The Best Hotels Closest to El Machetazo Santa Ana in Panama City for 2026

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Our top choices for El Machetazo Santa Ana hotels

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

A four-poster bed with a black and white bedspread, two bedside tables with lamps, and a robe hanging on a rack.

A living room with a sofa, a coffee table with books, a chandelier, and a kitchen with wooden cabinets and granite countertops.

A room with a large window, a television mounted on the wall, and two chairs.

1. La Isabela Suites

San Felipe, 0.3 km from El Machetazo Santa Ana

David

NT$5,001

NT$5,502 total

includes taxes & fees

Sep 29 - Sep 30

A restaurant with multiple dining tables, chairs, and a central water feature.

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

A bar area with multiple seating options, a bar counter, and a fireplace.

A historic building with ornate stonework and a balcony with plants.

2. Hotel La Compañía Casco Antiguo

San Felipe, 0.5 km from El Machetazo Santa Ana

Reid

NT$8,880

NT$9,768 total

includes taxes & fees

Sep 29 - Sep 30

A multi-story building with ornate balconies, large windows, and decorative moldings.

A spacious hotel room with a large bed, a seating area with a sofa and chairs, a dining table, and a staircase.

A luxurious room with ornate chandeliers, a large mirror, and a bar area with shelves of bottles.

A spacious restaurant with high wooden ceilings, multiple tables and chairs, and a bar area with shelves of bottles and glasses.

3. Hotel Plaza Herrera

San Felipe, 0.4 km from El Machetazo Santa Ana

Christina

NT$6,495

NT$7,145 total

includes taxes & fees

Sep 29 - Sep 30

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

A hotel with a rooftop pool, lounge chairs, and a view of the sea.

A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

4. Sofitel Legend Casco Viejo, Panama City

San Felipe, 0.8 km from El Machetazo Santa Ana

Jose

NT$12,575

NT$13,832 total

includes taxes & fees

Oct 6 - Oct 7

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A white building with multiple balconies, large windows, and decorative railings.

A spacious lobby with a tiled floor, large windows, and potted plants.

A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

5. American Trade Hotel

San Felipe, 0.4 km from El Machetazo Santa Ana

Caroline

NT$5,692

NT$6,261 total

includes taxes & fees

Oct 12 - Oct 13

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

A glass of white wine on a balcony railing overlooking a city street with buildings and cars.

A restaurant interior with a large indoor tree, tables, chairs, and a display of potted plants.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

6. La Concordia Boutique Hotel

San Felipe, 0.2 km from El Machetazo Santa Ana

Jadah

NT$6,400

NT$7,040 total

includes taxes & fees

Oct 8 - Oct 9

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A hotel with a covered entrance, multiple windows, and a balcony with plants.

A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.

A modern bar area with wooden bar stools, a black countertop, and a display of wine bottles.

7. Hotel San Felipe

San Felipe, 0.4 km from El Machetazo Santa Ana

Rebecca

NT$4,484

NT$4,933 total

includes taxes & fees

Oct 1 - Oct 2

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

A rooftop terrace with a hot tub, wooden deck, outdoor seating, and a view of a cityscape including a clock tower.

A room with a brick wall, a wooden staircase, and hanging pendant lights.

A multi-level interior with a checkered floor, wooden railings, and potted plants.

8. Amarla Boutique Hotel Casco Viejo Adults Only

San Felipe, 0.6 km from El Machetazo Santa Ana

Shanae

NT$7,502

NT$8,252 total

includes taxes & fees

Sep 30 - Oct 1

A multi-story building with balconies, large windows, and a clear blue sky.

A hallway with a brick wall, a blue door, and a chair with a cushion.

A living room with a sofa, a dining table with chairs, a potted plant, and a rug.

A hotel room with a brick wall, a large window with curtains, a bed with pillows, a nightstand, and a chair.

9. Las Clementinas

San Felipe, 0.2 km from El Machetazo Santa Ana

James

NT$4,818

NT$5,935 total

includes taxes & fees

Oct 13 - Oct 14

A multi-story building with balconies, arched windows, and decorative railings.

A building with a balcony and a street view.

A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

10. Central Hotel Panama Casco Viejo

San Felipe, 0.5 km from El Machetazo Santa Ana

Olga

NT$6,039

NT$6,643 total

includes taxes & fees

Sep 29 - Sep 30

A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

A buffet setup with various dishes and utensils.

A spacious lobby with high ceilings, large windows, and modern lighting fixtures.

A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

11. Marriott Panama Hotel

2.4 km from El Machetazo Santa Ana

Richard

NT$5,367

NT$5,903 total

includes taxes & fees

Oct 10 - Oct 11

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A blue building with arched windows and balconies, labeled 'Magnolia.'

A bedroom with a large bed, white walls, and a view of a building through arched windows.

12. Hotel Magnolia Boutique

San Felipe, 0.4 km from El Machetazo Santa Ana

Boris

NT$2,567

NT$2,824 total

includes taxes & fees

Sep 30 - Oct 1

A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.

A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.

A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.

