Abner Israel Polanco
The price is NT$2,064
NT$2,518 total
includes taxes & fees
Feb 17 - Feb 18
Casa Buho B&B

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (22 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is NT$1,497
NT$1,826 total
includes taxes & fees
Mar 2 - Mar 3
Hostal Casa Buho

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.8 out of 10, Excellent, (13 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
Villas Santa Ana-Ricardo

Hotel y Restaurante Vista Verde

Hotel y Restaurante Vista Verde
3.0 star property
5.9 km from Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"Great room (#3) with high quality mattress, nice towels and pretty bathroom, lacks some toiletries, quiete place with awesome graden views, property rune by their owners, highly recommended! "
United States
Sergio
The price is NT$2,106
NT$2,570 total
includes taxes & fees
Feb 17 - Feb 18
Hotel y Restaurante Vista Verde

Pensativo House Hotel

Pensativo House Hotel
4.5 star property
1 km from Santa Ana
9.4 out of 10, Exceptional, (399 reviews)
"Rooms were clean and bed and pillows were comfortable with good A/C. Staff was very helpful and were always ready to assist. Food was excellent. "
United States
Carlos Alvarez
Pensativo House Hotel

Hotel Posada del Angel

Hotel Posada del Angel
4.0 star property
1 km from Santa Ana
9.6 out of 10, Exceptional, (285 reviews)
"We had a great stay! The hotel is a very charming boutique hotel nestled in Antigua. The room was very comfortable and we were able to rest very well. The staff was always very helpful and friendly. "
United States
Janelle
Hotel Posada del Angel

EL TEJAR HOSTAL

EL TEJAR HOSTAL
3.0 star property
21 km from Santa Ana
8.2 out of 10, Very Good, (18 reviews)
"Staff very friendly and helpful. Room clean and quiet. "
United States
ILEANA
The price is NT$1,256
NT$1,532 total
includes taxes & fees
Feb 20 - Feb 21
EL TEJAR HOSTAL

Meson Panza Verde

Meson Panza Verde
3.5 star property
1.1 km from Santa Ana
9.2 out of 10, Wonderful, (447 reviews)
"This was the most amazing hotel we stayed in Antigua! Absolutely beautiful and comfortable! Staff was always very friendly and helpful. Restaurant had amazing atmosphere and food. Will definitely be returning! "
United States
Janelle
The price is NT$4,782
NT$5,834 total
includes taxes & fees
Mar 8 - Mar 9
Meson Panza Verde

Las Cruces Boutique Hotel

Las Cruces Boutique Hotel
4.0 star property
Historic Center, 1.4 km from Santa Ana
9.8 out of 10, Exceptional, (231 reviews)
"Lovely place with exceptional service "
United States
Juan Carlos
The price is NT$7,860
NT$9,589 total
includes taxes & fees
Feb 18 - Feb 19
Las Cruces Boutique Hotel

Dai Nonni Hotel

Dai Nonni Hotel
3.0 star property
22.4 km from Santa Ana
9.2 out of 10, Wonderful, (348 reviews)
"Hotel is clean quiet and the staff was awesome I recommend this place breakfast was also really good "
United States
Juan
The price is NT$1,918
NT$2,340 total
includes taxes & fees
Feb 22 - Feb 23
Dai Nonni Hotel

Hotel Las Farolas

Hotel Las Farolas
3.5 star property
1.2 km from Santa Ana
9.2 out of 10, Wonderful, (721 reviews)
"It is relatively close and walkable to the central plaza and all amenities around it."
United States
helmuth
The price is NT$7,074
NT$8,630 total
includes taxes & fees
Mar 14 - Mar 15
Hotel Las Farolas

Hotel Las Marías

Hotel Las Marías
3.0 star property
1.9 km from Santa Ana
9.2 out of 10, Wonderful, (435 reviews)
"clean room in a good area"
United States
roghayeh
The price is NT$2,993
NT$3,651 total
includes taxes & fees
Feb 22 - Feb 23
Hotel Las Marías

Ciel-Luxe Hotels

Ciel-Luxe Hotels
3.5 star property
Historic Center, 1.4 km from Santa Ana
8.6 out of 10, Excellent, (375 reviews)
"Friendly and accomadating staff"
United States
Kaushal
Ciel-Luxe Hotels

Suites Terraza Imperial

Suites Terraza Imperial
3.0 star property
22.5 km from Santa Ana
9.0 out of 10, Wonderful, (305 reviews)
"Nice clean space with fictional kitchenette."
United States
Rochelle
Suites Terraza Imperial

San Rafael Hotel

San Rafael Hotel
4.0 star property
Historic Center, 1.5 km from Santa Ana
9.8 out of 10, Exceptional, (448 reviews)
"Great room"
United States
Steven
The price is NT$6,602
NT$8,149 total
includes taxes & fees
Feb 24 - Feb 25
San Rafael Hotel

Hotel Genessis

Hotel Genessis
3.5 star property
0.9 km from Santa Ana
9.2 out of 10, Wonderful, (110 reviews)
"Gorgeous gorgeous hotel! Staff was so friendly! Will definitely stay here again!"
United States
Sandy
Hotel Genessis

Hotel Cacique Real

Hotel Cacique Real
3.0 star property
1.8 km from Santa Ana
8.8 out of 10, Excellent, (170 reviews)
"A beautiful hotel that’s in a nice location that isn’t far from all the main tourist attractions but is also slightly calmer than the main high streets. The staff were all really helpful and friendly and the breakfast was great."
United Kingdom
Magdalene
Hotel Cacique Real

Aurora Express

Aurora Express
3.5 star property
20.7 km from Santa Ana
9.0 out of 10, Wonderful, (623 reviews)
"I have stayed here many times. It is a beautiful property. "
United States
Scott
The price is NT$1,669
NT$2,037 total
includes taxes & fees
Mar 17 - Mar 18
Aurora Express

Naif Boutique Hotel

Naif Boutique Hotel
3.0 star property
Historic Center, 1.4 km from Santa Ana
9.0 out of 10, Wonderful, (398 reviews)
"We had a great stay! Very comfortable and nice."
United States
Janelle
Naif Boutique Hotel

Casa Santa Rosa Hotel Boutique

Casa Santa Rosa Hotel Boutique
3.5 star property
Historic Center, 1.4 km from Santa Ana
9.6 out of 10, Exceptional, (340 reviews)
"Best place to stay in Antigua!!"
United States
Maria
The price is NT$4,559
NT$5,562 total
includes taxes & fees
Feb 23 - Feb 24
Casa Santa Rosa Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favorite hotel to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking. Another top choice in the area is Hostal Casa Buho.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 16 hotels and other accommodations in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about updating your trip to Santa Ana or cancelling it, click here.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.