A sunset over a mountainous landscape with scattered clouds.

La Mesa 4 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on La Mesa 4 Star Hotels

Tonight
Oct 24 - Oct 25
Tomorrow
Oct 25 - Oct 26
Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Our top choices for La Mesa 4-star hotels

A balcony with wicker furniture overlooking a marina and a coastal cityscape.
A resort with a large swimming pool, lounge areas, and a marina in the background.
A marina with boats docked, a large white yacht, and a sunset in the background.
An outdoor dining area with tables and chairs arranged on a grassy lawn, overlooking a body of water with a sailboat in the distance.

1. Sheraton San Diego Resort

Sheraton San Diego Resort
Harbor Island
United States
James
NT$3,782
NT$5,996 total
includes taxes & fees
Nov 22 - Nov 23
Sheraton San Diego Resort
An aerial view of a resort with a central swimming pool, palm trees, and a view of the ocean and beach.
An outdoor dining area with tables and chairs, umbrellas, and string lights against a sunset backdrop.
A waterfront hotel with a dock, palm trees, and a view of the water.
A modern building with a curved roof, surrounded by lush tropical vegetation.

2. Paradise Point Resort & Spa

Paradise Point Resort & Spa
Mission Bay
Canada
Jesse
NT$7,786
NT$10,672 total
includes taxes & fees
Nov 8 - Nov 9
Paradise Point Resort & Spa
A hotel courtyard with outdoor seating, palm trees, and a view of the ocean at dusk.
A modern living room with a green sofa, a round glass table, and a flat-screen TV mounted on the wall.
A high-rise urban area with modern buildings, palm trees, and a clear sky.
A marina with multiple boats docked and tall buildings in the background.

3. Wyndham San Diego Bayside

Wyndham San Diego Bayside
Downtown San Diego
United States
Sarah
NT$4,952
NT$6,875 total
includes taxes & fees
Oct 27 - Oct 28
Wyndham San Diego Bayside
Poolside bar
A modern living room with a dining area, a flat-screen TV, a bar area, and a large window with a view of the city.
A dimly lit interior with a long bench seating area, pendant lighting, and a stage with curtains.
A Hard Rock Hotel with a prominent Hard Rock Cafe sign, a large marquee, and a modern building facade.

4. Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
Downtown San Diego
United States
Alexander
NT$5,053
NT$7,433 total
includes taxes & fees
Nov 22 - Nov 23
Hard Rock Hotel San Diego
An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.
A swimming pool with a visible water filtration system and a tiled edge.
A beach with clear skies, a rocky cliff, and a lighthouse in the distance.
A hotel room with a large bed, a chair, a nightstand, and a lamp.

5. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Kunta
NT$4,952
NT$6,620 total
includes taxes & fees
Nov 13 - Nov 14
Embassy Suites by Hilton San Diego La Jolla
A swimming pool with a person holding a glass, surrounded by palm trees and a building with a unique roof design.
A spacious lobby with a grand chandelier, wooden architecture, and a green upholstered seating area.
Bar (on property)
A large, multi-story hotel with a central courtyard, surrounded by a beach and ocean view.

6. Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton
Historic Downtown Coronado
United States
Marianne
NT$16,521
NT$20,148 total
includes taxes & fees
Nov 8 - Nov 9
Hotel del Coronado, Curio Collection by Hilton
A room with a blue sofa, a small wooden side table with a vase of flowers, and a view of a body of water and distant buildings.
A spacious hotel dining area with multiple tables and chairs, large windows, and a view of the outdoors.
Room
A bar area with a long counter, bar stools, and a view of the city through large windows.

7. Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
Downtown San Diego
United States
Sarah
NT$5,779
NT$8,477 total
includes taxes & fees
Nov 24 - Nov 25
Manchester Grand Hyatt San Diego
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A checkered floor with round tables and chairs, a patterned ceiling, and large windows.
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A dimly lit room with patterned walls, a wooden table, and a chair.

8. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
United States
Stacey
NT$8,886
NT$10,214 total
includes taxes & fees
Nov 3 - Nov 4
Lafayette Hotel & Club
A resort pool with a lazy river, palm trees, and a view of the ocean.
A hotel entrance with a covered walkway, palm trees, and a modern building in the background.
An aerial view of a marina with numerous boats docked, a bridge connecting to the mainland, and surrounding greenery.
A balcony with two chairs and a small table, overlooking a marina with numerous boats and a cityscape in the background.

9. Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
Mission Bay
United States
Megan
NT$6,455
NT$9,145 total
includes taxes & fees
Nov 19 - Nov 20
Hyatt Regency Mission Bay Spa and Marina
An aerial view of a resort with multiple swimming pools, lounge areas, and palm trees.
A marina with numerous boats docked, a large ship in the background, and a modern building with balconies.
A bar area with a long counter, multiple stools, and hanging wicker lamps.
A modern hotel with a prominent circular tower and a glass facade.

10. Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
Downtown San Diego
United States
Thomas Roy
NT$9,291
NT$12,313 total
includes taxes & fees
Nov 24 - Nov 25
Marriott Marquis San Diego Marina
A Marriott hotel with multiple floors, balconies, and a cityscape in the background.
A spacious lobby with a central seating area, a reception desk, and a modern ceiling design.
A modern lounge area with multiple seating options, including sofas and chairs, arranged around tables.
A cocktail on a balcony with a cityscape view.

11. San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter
Downtown San Diego
United States
Carolina
NT$5,237
NT$6,072 total
includes taxes & fees
Oct 25 - Oct 26
San Diego Marriott Gaslamp Quarter
A poolside view with a lounge chair, a towel, a tray with a drink and a coconut, and a pool with palm trees in the background.
A spacious lobby with a high ceiling, large windows, and a view of palm trees.
A coastal hotel with multiple buildings, a marina with boats, and a beach area.
A modern dining area with a glass table, candles, and wicker chairs.

12. San Diego Mission Bay Resort

San Diego Mission Bay Resort
Mission Bay
United States
Mary
NT$7,466
NT$10,306 total
includes taxes & fees
Oct 28 - Oct 29
San Diego Mission Bay Resort
A rooftop lounge area with outdoor seating, a pool, and umbrellas.
A spacious lobby with a high ceiling, a large sectional sofa, multiple seating areas, and a modern chandelier.
A modern bar area with a curved counter, multiple bar stools, and a large window offering a view of the cityscape.
A spacious lobby with large windows, curved ceiling, and comfortable seating areas.

13. Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
Downtown San Diego
United States
James
NT$5,296
NT$7,614 total
includes taxes & fees
Nov 22 - Nov 23
Omni San Diego Hotel at the Ballpark
A hotel entrance with a modern building, a central illuminated sculpture, and a landscaped area with plants.
A modern living room with a sofa, coffee table, and TV. There is a staircase leading to another level, and a large window with curtains.
A large building with a central dome and a reflection in the water.
A hotel room with a balcony, a TV mounted on the wall, a round wooden table with two white chairs, and a grey sofa.

14. The Westin San Diego Gaslamp Quarter

The Westin San Diego Gaslamp Quarter
Downtown San Diego
United States
Gregory
NT$6,814
NT$8,851 total
includes taxes & fees
Oct 25 - Oct 26
The Westin San Diego Gaslamp Quarter
A modern lobby with a sofa set, armchairs, a small table, and a green wall with plants.
A cozy outdoor seating area with wicker furniture, a fire pit, and a bar with a city view.
A bar area with stools, a sofa set, a fire pit, and a television mounted on the wall.
A spacious living area with a large sectional sofa, a coffee table, and a seating area with armchairs. There is a bar area in the background with stools and a television.

15. Hilton San Diego Gaslamp Quarter

Hilton San Diego Gaslamp Quarter
Downtown San Diego
United States
Cliff
NT$5,347
NT$7,711 total
includes taxes & fees
Nov 22 - Nov 23
Hilton San Diego Gaslamp Quarter
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A modern interior with wooden panel ceilings, patterned seating, and a central bar area.
A swimming pool with blue lounge chairs and umbrellas, surrounded by a building with balconies.
A pathway leading to a building labeled "LEGACY Hotel."

16. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
United States
christopher
NT$5,281
NT$6,071 total
includes taxes & fees
Nov 8 - Nov 9
Legacy Resort Hotel & Spa
A modern hotel with a courtyard featuring outdoor seating, a chess table, and a well-maintained lawn.
A snack display with a variety of packaged foods and a refrigerated section labeled 'SNACKS.'
A modern kitchen with a 'Hampton Waffle' sign, a 'Happy Breakfast Starts Here' sign, and a view into the dining area.
A hotel room with two beds, a desk, a chair, and a large window with curtains.

17. Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
Point Loma
United States
Evelin
NT$4,952
NT$5,692 total
includes taxes & fees
Nov 3 - Nov 4
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
A spacious lobby with a modern staircase, comfortable seating, and large windows offering natural light.
An outdoor wedding venue with rows of chairs, floral centerpieces, and string lights.
An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.
A modern interior with a seating area featuring round tables and chairs, a large mirror, and a unique ceiling light fixture.

18. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
Mexico
LUIS
NT$4,244
NT$4,878 total
includes taxes & fees
Nov 11 - Nov 12
Hilton San Diego Mission Valley
An outdoor lounge area with seating, a fire feature, and a pool in the background.
A modern restaurant with multiple seating areas, including booths and tables. There are hanging lights and a variety of plants.
A stone wall with a neon sign that reads "Tom & Jerry."
A hotel with a large pool surrounded by lounge chairs and umbrellas, palm trees, and a well-lit building facade.

19. Town and Country San Diego

Town and Country San Diego
Mission Valley
United States
Nelly
NT$5,193
NT$7,095 total
includes taxes & fees
Nov 24 - Nov 25
Town and Country San Diego
A swimming pool with palm trees and a mountain in the background.
A modern bar area with a long counter, multiple stools, and a variety of bottles on shelves.
A modern lounge area with leather seating, a central fire feature, and geometric patterned railings.
A modern lounge area with dark-toned seating, a central coffee table, and a stone accent wall.

20. Sycuan Casino Resort

Sycuan Casino Resort
El Cajon
United States
Sarah
NT$3,214
NT$3,927 total
includes taxes & fees
Nov 16 - Nov 17
Sycuan Casino Resort
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in La Mesa.
Pendry San Diego

Pendry San Diego

550 J Street San Diego CA
NT$9,602
NT$12,918 total
Nov 24 - Nov 25
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
Pendry San Diego
The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego

326 Broadway San Diego CA
NT$7,724
NT$8,968 total
Nov 8 - Nov 9
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
The US Grant, a Luxury Collection Hotel, San Diego
L'Auberge Del Mar

L'Auberge Del Mar

1540 Camino Del Mar Del Mar CA
NT$12,336
NT$16,382 total
Oct 25 - Oct 26
includes taxes & fees
8.8/10 Excellent! (887 reviews)
L'Auberge Del Mar
Still don't see what you're looking for?
See all properties in La Mesa.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

See all hotels in La Mesa
A sunset over a mountainous landscape with scattered clouds.

Top La Mesa Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"Centrally located"
Luis Jose Delmonte 4-night trip
Posted 3 hours ago
Wyndham San Diego Bayside
Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

8/10 Good
"The Views offfered extraordinary experiences in comfort and location. Situated across from an HVAC station emitting near-constant turbine-like whining noises 24/7, I recommend this place to travelers with some hearing impairment for maximum comfort at night. I also struggled with bath and bathroom access in a fight with swing doors that block access to sink and shower enclosure creating a constant tangle upon entry and exit. Still, I look forward to my next visit(s)."
Erik 5-night trip
Posted 23 hours ago
Hotel del Coronado, Curio Collection by Hilton

Frequently asked questions

What are the best 4-star hotels in La Mesa?
San Diego Marriott Mission Valley is a 4-star hotel in La Mesa that's popular among Expedia guests. A swimming pool and concierge services are some of its many amenities. Travelers also recommend Sheraton Mission Valley San Diego Hotel. From concierge services to a spa tub, it comes with conveniences that cater to every aspect of your relaxation and enjoyment.
How much does it cost to stay in a 4-star hotel in La Mesa?
With Expedia's search and sort filters, landing a great deal on a 4-star hotel in La Mesa just got simpler. Start by keying in your chosen arrival date and length of your break. Then list the results by price and choose a hotel that best fits your style and budget.
  • Search for the lowest price from NT$8,968
What's the difference between 5-star and 4-star hotels in La Mesa?
Treat yourself to luxury living during your La Mesa vacation by choosing a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually packed with amenities, including complimentary bathrobes, large beds and more. A 5-star hotel will go the extra mile to make your stay an even more lavish and special one. 24-hour concierge assistance, elegant décor and world-class dining are only the start of the superior services and conveniences you'll likely be able to enjoy.

Explore a world of travel with Expedia