13. Bristol Panama, a Registry Collection Hotel

Bella Vista, 3.2 km from El Machetazo Santa Ana

Juliet

NT$6,721

NT$7,393 total

includes taxes & fees

Oct 2 - Oct 3

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

A restaurant interior with tables and chairs, decorative hanging lights, and a mural on the wall.

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

14. Tantalo Hotel

San Felipe, 0.4 km from El Machetazo Santa Ana

Cassondra

NT$2,409

NT$2,650 total

includes taxes & fees

Oct 4 - Oct 5

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A modern kitchen with a central island, stainless steel appliances, and a dining area with black chairs.

A modern bedroom with a large window, a bed with white linens, a nightstand, and a painting on the wall.

A balcony with a view of the sea, a table with a vase and a candle, and a chair.

15. Casco View Life Residences

Santa Ana, 0.2 km from El Machetazo Santa Ana

Ruben

NT$2,483

NT$3,684 total

includes taxes & fees

Oct 8 - Oct 9

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A balcony with a view of a city skyline, a river, and a large tree.

A living room with a patterned sofa, a matching ottoman, a large mirror, and a staircase leading to an outdoor area.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

16. Hotel Bardot Boutique

San Felipe, 0.8 km from El Machetazo Santa Ana

Gary

NT$2,554

NT$2,809 total

includes taxes & fees

Oct 4 - Oct 5

A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.

A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.

A high-rise building with a rooftop pool area, surrounded by other buildings.

17. W Panama

Campo Alegre, 3.2 km from El Machetazo Santa Ana

Naomi

NT$8,358

NT$9,194 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel pool area with lounge chairs and a clear view of the ocean.

A modern bar area with seating and a view of the city.

A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.

A modern interior with a spiral staircase, a large window, and a seating area.

18. Hilton Panama

Bella Vista, 3 km from El Machetazo Santa Ana

Kevin

NT$7,786

NT$8,564 total

includes taxes & fees

Oct 24 - Oct 25

An outdoor patio area with wicker furniture and glass-top tables, surrounded by lush greenery and a view of the interior.

A living room with wicker furniture, a television, and a sliding glass door leading to a balcony with plants.

A rectangular swimming pool with a tiled edge, surrounded by a tiled patio area.

A garden with a concrete pathway, various plants, and a birdcage.

19. The Balboa Inn

Balboa, 1.7 km from El Machetazo Santa Ana

Rhonda

NT$2,338

NT$2,572 total

includes taxes & fees

Sep 29 - Sep 30

A modern bathroom with a glass shower enclosure, a wooden door, and a herringbone-patterned floor.

A modern bathroom with a glass shower enclosure, a herringbone wooden floor, and a stone wall feature.

A multi-story building with balconies adorned with string lights, a sign reading "ZABAH", and a storefront named "CORCHO".

20. Corcho

San Felipe, 0.4 km from El Machetazo Santa Ana

Ashley

NT$2,598

NT$2,858 total

includes taxes & fees

Sep 29 - Sep 30

View all properties

Compare popular hotels close to El Machetazo Santa Ana

Property	Property class	Guest rating
La Isabela Suites	10.0 Exceptional 212 reviews	View
Hotel La Compañía Casco Antiguo	9.8 Exceptional 353 reviews	View
Hotel Plaza Herrera	9.8 Exceptional 49 reviews	View
Sofitel Legend Casco Viejo, Panama City	9.8 Exceptional 751 reviews	View
American Trade Hotel	9.4 Exceptional 816 reviews	View

Top El Machetazo Santa Ana Hotel Reviews

Hotel Magnolia Boutique

8/10 Good

"The room was clean bed comfy the front staff wad exceptional very friendly an very helpful cant say enough about the front desk staff they made the stay great I would definitely stay here again my one suggestion would be a small refrigator in the room an a lock box my friend room had lock box mine didn't had to share his other than that great spot right in the middle of everything"

American Trade Hotel

8/10 Good

"Nice hotel and beautiful room with terrace facing the square. Difficulty entering the room halfway through my one night stay which involved several trips to the reception after being told the batteries in the door needed changing. Should really have been sorted at maintenance. Communication between staff not great as despite being allowed a late checkout, cleaning staff came repeatedly banging on the door in that last hour."

Hotel Caracas - Casco Viejo

10/10 Excellent

"We stayed one night there. Very comfortable location. The room was clean, nice shower, helpful and friendly staff, and they have good coffee in the lobby :)"

Hostal La Cigarra

8/10 Good

"Location is great, very comfortable and the instructions sent before the stay were useful. The room is clean and functional, and the stuff is very kind and helpful. The only thing to say is that there is no hot water in the shower, something that I expect to be informed about before booking the room."

Hotel San Felipe

10/10 Excellent

"This property is set in a great location and is very cute and clean. The bed was great. The staff was very nice and efficient without being overwhelming. We didn't eat at the restaurant because we did a lot of exploring but would definitely stay again. The only thing I would say needs some improvement is the wifi strength it wasn't always reliable."

Sofitel Legend Casco Viejo, Panama City

10/10 Excellent

"Sofitel Legend is a wonderful place to stay. The staff are amazing."

