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Our top choices for Piazza Santo Spirito hotels

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
San Frediano, < 0.1 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"Easy check in and very helpful and polite "
United States
Remi
The price is NT$10,695
NT$12,203 total
includes taxes & fees
May 27 - May 28
SPIRIT OF FLORENCE Boutique Rooms

Bella Vista City View by MMega

Bella Vista City View by MMega
San Frediano, < 0.1 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (7 reviews)
"Fantastic apartment on the best, local square for casual dinners and drinks in the less touristic area."
Denmark
Michael Valentin
The price is NT$5,061
NT$9,667 total
includes taxes & fees
Jun 7 - Jun 8
Bella Vista City View by MMega

AdAstra Suites

AdAstra Suites
San Frediano, 0.2 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (228 reviews)
"Great breakfast! Helpful staff! Very private and quiet. "
United States
howard
The price is NT$13,813
NT$15,707 total
includes taxes & fees
Jun 15 - Jun 16
AdAstra Suites

Palazzo Martellini Residenza d'Epoca

Palazzo Martellini Residenza d'Epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (72 reviews)
"Very nice and so close to all places by walking."
United States
Mary
The price is NT$8,867
NT$10,193 total
includes taxes & fees
Jun 8 - Jun 9
Palazzo Martellini Residenza d'Epoca

Casa Botticelli

Casa Botticelli
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (47 reviews)
"Friendly staff and excellent breakfast "
United States
Mingjiang
The price is NT$11,617
NT$13,291 total
includes taxes & fees
Jun 1 - Jun 2
Casa Botticelli

B & Beatrice

B & Beatrice
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (111 reviews)
"Good location Helpful staff"
United States
maryjo
The price is NT$4,861
NT$5,786 total
includes taxes & fees
May 25 - May 26
B & Beatrice

Numa Florence Palazzo Belfiore

Numa Florence Palazzo Belfiore
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (388 reviews)
"Great location and also great price! Very spacious. Would recommend!"
United States
Elizabeth
The price is NT$12,615
NT$14,316 total
includes taxes & fees
May 31 - Jun 1
Numa Florence Palazzo Belfiore

Ponte Vecchio Suites & Spa

Ponte Vecchio Suites & Spa
4.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (1,002 reviews)
"Great Location, exceptional staff!"
United States
Frederico
The price is NT$10,429
NT$11,985 total
includes taxes & fees
Jun 2 - Jun 3
Ponte Vecchio Suites & Spa

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
San Frediano, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (149 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is NT$5,818
NT$6,840 total
includes taxes & fees
Jun 10 - Jun 11
Drom Florence Rooms & Apartments

Stella d'Italia

Stella d'Italia
4.0 star property
Duomo, 0.6 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (203 reviews)
"Stunning property, beautiful room with a super comfortable bed, staff on the property so friendly and helpful! Breakfast was delicious. "
United States
John
The price is NT$13,750
NT$15,638 total
includes taxes & fees
Jun 14 - Jun 15
Stella d'Italia

Canto degli Scali

Canto degli Scali
San Giovanni, 0.6 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (242 reviews)
"fantastic apartment stay, really didn't want to leave - excellent service and cleaning, friendly and very helpful. "
South Africa
Andrew
The price is NT$9,549
NT$10,943 total
includes taxes & fees
Jun 1 - Jun 2
Canto degli Scali

Portrait Firenze - Lungarno Collection

Portrait Firenze - Lungarno Collection
5.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (313 reviews)
"The rooms are beautiful and immaculately kept. The staff is so personable and thoughtful. The location is unmatched highly recommend this hotel!"
United States
Laura
The price is NT$58,583
NT$65,027 total
includes taxes & fees
May 26 - May 27
Portrait Firenze - Lungarno Collection

Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection
5.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (619 reviews)
"Staff was amazing! Location is the best"
United States
Jimmy
The price is NT$36,614
NT$40,861 total
includes taxes & fees
Jun 3 - Jun 4
Hotel Lungarno - Lungarno Collection

Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (198 reviews)
"Great stay, wonderful and helpful staff. Thank you!"
United Kingdom
Amena
The price is NT$11,783
NT$13,474 total
includes taxes & fees
Jun 14 - Jun 15
Leone Blu Suites | UNA Esperienze

Hotel Milu Florence

Hotel Milu Florence
4.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (635 reviews)
"Great stay, thanks Wonderful location and breakfasts were the best!"
United States
Filipe
The price is NT$13,451
NT$15,858 total
includes taxes & fees
Jun 8 - Jun 9
Hotel Milu Florence

IL Tornabuoni The Unbound Collection by Hyatt

IL Tornabuoni The Unbound Collection by Hyatt
5.0 star property
Duomo, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (121 reviews)
"Great location very nice hotel and friendly staff"
United States
Katrena
The price is NT$19,073
NT$21,566 total
includes taxes & fees
May 31 - Jun 1
IL Tornabuoni The Unbound Collection by Hyatt

Davanzati

Davanzati
3.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (905 reviews)
"Everything was lovely. "
United Kingdom
olga
The price is NT$8,966
NT$10,302 total
includes taxes & fees
Jun 21 - Jun 22
Davanzati

Antica Torre di Via Tornabuoni 1

Antica Torre di Via Tornabuoni 1
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (591 reviews)
"This was an absolute great place !"
United States
Erika
The price is NT$16,277
NT$18,344 total
includes taxes & fees
Jun 9 - Jun 10
Antica Torre di Via Tornabuoni 1

Al Palazzo del Marchese di Camugliano

Al Palazzo del Marchese di Camugliano
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (350 reviews)
"The location is good for sight seeing and the staff are very friendly but I could not sleep. Our room (Stella) was so noisy, I could hear everything happening on the street and the revelry went on until 3am each night."
United Kingdom
Amy
The price is NT$13,959
NT$15,795 total
includes taxes & fees
Jun 3 - Jun 4
Al Palazzo del Marchese di Camugliano

Golden Tower Hotel & Spa

Golden Tower Hotel & Spa
5.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (984 reviews)
"Great location."
United States
Cynthia
The price is NT$18,334
NT$20,753 total
includes taxes & fees
Jun 21 - Jun 22
Golden Tower Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Piazza Santo Spirito Hotel Reviews

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Frequently asked questions

What's the area like around Piazza Santo Spirito?
Piazza Santo Spirito is located in a historic area of Florence known for its stunning cathedral and popular art scene. If you're looking for a convenient place to stay, check out the 3070 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Piazza Santo Spirito?
Adjacent to Piazza Santo Spirito, B&B Hotel Firenze Pitti Palace al Ponte Vecchio is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a bar. Other good choices close by include Hotel Paris and Hotel Calimala Florence.
How many hotels should I expect to find close to Piazza Santo Spirito?
Expedia has 3070 hotels and other accommodations within a mile from Piazza Santo Spirito.
If I need to cancel the hotel reservation for my stay near Piazza Santo Spirito, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best options available near Piazza Santo Spirito.
Where can I learn more about changing or cancelling my trip in the area near Piazza Santo Spirito?
For more details about updating your stay near Piazza Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do near Piazza Santo Spirito?
Study the collections at Uffizi Gallery, Salvatore Ferragamo Museum, or Galileo Museum - Institute and Museum of the History of Science. Ponte Vecchio, Pitti Palace, and Via de' Tornabuoni are landmarks that you won't want to miss. You can check out the local talent at Teatro Comunale Florence, Visarno Arena, and Opera Teatro Auditorium al Duomo.
How can I get to Piazza Santo Spirito?
With so many transportation options, seeing the area around Piazza Santo Spirito is simple. Walk to nearby metro stations like Unità Tram Stop, Valfonda - Stazione Santa Maria Novella Tram Stop, and San Marco University Tram Stop. If you're taking a train into town, Florence (ZMS-Santa Maria Novella Train Station) and Florence Santa Maria Novella Station are the closest stops to Historic Centre of Florence.