Medical Center District, TX

San Antonio

A cityscape with a prominent tower, a large body of water, and a sunset.
A canal with colorful umbrellas and trees along the banks.
A riverside café with colorful umbrellas and tables.
A tranquil waterway flanked by lush greenery and stone pathways.
A canal with a boat, surrounded by lush greenery and a stone bridge.

Stay near popular Medical Center District attractions


Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is NT$2,838 per night from Aug 23 to Aug 24
NT$2,838
NT$3,354 total
Aug 23 - Aug 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is NT$2,844 per night from Aug 28 to Aug 29
NT$2,844
NT$3,362 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
Courtyard by Marriott Medical Center San Antonio
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is NT$2,876 per night from Aug 26 to Aug 27
NT$2,876
NT$3,399 total
Aug 26 - Aug 27
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites San Antonio Northwest Medical Center
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is NT$3,440 per night from Sep 20 to Sep 21
NT$3,440
NT$4,088 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,151 reviews)
"Please don’t expect any help or flexibility from this Hotel. I notified them within 24 hours regarding my cancellation and they wouldn’t cooperate. Unlike any other hotel chain, they would want you to pay in advance. I visit the area a lot for business and I’ll never stay in that property."

Reviewed on 2026/8/19

San Antonio Marriott Northwest Medical Center
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3 out of 5
303 Blum Street San Antonio TX
The price is NT$2,272 per night from Sep 7 to Sep 8
NT$2,272
NT$3,320 total
Sep 7 - Sep 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the breakfast ...
8/10 Very Good! (4,091 reviews)
"Room was clean and hotel is well situated to the riverwalk. The breakfast was nice and the pool and hot tub were very much appreciated. My only real note is that there is no where to get water beside their little market where it is sold for 3.25 a bottle."

Reviewed on 2026/8/19

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is NT$4,090 per night from Sep 20 to Sep 21
NT$4,090
NT$4,835 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District

Downtown San Antonio

The stunning river views and popular shops are just a few highlights of Downtown San Antonio. Make a stop by Alamo or Alamodome while you're exploring the area.

Uptown

While visiting Uptown, you might make a stop by sights like Alamo Quarry Market and San Antonio Zoo and Aquarium.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Dub Farris Athletic Complex.



Medical Center District, TX

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