Downtown South San Francisco, CA

San Francisco

Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA
Aerial view of the South San Francisco area
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Popular places to visit


Downtown South San Francisco Hotel Deals

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is NT$3,643 per night from Apr 11 to Apr 12
NT$3,643
NT$4,269 total
Apr 11 - Apr 12
includes taxes & fees
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast ...
8.2/10 Very Good! (1,978 reviews)
The stay was very pleasant the staff helpful and pleasant. No issues at all will stay again

Reviewed on 2026/4/2

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is NT$4,214 per night from Apr 12 to Apr 13
NT$4,214
NT$4,960 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (5,491 reviews)
Everything was good clean, i loved

Reviewed on 2026/4/3

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is NT$5,092 per night from Apr 4 to Apr 5
NT$5,092
NT$5,994 total
Apr 4 - Apr 5
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (2,947 reviews)
This hotel is in an excellent location. It serves its purpose. It’s older but the room was clean and it was quiet.

Reviewed on 2026/4/3

Handlery Union Square Hotel
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is NT$4,447 per night from Apr 12 to Apr 13
NT$4,447
NT$6,551 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,372 reviews)
Great location. Full breakfast with efficient service. Bathrooms a little small and could use some updates.

Reviewed on 2026/4/3

Hotel Riu Plaza Fisherman's Wharf
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
The price is NT$2,571 per night from Apr 7 to Apr 8
NT$2,571
NT$3,591 total
Apr 7 - Apr 8
includes taxes & fees
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
YOTEL San Francisco
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
The price is NT$6,046 per night from Apr 10 to Apr 11
NT$6,046
NT$7,116 total
Apr 10 - Apr 11
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
8.4/10 Very Good! (1,230 reviews)
Very clean room and bathroom!:) lovely staff

Reviewed on 2026/4/3

Hilton San Francisco Union Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Downtown South San Francisco

Aerial View Of Urban Neighborhood

Noe Valley

5/5(1 area review)

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
Mission District

Mission District

3.5/5(141 area reviews)

Mission District is a destination travelers like for its bars, and you might hop aboard the metro at 16th Street Mission Station or 24th Street Mission Station to explore sights like SOMA Pilipinas.

Mission District
Potrero Hill

Potrero Hill

The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Museum of Craft & Design are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area.

Potrero Hill
Sunset District

Sunset District

3.5/5(176 area reviews)

Travelers choose Sunset District for its pristine beaches. Hop aboard the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop and check out top sights like Ocean Beach.

Sunset District
Outer Sunset

Outer Sunset

When in Outer Sunset and the surrounding area, you'll want to check out sights like Ocean Beach or Blue Heron Lake and hop on the metro to see more the city at Judah St & 34th Ave Stop or Judah Street & Sunset Boulevard Station.

Outer Sunset
South of Market

South of Market

3.5/5(3,694 area reviews)

Oracle Park and San Francisco Bay are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

South of Market


Downtown South San Francisco, CA