
Find hotels in Matlacha Isles, Cape Coral
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Matlacha Isles hotels

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach20.4 km from Matlacha Isles
8.8 out of 10, Excellent, (1,002 reviews)
The price is NT$4,973
NT$5,545 total
includes taxes & fees
Jan 29 - Jan 30

Latitude 26 Waterfront Resort & Marina
Latitude 26 Waterfront Resort & Marina20.3 km from Matlacha Isles
8.6 out of 10, Excellent, (930 reviews)

Edison Beach House
Edison Beach House22.6 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,631 reviews)

Marriott Sanibel Harbour Resort & Spa
Marriott Sanibel Harbour Resort & Spa17.2 km from Matlacha Isles
8.4 out of 10, Very Good, (1,006 reviews)
The price is NT$12,283
NT$14,485 total
includes taxes & fees
Jan 28 - Jan 29

Holiday Inn Fort Myers - Downtown Area by IHG
Holiday Inn Fort Myers - Downtown Area by IHG17.8 km from Matlacha Isles
7.8 out of 10, Good, (1,006 reviews)
The price is NT$4,470
NT$4,984 total
includes taxes & fees
Jan 29 - Jan 30

Lani Kai Beachfront Resort
Lani Kai Beachfront Resort23.2 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,160 reviews)
The price is NT$7,076
NT$8,594 total
includes taxes & fees
Jan 27 - Jan 28

The Westin Cape Coral Resort At Marina Village
The Westin Cape Coral Resort At Marina VillagePelican, 12.3 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,011 reviews)
The price is NT$7,233
NT$9,328 total
includes taxes & fees
Feb 8 - Feb 9

Residence Inn by Marriott Fort Myers Sanibel
Residence Inn by Marriott Fort Myers Sanibel18.1 km from Matlacha Isles
8.6 out of 10, Excellent, (1,002 reviews)
The price is NT$5,526
NT$6,161 total
includes taxes & fees
Jan 27 - Jan 28

DiamondHead Beach Resort
DiamondHead Beach Resort23.5 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,045 reviews)

Best Western Fort Myers Waterfront
Best Western Fort Myers WaterfrontHancock, 16.7 km from Matlacha Isles
7.4 out of 10, Good, (1,006 reviews)
The price is NT$4,268
NT$4,758 total
includes taxes & fees
Jan 27 - Jan 28

Margaritaville Beach Resort Fort Myers
Margaritaville Beach Resort Fort Myers23 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,825 reviews)
The price is NT$8,497
NT$11,059 total
includes taxes & fees
Jan 27 - Jan 28

Boca Grande Hotel
Boca Grande Hotel28.8 km from Matlacha Isles
8.8 out of 10, Excellent, (592 reviews)
The price is NT$4,894
NT$5,482 total
includes taxes & fees
Jan 27 - Jan 28

Holiday Inn Express & Suites Punta Gorda by IHG
Holiday Inn Express & Suites Punta Gorda by IHG28.8 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,003 reviews)
The price is NT$4,800
NT$5,376 total
includes taxes & fees
Feb 1 - Feb 2

Hampton Inn & Suites Fort Myers - Colonial Blvd
Hampton Inn & Suites Fort Myers - Colonial Blvd21 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,001 reviews)
The price is NT$4,561
NT$5,085 total
includes taxes & fees
Feb 8 - Feb 9

Crowne Plaza Ft. Myers Gulf Coast by IHG
Crowne Plaza Ft. Myers Gulf Coast by IHG30.2 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,001 reviews)
The price is NT$7,862
NT$8,767 total
includes taxes & fees
Jan 29 - Jan 30

Dolphin Key Resort
Dolphin Key ResortCaloosahatchee, 13.7 km from Matlacha Isles
8.8 out of 10, Excellent, (1,227 reviews)
The price is NT$5,400
NT$6,020 total
includes taxes & fees
Jan 27 - Jan 28

Knights Inn Punta Gorda
Knights Inn Punta Gorda28.5 km from Matlacha Isles
7.2 out of 10, Good, (957 reviews)
The price is NT$2,846
NT$3,188 total
includes taxes & fees
Jan 27 - Jan 28

Luminary Hotel & Co., Autograph Collection
Luminary Hotel & Co., Autograph Collection17.8 km from Matlacha Isles
9.2 out of 10, Wonderful, (493 reviews)
The price is NT$10,862
NT$12,111 total
includes taxes & fees
Feb 8 - Feb 9

Comfort Inn Fort Myers Northeast
Comfort Inn Fort Myers Northeast25.8 km from Matlacha Isles
7.8 out of 10, Good, (685 reviews)
The price is NT$3,999
NT$4,459 total
includes taxes & fees
Jan 28 - Jan 29

Best Western Fort Myers Inn & Suites
Best Western Fort Myers Inn & Suites20.8 km from Matlacha Isles
8.8 out of 10, Excellent, (1,136 reviews)
The price is NT$3,353
NT$3,739 total
includes taxes & fees
Feb 1 - Feb 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most.

