Find hotels in Sanibel Isles, Sanibel

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sanibel Isles hotels

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 2.3 km from Sanibel Isles
9.8 out of 10, Exceptional, (9 reviews)
"The property was beautiful, everything was in perfect condition, would definitely go back!!"
United States
Jennifer
The price is NT$11,834
NT$13,676 total
includes taxes & fees
Apr 14 - Apr 15
The Anchor Inn

The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
10.3 km from Sanibel Isles
7.6 out of 10, Good, (377 reviews)
"Great and clean hotel friendly and family oriented! "
United States
Noel
The price is NT$5,527
NT$7,591 total
includes taxes & fees
Apr 5 - Apr 6
The Bay Inn at Lani Kai

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
19.4 km from Sanibel Isles
9.6 out of 10, Exceptional, (241 reviews)
"Beautiful resort, great communication, super clean "
United States
Ronald
The price is NT$2,723
NT$5,180 total
includes taxes & fees
Apr 13 - Apr 14
Matlacha on Shoreview

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
10.1 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,003 reviews)
"Suite was clean… staff very friendly….food outstanding! We had a great week!"
United States
Shawn William
The price is NT$7,635
NT$9,794 total
includes taxes & fees
Apr 5 - Apr 6
The Westin Cape Coral Resort At Marina Village

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
25.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (771 reviews)
"Clean property. Amazingly friendly front desk staff at all times. Would definitely stay again."
United States
Gretchen
The price is NT$4,194
NT$4,677 total
includes taxes & fees
Apr 5 - Apr 6
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
15.3 km from Sanibel Isles
8.8 out of 10, Excellent, (1,247 reviews)
"good location"
United States
dan
The price is NT$3,204
NT$3,573 total
includes taxes & fees
Apr 1 - Apr 2
Dolphin Key Resort

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
14.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1,002 reviews)
"Room was clean and staff was fantastic "
United States
Wayne
The price is NT$3,652
NT$4,072 total
includes taxes & fees
Apr 5 - Apr 6
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
15.5 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,309 reviews)
"Great location, clean rooms, wonderful basic breakfast and coffee, I will be back again."
United States
Eduardo
The price is NT$3,234
NT$3,606 total
includes taxes & fees
Apr 13 - Apr 14
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Park Motel

Park Motel
2.5 star property
30.1 km from Sanibel Isles
9.4 out of 10, Exceptional, (40 reviews)
"Clean, quiet, very friendly and helpful staff, hot tub in room very relaxing."
United States
Kristeen
The price is NT$3,028
NT$3,376 total
includes taxes & fees
Apr 1 - Apr 2
Park Motel

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
17.5 km from Sanibel Isles
5.8 out of 10, (1,008 reviews)
"It was perfect for my one night stay definitely will be coming back "
United States
Marice
The price is NT$3,592
NT$4,373 total
includes taxes & fees
Mar 18 - Mar 19
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
5.1 km from Sanibel Isles
9.6 out of 10, Exceptional, (154 reviews)
"Nice new rooms and great outdoor seating on the waterway, we saw lots of manatees "
United States
Ellen
The price is NT$5,070
NT$6,725 total
includes taxes & fees
Apr 1 - Apr 2
Off the Charts Inn & Out Island Resort

SpringHill Suites by Marriott Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero
2.5 star property
27.3 km from Sanibel Isles
9.2 out of 10, Wonderful, (854 reviews)
"Clean room, friendly staff breakfast is good"
United States
Maribel
The price is NT$5,144
NT$5,896 total
includes taxes & fees
Apr 6 - Apr 7
SpringHill Suites by Marriott Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero
3.5 star property
27.4 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,142 reviews)
"Great pool, pool area and hot tub, room was very clean, staff are great"
United States
Daniel
The price is NT$4,834
NT$5,390 total
includes taxes & fees
Apr 1 - Apr 2
Embassy Suites by Hilton Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero
3.5 star property
25.8 km from Sanibel Isles
9.4 out of 10, Exceptional, (496 reviews)
"Room was clean and had what we needed during our stay."
United States
James
The price is NT$4,585
NT$5,112 total
includes taxes & fees
Apr 12 - Apr 13
TownePlace Suites by Marriott Fort Myers Estero

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
3.5 star property
27 km from Sanibel Isles
8.6 out of 10, Excellent, (858 reviews)
"Great location and friendly staff."
United States
Matthew
The price is NT$6,279
NT$7,002 total
includes taxes & fees
Apr 5 - Apr 6
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

Drury Inn & Suites Fort Myers Airport FGCU

Drury Inn & Suites Fort Myers Airport FGCU
3.0 star property
26.4 km from Sanibel Isles
9.8 out of 10, Exceptional, (1,002 reviews)
"Always a great stay"
United States
David
The price is NT$3,748
NT$4,180 total
includes taxes & fees
Apr 5 - Apr 6
Drury Inn & Suites Fort Myers Airport FGCU

Hampton Inn & Suites Fort Myers-Estero/FGCU

Hampton Inn & Suites Fort Myers-Estero/FGCU
2.5 star property
27.5 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,004 reviews)
"The staff wasvery friendly and the roo.s were great! We enjoyed the awesome breakfast."
United States
Cheryl
The price is NT$4,703
NT$5,244 total
includes taxes & fees
Apr 5 - Apr 6
Hampton Inn & Suites Fort Myers-Estero/FGCU

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,681 reviews)
"Super nice pool and bar area and easy to get to the beach. Clean rooms and great location. "
United States
Marjorie
The price is NT$11,815
NT$13,974 total
includes taxes & fees
Apr 14 - Apr 15
Sanibel Island Beach Resort

TownePlace Suites by Marriott Fort Myers Gulf Coast

TownePlace Suites by Marriott Fort Myers Gulf Coast
3.0 star property
25.8 km from Sanibel Isles
9.2 out of 10, Wonderful, (164 reviews)
"Great size room and the front desk staff was Great!"
United States
Karen
The price is NT$5,443
NT$6,069 total
includes taxes & fees
Mar 29 - Mar 30
TownePlace Suites by Marriott Fort Myers Gulf Coast

Tarpon Tale Inn

Tarpon Tale Inn
3.0 star property
East End, 3.4 km from Sanibel Isles
9.6 out of 10, Exceptional, (401 reviews)
"Our room was clean and comfortable and the staff was friendly and helpful. We loved our visit to Sanibel and staying at the Tarpon Tale Inn and look forward to going there again some day."
United States
Ed
The price is NT$9,573
NT$10,674 total
includes taxes & fees
Mar 23 - Mar 24
Tarpon Tale Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas and neighborhoods for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Sanctuary

While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach.

Top Sanibel Isles Hotel Reviews

Frequently asked questions

What's it like in Sanibel Isles?
Travelers to the Sanibel Isles neighborhood in Sanibel will be sure to enjoy their stay.
How many hotels will I find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 7 hotels and other accommodations in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best deals available in Sanibel Isles.
Where can I learn more about changing or cancelling my trip to Sanibel Isles?
To access more information about picking new dates or cancelling your trip to Sanibel Isles, go to https://www.expedia.com/service/.
What is there to do in this Sanibel neighborhood?
Woodring Point, Woodring Beach, and Dunes Golf and Tennis Club are just a few of the places to visit in and around Sanibel Isles. Bailey's Beach and Periwinkle Way are also worth a visit when you're out sightseeing in Sanibel.

Explore a world of travel with Expedia