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Our top choices for Cairo hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (291 reviews)
"Breakfast was sparse. This motel needs a complete overhaul. "
United States
Susan
The price is NT$2,177
NT$2,416 total
includes taxes & fees
Jul 24 - Jul 25
Quality Inn Cairo I-57

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (647 reviews)
"Clean rooms,"
United States
Karl
The price is NT$1,915
NT$2,125 total
includes taxes & fees
Jul 12 - Jul 13
Super 8 by Wyndham Charleston/Sikeston East MO

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (420 reviews)
"Wanted to use the pool, but had debris on the bottom and no (0) chairs to sit in."
United States
Robert
The price is NT$2,414
NT$2,679 total
includes taxes & fees
Jul 12 - Jul 13
The Riverstone Hotel Charleston-Sikeston

La Center Motel

La Center Motel
2.0 star property
La Center
7.4 out of 10, Good, (20 reviews)
"Property is located just outside of town, so very convenient yet slightly off the beaten path."
United States
Carrie
The price is NT$1,738
NT$2,033 total
includes taxes & fees
Jul 12 - Jul 13
La Center Motel

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
The price is NT$2,230
NT$2,475 total
includes taxes & fees
Aug 1 - Aug 2
Eagle Inn Charleston

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is NT$4,796
NT$9,350 total
includes taxes & fees
Aug 2 - Aug 3
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Cairo attractions

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town.

A steel bridge with a sunset in the background.

Top Cairo Hotel Reviews

More cheap stays in Cairo

Hotels in Cairo with star-rating

Find out more about Cairo

Top reasons to visit Cairo

  • Scenic Outdoor Adventures: Enjoy camping and riverboat tours that showcase the beautiful landscapes along the rivers.
  • Rich Historical Charm: Explore the historic forts and scenic streets that reflect Cairo's unique heritage.
  • Community Atmosphere: Experience local neighborhoods that offer a taste of the friendly community life.
  • Diverse Accommodations: Choose from a range of pet-friendly and family-oriented lodging options for a comfortable stay.
  • Family-Friendly Activities: Cairo provides a variety of attractions suitable for visitors of all ages.

Find great hotels in and around Cairo

Discover a variety of accommodation options in Cairo, Illinois, perfect for every traveler. Whether you're looking for a cozy motel or a comfortable hotel, you'll find pet-friendly and family-oriented facilities to enhance your stay. Ideal for business trips or leisurely vacations, the local inns and motels cater to diverse needs, ensuring a pleasant experience in this charming riverside town.

  • Super 8 by Wyndham Charleston/Sikeston East MO: Located 16km from Cairo, Super 8 by Wyndham Charleston/Sikeston East MO offers a budget-friendly and family-oriented experience. This motel is ideal for travelers looking for a pet-friendly environment. It features amenities for children, including complimentary cribs available upon reservation, ensuring a comfortable stay for families. The property is also accommodating to pets, with specific policies in place for pets and service animals, making it a great choice for those traveling with their furry companions.
  • The Riverstone Hotel Charleston-Sikeston: Situated 19km from Cairo, The Riverstone Hotel Charleston-Sikeston caters to both business travelers and pet owners seeking budget-friendly lodging. The hotel provides a range of amenities tailored for business needs while maintaining a welcoming atmosphere for pets, with restrictions on dog breeds and weight. Service animals are welcome without fees, allowing for a seamless stay. Guests appreciate the balance of professional services and a comfortable environment, making it suitable for work and leisure.
  • Quality Inn Cairo I-57: Located right in Cairo, Quality Inn Cairo I-57 is a budget-friendly hotel that focuses on family and pet-friendly accommodations. Families can benefit from amenities like free cribs and a first aid kit for extra safety. The hotel allows pets with certain restrictions and deposits, ensuring a welcoming atmosphere for animal lovers. Its convenient location makes it a practical choice for those wanting to explore the local area while enjoying comfortable lodging.

Where to stay near Cairo

Cairo, Illinois, offers a unique blend of outdoor adventure and historical charm. Explore the scenic streets, where you can soak in the local atmosphere and discover family-friendly activities. Nearby neighborhoods provide a taste of community life, while local campgrounds invite you to connect with nature. Whether you're on a family holiday or a business trip, Cairo promises a memorable experience filled with diverse vibes and welcoming residents.

  • Wickliffe: Located a mere 10km from Cairo, Wickliffe is a charming city that offers a delightful blend of outdoor adventures and scenic beauty. This area is particularly popular from March to April and August, making it an ideal time for visitors seeking a romantic escape. Wickliffe boasts a variety of recreational areas and golf courses, perfect for those looking to enjoy the great outdoors. The nearby lakes and national state parks provide stunning landscapes and opportunities for hiking and picnicking, ensuring a memorable experience for nature lovers.
  • Mound City: Also situated 10km from Cairo, Mound City is a vibrant destination for those in search of adventure and romance. The city sees a peak in visitors during March, July, and October, drawing in outdoor enthusiasts and couples alike. Mound City features several recreational parks and golf venues, catering to those who enjoy active pursuits. The lush forests and picturesque lakes nearby offer excellent opportunities for exploration and relaxation, making it a fantastic spot for families and outdoor lovers to create lasting memories.
  • Wyatt: Just 11km away from Cairo, Wyatt is a family-friendly city that combines urban charm with outdoor fun. Visitor numbers peak during the warmer months from June to August, making it an excellent summer destination. Wyatt offers a variety of activities, including golf, dog parks, and urban parks, catering to both families and those looking for a city-themed experience. Moreover, event and conference venues in the area make it a great choice for travelers who wish to blend leisure with business during their stay.