Pelican
If you're spending some time in Pelican, Tarpon Point and Chabad Jewish Center are top sights worth seeing.

Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Yacht Club
While there might not be top attractions in Yacht Club, you can explore the larger area and discover places like Cape Coral Yacht Club Beach and Dolphin Marina.
Mariner
While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area.

Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Top Matlacha Isles Hotel Reviews

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- Fort Myers Hotels
- Hotels near Harborside Event Center
- Pet-Friendly Hotels in Cape Coral
- Hotels near Lynn Hall Memorial Park
- Hotels near McCarthy's Marina
- Hotels near Bunche Beach
- Hotels near Eagle Ridge Golf Club
- Hotels with a Pool in Matlacha
- 5 Star Hotels in North Captiva
- Beach Hotels in Safety Harbor Club
- Hotels near Sanibel and Captiva Island Visitor's Center
- Hotels near Useppa Island
- Hotels with a Lazy River in Cape Coral
- Hotels near Bowman's Beach
- Hotels near Edison Mall
- Shopping Hotels in Cape Coral
- Hotels near Coral Oaks Golf Course
- Beach Hotels in Captiva
- Family Hotels in Fort Myers
- Hotels near Gasparilla Island State Park
- Fort Myers River District Hotels
- Beach Hotels in Fort Myers
- 5 Star Hotels in North Fort Myers
- Beach Hotels in North Captiva
- Hotels with a Pool in Punta Rassa
- Villas in Cape Coral
- Hotels near San Carlos Golf Club
- Hotels near Butterfly Estates
- Adventure Hotels in Fort Myers
- Hotels with Bars in Cape Coral
- Hotels near Fort Myers Country Club
- Vacation Homes in Florida Gulf Coast
- Hotels near Lee Civic Center
- Luxury Hotels in Fort Myers
- Fort Myers Beach Hotels
- Hotels near Bell Tower Shops
- Resorts & Hotels with Spas in Cape Coral
- Hotels near City of Palms Park
- Boutique Hotels in Cape Coral
- Pet-Friendly Hotels in Matlacha
- Hotels near Boca Grande Historical Society and Museum
- Hotels near Del Tura Golf and Country Club
- Hotels near Pine Island Shopping Center
- Hotels near Sanibel Harbour Beach
- All-Inclusive Hotel Hotels in Fort Myers
- Resorts in Fort Myers
- Hotels with a Pool in Cape Coral
- Wyndham Hotels in Florida Gulf Coast
- Hotels near Edison and Ford Winter Estates
- Hotels near Shell Factory and Nature Park
- 5 Star Hotels in Cape Coral
- 4 Star Hotels in Cape Coral
- 4 Star Hotels in North Captiva
- Hotels near Legends Golf and Country Club
- Hotels near Alison Hagerup Beach Park
- Adults Only Resorts & in Cape Coral
- Hotels near Periwinkle Way
- Sunstream Hotels in Bokeelia
- Fort Myers Historical Museum
- Dolphin Marina
- Lovegrove Gallery & Gardens
- Visit Lee County
- Fort Myers Vacations
- Sanibel Harbour Beach
- Edison and Ford Winter Estates
- Cypress Lake Country Club
- Visit Captiva Island
- Visit Matlacha
- City of Palms Park
- Thomas Edison Congregational Church
- Visit Punta Rassa
- Edison Mall
- Visit Cape Coral
- El Rio Golf Club
- Bunche Beach
- Visit Bokeelia
- Cape Coral Vacations
- Mex Rent A Car Rental Cars in Burnt Store Marina
- Car rental Cape Coral
- Europcar Rental Cars in Safety Harbor Club
- Ok Mobility Rental Cars in Captiva
- Surprice Car Rentals Rental Cars in Burnt Store Marina
- Enterprise Rental Cars in Pine Manor
- Dollar Rental Cars in Pine Island
- Dollar Rent A Car Rental Cars in Fort Myers
- Avis Rental Cars in Cape Coral
- Avis Rental Cars in Metro Park
- Thrifty Car Rental Rental Cars in Fort Myers
- Car rentals near Mike Greenwell's Bat-A-Ball & Family Fun Park
- National Car Rental Rental Cars in Moody River Estates















































































