Southwest Minnesota Luxury Vacations 2026

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Top Luxury Southwest Minnesota Hotels

AmericInn by Wyndham Blue Earth

1495 Domes Dr Blue Earth MN

1 hour drive from Mayo Clinic Health System Event Center

Go for a luxurious stay at AmericInn by Wyndham Blue Earth, where you can enjoy amenities like 24-hour room service, premium channels, and more.

7.8/10 Good! (518 reviews)

"The usual clean room and convenient location. Bob"

Reviewed on 2026/9/29

Super 8 by Wyndham Jackson MN

2025 Highway 71 N Jackson MN

3 hours drive from Mayo Clinic Health System Event Center

Indulge yourself with classy lodging at Super 8 by Wyndham Jackson MN, where you'll enjoy amenities like premium channels and more.

Days Inn by Wyndham Mankato

1285 Range St Mankato MN

4 min drive from Mayo Clinic Health System Event Center

Discover luxurious lodging at Days Inn by Wyndham Mankato, where you can enjoy amenities like premium channels, flat-screen TVs, and more. Deluxe amenities at ...

6.6/10 (896 reviews)

"Really terrible staff at reception"

Reviewed on 2026/9/29

See all 978 properties in Southwest Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.