Find hotels in South Central Houston, Houston from NT$1,627

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Discover 1,142 South Central Houston hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very Good, (1431)
"Conveniently located and excellent property. "
The price is NT$3,024
NT$3,571 total
includes taxes & fees
Jul 20 - Jul 21
Hilton Houston Plaza/Medical Center

InterContinental Houston by IHG

4.0 star property
9.2 out of 10, Wonderful, (1002)
"Great Place"
The price is NT$4,065
NT$5,340 total
includes taxes & fees
Jul 13 - Jul 14
InterContinental Houston by IHG

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.2 out of 10, Very Good, (378)
"Very nice place clean nice towels good shower"
The price is NT$3,135
NT$3,668 total
includes taxes & fees
Jul 20 - Jul 21
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1718)
"Great stay!"
The price is NT$5,430
NT$7,538 total
includes taxes & fees
Aug 10 - Aug 11
Hotel Zaza Houston Museum District

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1002)
"Peaceful and relaxing stay."
The price is NT$4,449
NT$6,142 total
includes taxes & fees
Aug 8 - Aug 9
Houston Marriott Medical Center/Museum District

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1007)
"Very clean and peaceful place to stay close to the hospital 🏥 "
The price is NT$2,342
NT$2,749 total
includes taxes & fees
Jul 12 - Jul 13
Extended Stay America Suites Houston Med Ctr Braeswood Bl

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1019)
"Great place to stay "
The price is NT$4,228
NT$5,262 total
includes taxes & fees
Jul 19 - Jul 20
The Westin Houston Medical Center/Museum District

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (1002)
"Highly recommended.. I will stay again."
The price is NT$2,420
NT$2,831 total
includes taxes & fees
Jul 12 - Jul 13
Americas Best Value Inn Medical Center Downtown

Wanderstay Houston Hostel

2.0 star property
8.4 out of 10, Very Good, (183)
"This is an amazing place to stay."
The price is NT$1,749
NT$2,046 total
includes taxes & fees
Jul 14 - Jul 15
Wanderstay Houston Hostel

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (510)
"Nice property we are enjoying our stay. "
The price is NT$5,218
NT$6,105 total
includes taxes & fees
Jul 17 - Jul 18
La Maison in Midtown an urban B&B

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (839)
"Awesome Hotel. "
The price is NT$4,683
NT$5,479 total
includes taxes & fees
Jul 16 - Jul 17
Hilton University of Houston

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (189)
"This was a wonderful place to stay!!"
The price is NT$6,034
NT$7,301 total
includes taxes & fees
Jul 13 - Jul 14
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Rodeway Inn & Suites Houston near Medical Center

2.0 star property
6.2 out of 10, (470)
"It was affordable and comfortable. "
The price is NT$1,627
NT$1,903 total
includes taxes & fees
Jul 12 - Jul 13
Rodeway Inn & Suites Houston near Medical Center

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (216)
"Good area"
The price is NT$1,895
NT$2,217 total
includes taxes & fees
Jul 12 - Jul 13
Southmore Boulevard Motel

Newly Built Modern 3 Bedroom Houston Home

2.0 star property
10.0 out of 10, Exceptional, (1)
Newly Built Modern 3 Bedroom Houston Home

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
Posh Dtwn Midtown Home w Stunning Roof-topterrace

Modern Cozy Home with King Bed

3.5 star property
9.6 out of 10, Exceptional, (16)
"Everything was great, beautiful view! "
The price is NT$3,935
NT$10,143 total
includes taxes & fees
Jul 29 - Jul 30
Modern Cozy Home with King Bed

Wanderstay Boutique Hotel

2.0 star property
9.8 out of 10, Exceptional, (39)
"Great stay!"
The price is NT$3,678
NT$4,304 total
includes taxes & fees
Jul 15 - Jul 16
Wanderstay Boutique Hotel

Luxury Med Center Fully Equipped King Sized Bed Condos

4.0 star property
8.4 out of 10, Very Good, (92)
"Facility was nice. DRIFTRS, the management company, is really bad. We were there for 4 days. Upon arrival we noticed no toilet paper and half the light bulbs burned out. The place was so dark I needed a flashlight to use the kitchen. We reported these issues immediately. They told us to use kitchen paper towels as toilet paper and did not respond to all the burned out light bulbs. We woke up every morning with the apartment hot and stuffy. The NEST thermostat is programmed to continually...
The price is NT$4,476
NT$8,014 total
includes taxes & fees
Jul 16 - Jul 17
Luxury Med Center Fully Equipped King Sized Bed Condos

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
The price is NT$9,024
NT$18,846 total
includes taxes & fees
Jul 14 - Jul 15
Paradise Palace Best Rooftop in HTX w Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.
Downtown Houston map

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria map

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center map

Texas Medical Center

2 out of top 10 points of interest in this area

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose map

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Frequently asked questions

What's it like in South Central Houston?

Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighborhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other favorite options in the area include La Maison in Midtown an urban B&B and The Westin Houston Medical Center/Museum District.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1146 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.

Where can I learn more about changing or cancelling my trip to South Central Houston?

To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.

What is there to do around this Houston neighborhood?

Spend some time exploring the great outdoors at Hermann Park, James Turrell's Twilight Epiphany Skyscape, and Cullen Sculpture Garden. Houston Zoo and Children's Museum of Houston are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station.