A red train on tracks, palm trees, and modern buildings.

Central San Diego 4 Stars Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Central San Diego 4 Star Hotels

Tonight
Aug 6 - Aug 7
Tomorrow
Aug 7 - Aug 8
This weekend
Aug 7 - Aug 9
Next weekend
Aug 14 - Aug 16

Our top choices for Central San Diego 4-star hotels

1. San Diego Marriott La Jolla

San Diego Marriott La Jolla
University City
United States
Sirlei
NT$5,941
NT$6,834 total
includes taxes & fees
Sep 3 - Sep 4
San Diego Marriott La Jolla

2. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
Mission Valley
United States
Victor
NT$5,136
NT$5,904 total
includes taxes & fees
Aug 31 - Sep 1
San Diego Marriott Mission Valley

3. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
United States
Jorgen
NT$8,030
NT$9,230 total
includes taxes & fees
Sep 7 - Sep 8
Lafayette Hotel & Club

4. Town and Country San Diego

Town and Country San Diego
Mission Valley
United States
Debora
NT$5,739
NT$7,711 total
includes taxes & fees
Aug 31 - Sep 1
Town and Country San Diego

5. DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
Mission Valley
United States
Benedict
NT$4,477
NT$5,146 total
includes taxes & fees
Aug 13 - Aug 14
DoubleTree by Hilton Hotel San Diego - Mission Valley

6. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
United States
T'Andra
NT$4,469
NT$5,137 total
includes taxes & fees
Aug 25 - Aug 26
Hilton San Diego Mission Valley

7. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Tamisha
NT$5,801
NT$7,588 total
includes taxes & fees
Aug 9 - Aug 10
Embassy Suites by Hilton San Diego La Jolla

8. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
United States
Shakundala
NT$6,499
NT$7,470 total
includes taxes & fees
Aug 30 - Aug 31
Legacy Resort Hotel & Spa

9. Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
Mission Valley
United States
Robert
NT$6,643
NT$7,636 total
includes taxes & fees
Aug 28 - Aug 29
Sheraton Mission Valley San Diego Hotel

10. Hyatt Regency La Jolla

Hyatt Regency La Jolla
University City
United States
Rachel
NT$6,848
NT$9,062 total
includes taxes & fees
Aug 30 - Aug 31
Hyatt Regency La Jolla

11. DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
Mission Valley
United States
Rachel
NT$4,212
NT$4,841 total
includes taxes & fees
Aug 24 - Aug 25
DoubleTree by Hilton San Diego - Hotel Circle

12. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
Middletown
United States
omokayode
NT$4,213
NT$5,847 total
includes taxes & fees
Aug 31 - Sep 1
City24 Hotel Little Italy Mission Hills

13. Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
Mission Valley
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Central San Diego

A must-see zoo, seaside views, and top sights from San Diego Zoo to Snapdragon Stadium—discover Central San Diego, a historic destination also famous for its sports teams.

See all hotels in Central San Diego
A red train on tracks, palm trees, and modern buildings.

Top Central San Diego Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.
  • Search for the lowest price
What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.

Explore a world of travel with Expedia