Medical Center District, TX
San Antonio
Visit Medical Center District
Popular places to visit
River Walk
4.5/5(7,401 reviews)
River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and shops in this walkable area.
Six Flags Fiesta Texas
4.5/5(981 reviews)
Enjoy the rides and games at Six Flags Fiesta Texas and see why this is a favorite theme park in San Antonio. Experience the lively festivals and acclaimed theater scene in this family-friendly area.
Lackland Air Force Base
4.5/5(1,271 reviews)
Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this family-friendly area.
Henry B. González Convention Center
4.5/5(757 reviews)
During your trip, find out what's happening at Henry B. González Convention Center, a top convention center in San Antonio. Experience the great live music and fascinating museums in this walkable area.
San Antonio SeaWorld
4.5/5(1,609 reviews)
Make time to visit the sea animals who live at San Antonio SeaWorld and find out why this is a popular attraction in San Antonio. Amble around this family-friendly area's seaside or experience its lively festivals.
Alamodome
4.5/5(939 reviews)
Catch an event at Alamodome during your trip to San Antonio. Experience the acclaimed theater scene and fascinating museums in this walkable area.
Medical Center District Hotel Deals
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is NT$2,801 per night from May 19 to May 20
NT$2,801
NT$3,311 total
May 19 - May 20
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,349 reviews)
"Hotel is in a convenient location but my biggest issues was that the TV did not always work, the front desk would send a guy up to the room but you should not have to call each time your TV does not work. I am used to the room having shampoo, conditioner, and body wash. You only had a 0.7ml of shampoo ..."
Reviewed on 2026/5/18
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is NT$3,379 per night from May 25 to May 26
NT$3,379
NT$4,015 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (1,062 reviews)
"While the staff was polite and attempted to accommodate us by transferring us to another room, the overall condition of both rooms did not meet the expectations of a deluxe room. The furniture showed visible wear and damage, including torn cushions, chipped finishes, and heavily worn carpet that ..."
Reviewed on 2026/5/18
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is NT$3,092 per night from Jun 1 to Jun 2
NT$3,092
NT$3,654 total
Jun 1 - Jun 2
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,004 reviews)
"When I checked for a week and payed CASH IN TOWN FOR A MILITARY EVENT AT LACKLAND AFB DRIVE 25 hours, NO ONE INFORMED ME IF I HAD TO LEAVE EARLY I NEED TO GIVE A NOTICE OR THE HOTEL WOULD RETAIN A FEE OF 129.00. It just not a way to handle playing customers of over 25 years!"
Reviewed on 2026/5/8
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is NT$4,290 per night from Jun 1 to Jun 2
NT$4,290
NT$5,071 total
Jun 1 - Jun 2
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,641 reviews)
"I couldn't give a high enough recommendation! The staff was great. Location great. Hotel just beautiful! Josh gave us some great tips for out stay! Drury Happy Hour and Dinner atmosphere led to meeting Travellers from everywhere and sparked great conversations. One block to a Riverwalk entrance!"
Reviewed on 2026/5/18
Menger Hotel
204 Alamo Plaza San Antonio TX
The price is NT$2,815 per night from May 20 to May 21
NT$2,815
NT$3,328 total
May 20 - May 21
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
8.8/10 Excellent! (4,009 reviews)
"We loved the history of the hotel and the location was perfect being next to the Alamo and to the riverwalk and to the shopping plaza. The room was spacious for our family of 3 and very clean . We enjoyed the pool and had a drink in the bar!"
Reviewed on 2026/5/18
Sonesta ES Suites San Antonio Downtown Alamo Plaza
425 Bonham San Antonio TX
The price is NT$3,191 per night from May 20 to May 21
NT$3,191
NT$3,772 total
May 20 - May 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,168 reviews)
"Room set up was spacious, cozy and homey. Loved it!"
Reviewed on 2026/5/18
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Other neighborhoods around Medical Center District
Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.
Shearer Hills - Ridgeview
If you're spending some time in Shearer Hills - Ridgeview, North Star Mall and San Pedro Driving Range & Par 3 Course are top sights worth seeing.
Midtown
3.5/5(201 area reviews)
Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Tobin Hill
Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like San Antonio Museum of Art and McFarlin Tennis Center.
Uptown
While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.
Medical Center District, TX
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- Visit Pipe Creek
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- Visit Bulverde
- Visit Fischer
- Visit Floresville
- Visit Downtown San Antonio
- Visit Canyon Lake
- Basilica of the National Shrine of the Little Flower
- Visit Kendalia
- Visit Leming
- Visit Schertz
- Visit McQueeney
- Visit Alamo Plaza
- Visit Converse
- Wonderland of the Americas Mall
- Visit Castroville
- Visit La Coste
- Visit Stone Oak
- Christus Santa Rosa Hospital - Medical Center
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