Find Business Hotels in San Diego, CA

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on San Diego Business Hotels

Tonight
Dec 21 - Dec 22
Tomorrow
Dec 22 - Dec 23
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Our top choices for San Diego business-friendly hotels

Suite, 1 King Bed with Sofa Bed (Marina Tower Newly Renovated Marina view) | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very Good, (3175)
"Great stay! "
United States
Melissa
The price is NT$3,353
NT$4,991 total
includes taxes & fees
Dec 25 - Dec 26
Sheraton San Diego Resort
Reception
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld
3.0 star property
Point Loma
9.2 out of 10, Wonderful, (431)
"Clean rooms, friendly staff."
United States
KARLA
The price is NT$3,193
NT$3,670 total
includes taxes & fees
Jan 4 - 2026/1/5
Hampton Inn & Suites by Hilton San Diego SeaWorld
Courtyard
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley
8.4 out of 10, Very Good, (1904)
"Excellent location"
United States
Paolo
The price is NT$3,080
NT$3,509 total
includes taxes & fees
Jan 4 - 2026/1/5
DoubleTree by Hilton San Diego - Del Mar
Exterior
Best Western Seven Seas

Best Western Seven Seas

Best Western Seven Seas
3.0 star property
Mission Valley
8.0 out of 10, Very Good, (3057)
"Nice room, good ambiance, central location "
United States
ANDREW
The price is NT$2,339
NT$2,689 total
includes taxes & fees
Dec 22 - Dec 23
Best Western Seven Seas
Outdoor pool, sun loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1884)
"Enjoyed my stay"
United States
Brandon
The price is NT$3,734
NT$5,877 total
includes taxes & fees
Jan 4 - 2026/1/5
Hilton San Diego Bayfront
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3555)
"Very friendly staff "
United States
Robert
The price is NT$3,381
NT$3,725 total
includes taxes & fees
Jan 4 - 2026/1/5
Best Western Plus Marina Gateway Hotel
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6044)
"Always an amazing stay"
United States
Jana
The price is NT$4,266
NT$5,861 total
includes taxes & fees
Dec 24 - Dec 25
Wyndham San Diego Bayside
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillowtop beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (766)
"Friendly staff and clean rooms. "
Canada
Justine
The price is NT$3,461
NT$4,013 total
includes taxes & fees
Dec 22 - Dec 23
The DEXTRO Little Italy, BW Premier Collection
Lobby
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
Point Loma
7.4 out of 10, Good, (4112)
"Room was very clean and staff very pleasant "
Canada
Brian
The price is NT$2,809
NT$3,229 total
includes taxes & fees
Dec 22 - Dec 23
Wyndham Garden San Diego Near SeaWorld
Lobby
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach
9.0 out of 10, Wonderful, (807)
"good place to stay"
United States
Sisi
The price is NT$3,251
NT$3,737 total
includes taxes & fees
Dec 30 - Dec 31
Fairfield Inn & Suites by Marriott San Diego Pacific Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top San Diego Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"All excellent "
Gary Vincent 1-night trip
Posted 20 hours ago
Wyndham San Diego Bayside

Frequently asked questions

How much do business-friendly hotels in San Diego cost?
You can expect to pay between NT$2,689 and NT$5,877 per night for business-friendly hotels in San Diego. Awesome deals on properties that are suitable for corporate travelers are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in San Diego?
A lot of corporate travelers recommend TownePlace Suites by Marriott San Diego Airport/Liberty Station. This 3-stars stay offers amenities such as a barbecue grill and a swimming pool. Tower23 Hotel is another top-rated option. It has a 4-stars rating and conveniences including an ocean view and a Tempur-Pedic mattress. You can pick from multiple business-friendly hotels in San Diego that have a total average guest review rating of 8.4.
How many business-friendly hotels are there in San Diego?
San Diego offers 248 hotels that accommodate corporate travelers. Whether you're searching for a central location or conveniences like dependable WiFi and conference rooms, you'll find the right property on Expedia.
What are the best cheap business-friendly hotels in San Diego?
TownePlace Suites by Marriott San Diego Airport/Liberty Station is a great choice for corporate travelers after a money-saving option. It comes with amenities like a swimming pool and a barbecue grill. Another economical stay for a work-related trip is  Hampton Inn & Suites San Diego Airport Liberty Station. An electric car charging station and a swimming pool are two of the conveniences here. Rates for business-friendly hotels in San Diego start at only NT$2,689 per night, so you'll have cash left over to spend on post-meeting activities. However, your San Diego visit shouldn't be all work and no play. Check out a few fun and free attractions, such as Mission Bay and Mission Beach. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in San Diego?
Crown City Inn is a top pick, located about 3 kilometers southwest of downtown San Diego. Offering pool sun loungers and a garden, this business-friendly motel has what you need to get the job done. The Rambler Motel also caters to corporate travelers. It's around 10 kilometers southeast of central San Diego and includes a firepit, a swimming pool and more.There are so many things to do and see around San Diego. Take time out from your hectic schedule to visit leading attractions like San Diego Zoo and Mission Bay.
Are there any family-friendly hotels in San Diego that are also business friendly?
Pacific Terrace Hotel is a top pick for both leisure and corporate guests. A nearby theme park and a nearby beach are just two of the amenities you'll find at this 4-stars San Diego escape. Alternatively, get away with the family and get down to business at Homewood Suites by Hilton San Diego Airport/Liberty Station. Enjoy the use of conveniences such as complimentary breakfast and a playground at this leading 3-stars property. San Diego has plenty of family-friendly attractions to discover once you've wrapped up work. Make new memories with the kids at San Diego Zoo and Mission Bay.
Are there any 5-star business-friendly hotels in San Diego?
Book your spot at Pendry San Diego. Around 0.64 kilometers from the downtown area of San Diego, this business-friendly retreat has a 5-star rating and amenities including designer toiletries and room service. THE US GRANT, a Luxury Collection Hotel, San Diego is another 5-star pick that's ideal for corporate guests. It's situated about 0.16 kilometers from the city center and offers designer toiletries and concierge services.
Why book your business-friendly hotel in San Diego with Expedia?
Expedia is here to help you find an ideal business-friendly hotel when you need to travel for work. From conference spaces and meeting rooms to on-site cafés and more, our stays have the things you need to get the job done.
How can I find cheap business-friendly hotels in San Diego?
When work takes you on the road in San Diego, our "business friendly" filter will help you find the right hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to get the job done. Another handy tip? Narrow your search by your preferred star rating and budget to see the cheapest accommodations.
What is there to do in San Diego near my business-friendly hotel?
Whatever you love to do, San Diego has loads to keep you occupied. San Diego Zoo, Mission Bay and Mission Beach are on most visitors' sightseeing plans. Don't go home without exploring Coronado Beach, Seaport Village and Old Town San Diego State Park either. With Expedia's business-friendly hotel deals, you can discover even more wonderful attractions like these with the cash you save.

Explore a world of travel with Expedia