Things to do in Cairo

Shopping

In Cairo, explore local shops and boutiques for unique gifts and souvenirs. If you're up for a drive, visit the nearby Town Center Plaza, located 19km away, featuring various retail stores and dining options to enhance your shopping experience.

Recreation

In Cairo, the Riverfront Wellness Center offers yoga classes with scenic views of the Mississippi River, promoting relaxation and mindfulness. Nearby, the Cairo Community Park features walking trails and picnic areas, ideal for leisurely strolls and outdoor activities amidst nature's beauty.

Adventure

Cairo, Illinois, offers a unique blend of history and nature. Explore the scenic trails at Fort Defiance State Park, where the confluence of the Mississippi and Ohio rivers provides stunning views. Visit the Cairo Public Library for intriguing local history, and enjoy the picturesque riverfront for a leisurely stroll.

Nightlife

Cairo offers a unique nightlife vibe with local bars like The Island View and live music venues such as The Cairo Jazz Company. Enjoy a laid-back evening at a cozy pub or catch a performance by local artists, immersing yourself in the community's artistic spirit.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Cairo

To save money during your visit to Cairo, Illinois, consider traveling between November and January for lower accommodation rates, with Tuesday being the cheapest day to book. Use Expedia's search tool to compare hotel prices and filter for eco-friendly options. For additional savings, bundle your hotel, flights, and activities in an Expedia package. Explore free attractions and utilize public transport to keep costs down. Remember that Saturdays are the most expensive days, so plan accordingly to maximize your budget.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Cairo are November to January, where the prices are slightly lower. This is in comparison to April to May and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Cairo is Tuesday. The most expensive day to stay in Cairo is Saturday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to customize your journey by selecting your budget, preferred location, and additional criteria. You can easily arrange your search results from the lowest to highest prices, ensuring that the most affordable hotels appear at the top. Additionally, you can refine your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking.
  • Consider bundling your trip: You can save money by combining your hotel stay in Cairo with your flights and activities through an Expedia package.

Find the best attractions in and around Cairo

Cairo, Illinois, is perfect for outdoor and adventure enthusiasts seeking scenic experiences. Visitors can explore a variety of attractions, including national parks, wildlife reserves, and historic forts. Whether you're interested in culture or simply enjoying nature, Cairo offers numerous points of interest that promise an enriching vacation for all types of travelers.

  • Columbus-Belmont State Park: Located 27km from Cairo, this park offers stunning views of the Mississippi River and opportunities for outdoor adventures like hiking and picnicking. The park features historical markers that highlight its role in the Civil War, providing a blend of nature and history.
  • Ballard Wildlife Management Area: Just 8km away, this area is a haven for wildlife enthusiasts. With its rich history and budget-friendly access, you can explore trails while observing various bird species and other wildlife in their natural habitat.
  • Fort Defiance State Park: Situated within Cairo, this historic site showcases the confluence of the Ohio and Mississippi Rivers. It offers cultural insights through its historical significance and scenic viewpoints, making it a great place for relaxation and exploration.

Best time to go to Cairo

The best time to visit Cairo can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Cairo falls in July, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Cairo falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January35.2°F (1.8°C)Light RainMostly SunnyModerately LowSlightly Low
February38.5°F (3.6°C)Light RainMostly SunnyModerately LowAverage
March48.7°F (9.3°C)Light RainMostly SunnyModerately HighSlightly High
April57.7°F (14.3°C)Light RainMostly SunnyModerately HighSlightly High
May67.5°F (19.7°C)Light RainMostly SunnyAverageSlightly High
June76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
July79.0°F (26.1°C)Light RainMostly SunnyAverageAverage
August77.2°F (25.1°C)Light RainMostly SunnyModerately HighAverage
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
November47.8°F (8.8°C)Light RainMostly SunnyModerately LowSlightly Low
December40.6°F (4.8°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Cairo

Traveling to Cairo, Illinois, is accessible via several nearby airports. Cape Girardeau Municipal Airport (CGI) is located 42km away and offers convenient hotels like Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown, both around 10km from the airport. Veterans Airport of Southern Illinois (MWA) is 84km away, with nearby accommodations such as Drury Inn & Suites Marion, just 3km from the airport. For the closest option, Cairo Regional Airport (CIR) is only 8km away, featuring hotels like Quality Inn Cairo I-57, just 3km from the airport, making it easy for tourists to find suitable lodging.

Frequently asked questions

Where is the best place for a stay in Cairo?
Based on our traveler data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your trip to the area are Super 8 by Wyndham Charleston/Sikeston East MO and The Riverstone Hotel Charleston-Sikeston. See all available top hotels, or vacation rentals in Cairo.
If I need to cancel my hotel reservation in Cairo, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.
Where can I learn more about changing or cancelling my trip to Cairo?
For more information about updating your trip to Cairo or cancelling it, head over to our customer service page.
Where is the best hotel to stay close to Fort Defiance?
Quality Inn Cairo I-57 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.9 mi (7.8 km) from Fort Defiance. Other good options around the area include Victorian Splendor in So. Illinois: wallmanor.com and Eagle Inn Charleston.
What's the best hotel for staying near Barkley Regional Airport (PAH)?
Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.
What is staying in Cairo like?
Visitors can enjoy all that Cairo has to offer including the restaurants, entertainment choices, and riverfront. This city also attracts tourists with its small-town vibe. There are 28 hotels and other accommodations in the surrounding area. Find out more about Cairo.
What should I see while I'm in Cairo?
The picturesque setting of Mississippi River and Ohio River Valley exemplify the area's natural beauty. Additionally, you might want to add Fort Defiance State Park to your itinerary. Check out what more to see and do in Expedia's Cairo guide.
What's the seasonal weather like in Cairo?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.

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