Hotel Casa Panamá

8/10 Good

"Overall a good place to stay for exploring Panama. Lots of restaurants and activities walking distance."

La Concordia Boutique Hotel

10/10 Excellent

"Location was excellent, in the thick of things in Casco Viejo and walking distance to a wide variety of shops and restaurants. The rooftop restaurant was very nice though we didn’t eat there. Our room was large, with a huge bathroom, huge shower, and double sinks. Decor was wonderful. Highly recommended."

Casco View Apartments

10/10 Excellent

"We really enjoyed our stay at Casco View. It was an easy walk into Casca Viejo and centrally located. The host uses a guesty app to provide room details, apartment codes, etc, so it was a really easy and smooth process to get checked in. The room itself was very clean and well appointed. We stayed on the 6th floor, which is also the floor with the pool, which offered really great views of the surrounding areas. Honestly, the hotel is a very sleek and modern building, surrounded by some rougher buildings. Don't let that deter you though - we felt very safe coming and going, even late at night, and it's only a block or so Santa Ana square. It was a great stay and we'd definitely consider it again next time we stay in Casco Viejo area."

Other attractions near El Machetazo Santa Ana

Amador Theater

Enjoy a show at Amador Theater, a storied theater in Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Iglesia de la Merced

You can learn about the history of Panama City with a stop at Iglesia de la Merced. Check out the shops and top-notch restaurants in this vibrant area.

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Danilo Perez Foundation

Explore the campus of Danilo Perez Foundation as part of your travels around Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Mola Museum

You can spend time browsing the exhibits at Mola Museum during your trip to Panama City. You can enjoy the bars while in the area.

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Museo de la Esmeralda

You can spend time exploring the galleries in Museo de la Esmeralda during your trip to Panama City. You can enjoy the bars while in the area.

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Palacio de las Garzas

You can study the exhibits at Palacio de las Garzas, a museum with a storied past, during your trip to Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Metropolitan Cathedral of Panama

9.0/10 (793 reviews)

Metropolitan Cathedral of Panama is just one of the places to see in Panama City, so why not enjoy the other things to explore during your travels? Check out the shops and top-notch restaurants in this vibrant area.

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Independence Square

9.0/10 (62 reviews)

You can learn about the history of Panama City with a stop at Independence Square. Check out the shops and top-notch restaurants in this vibrant area.

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Frequently asked questions

What's the area like around El Machetazo Santa Ana?

El Machetazo Santa Ana is located in Panama City. If you're looking for a convenient place to stay, check out the 517 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to El Machetazo Santa Ana?

Adjacent to El Machetazo Santa Ana, Hotel Casa Panamá is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and a nightclub. Other good options close by include Central Hotel Panama Casco Viejo and Sofitel Legend Casco Viejo, Panama City.

How many hotels are there close to El Machetazo Santa Ana?

Expedia has 517 hotels and other accommodations within a mile from El Machetazo Santa Ana.

If I need to cancel the hotel reservation for my stay near El Machetazo Santa Ana, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best options available near El Machetazo Santa Ana.

Where can I learn more about changing or cancelling my trip in the area near El Machetazo Santa Ana?

To access more information about rescheduling or cancelling your stay near El Machetazo Santa Ana, go to https://www.expedia.com/service/.

What can I see and do near El Machetazo Santa Ana?

You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo, and Mola Museum. Explore landmarks like Iglesia del Carmen, Panama Canal Railway, and Iglesia de la Merced. You can check out the local talent at National Theater, Amador Theater, and Anita Villalaz Theater.

Find hotels near El Machetazo Santa Ana, Panama City from NT$2,572

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for El Machetazo Santa Ana hotels

1. La Isabela Suites

2. Hotel La Compañía Casco Antiguo

3. Hotel Plaza Herrera

4. Sofitel Legend Casco Viejo, Panama City

5. American Trade Hotel

6. La Concordia Boutique Hotel

7. Hotel San Felipe

8. Amarla Boutique Hotel Casco Viejo Adults Only

9. Las Clementinas

10. Central Hotel Panama Casco Viejo

11. Marriott Panama Hotel

12. Hotel Magnolia Boutique

13. Bristol Panama, a Registry Collection Hotel

14. Tantalo Hotel

15. Casco View Life Residences

16. Hotel Bardot Boutique

17. W Panama

18. Hilton Panama

19. The Balboa Inn

20. Corcho

Compare popular hotels close to El Machetazo Santa Ana

Top El Machetazo Santa Ana Hotel Reviews

Hotel Magnolia Boutique

American Trade Hotel

Hotel Caracas - Casco Viejo

Hostal La Cigarra

Hotel San Felipe

Sofitel Legend Casco Viejo, Panama City

Hotel Casa Panamá

La Concordia Boutique Hotel

Casco View Apartments

Other attractions near El Machetazo Santa Ana

Amador Theater

Iglesia de la Merced

Danilo Perez Foundation

Mola Museum

Museo de la Esmeralda

Palacio de las Garzas

Metropolitan Cathedral of Panama

Independence Square

Frequently asked questions