Matlacha Isles Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to NT$25,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles
Sunset on Fort Myers Beach

Pelican

1 out of top 10 points of interest in this area
4.5/5(47 area reviews)

If you're spending some time in Pelican, Tarpon Point and Chabad Jewish Center are top sights worth seeing.

Find hotels in Pelican

Matlacha Isles Hotel Deals

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is NT$8,123 per night from Jun 3 to Jun 4
NT$8,123
NT$10,155 total
Jun 3 - Jun 4
includes taxes & fees
8.6/10 Excellent! (1,007 reviews)
"The staff of the hotel made us feel very special since it was our anniversary. Champagne and strawberries were sent to our suite. Would highly recommend it."

Reviewed on 2026/5/31

Marriott Sanibel Harbour Resort & Spa
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is NT$2,227 per night from Jun 28 to Jun 29
NT$2,227
NT$2,483 total
Jun 28 - Jun 29
includes taxes & fees
6.8/10 (1,094 reviews)
"Excellent😃 and clean to my point of view"

Reviewed on 2026/5/31

Baymont by Wyndham Fort Myers Central
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is NT$6,464 per night from Jun 14 to Jun 15
NT$6,464
NT$8,781 total
Jun 14 - Jun 15
includes taxes & fees
9/10 Wonderful! (2,154 reviews)
"I liked the staff willing to help idint like at all that they changed 35 dollars a day for parking in the hotel as a guest i think that's a bad advertisement for quest"

Reviewed on 2026/5/31

Margaritaville Beach Resort Fort Myers
See all 14,737 properties in Matlacha Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Matlacha Isles vacation package cost?
Our Matlacha Isles vacation packages, which begin from just , are the best way to save loads of cash. Select your favorite flights, hotels and rental cars to create a custom-built itinerary.
How do I get a cheap travel package to Matlacha Isles?
Combine your hotel and flight bookings, add on extras such as activities, and save with a Matlacha Isles vacation package. You won't just walk away with awesome discounts on your trip — you'll have loads of choice at your fingertips too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 hotels around the globe. Your next epic adventure begins right here, right now!
Where should I stay in Matlacha Isles?
If you're itching to be where the action is, stay near Sun Splash Water Park. Many happy campers book a hotel around this renowned tourist attraction.
What are the top hotels in Matlacha Isles?
Reserve a room at The Perfect Day In Matlacha Direct Gulf Access. It's one of the neighborhood's most popular hotels. Another highly rated option in Matlacha Isles is Fun'n Sun - Charming 3 Br/ 3 Baths Waterfront Villa W. Boat Lift.
How far in advance should I book my Matlacha Isles vacation?
Smart travelers will likely want to reserve their seats early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you've left things to the last minute, don't stress. Low prices occasionally become available just weeks prior to departure.
What does an Expedia Matlacha Isles travel package include?
Expedia has all you need to organize your Matlacha Isles trip, but how you structure your package depends on you. Select from a combination of rental cars, hotels and flights. Chasing some experiences or tours to keep you busy? Once you've made your booking, you can add them on too. No matter your budget, there's a deal to suit your needs.
What should I know before booking a Matlacha Isles travel package?
Bundling your bookings into a Matlacha Isles vacation package is the easiest way to organize your trip. Not only that, you'll save just for combining your hotels, flights and car rentals. Once you've booked, why not add on a day tour or an activity?
Can I choose my airline with a Matlacha Isles Expedia vacation package?
Yes, definitely. Expedia has more than 550 partner airlines to select from globally. With all that choice, finding the ideal carrier to bring you to Matlacha Isles will be easy.
If I'm not able to travel, can I cancel my Matlacha Isles vacation package?
Don't worry if you're rethinking your Matlacha Isles vacation package — you can cancel or change your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We get that your circumstances can suddenly change, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Discover the most popular places to visit in Matlacha Isles

St. Augustine, Florida. January 26 , 2019. Sailboat and Bridge of Lions in Florida's Historic Coast

Dolphin Marina

Explore the waterfront of Dolphin Marina and enjoy other activities such as boating in Cape Coral. Wander the beautiful beaches and seaside in this family-friendly area.

Dolphin Marina

Lee Island

Explore the great outdoors at Lee Island and enjoy the beautiful sunsets during your trip to Cape Coral. Amble around this family-friendly area's beautiful beaches and enjoy its lively bars.

Lee Island

Fort Myers Shopping Center

You can find the perfect gifts to bring home at Fort Myers Shopping Center during your visit to North Fort Myers. Stroll along the beautiful beaches or attend a baseball game in the area.

Fort Myers Shopping Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.