Cheap flights from San Francisco to Knoxville (SFO to TYS)

A tower with a spherical top, fireworks in the sky, and a cityscape with buildings and a tented area.

Popular airlines from San Francisco Intl. Airport (SFO) to McGhee Tyson Airport (TYS)

Be in the know
Get alerts if flight prices drop or rise*
Book smarter
Save up to 45% on select hotels after you book a flight*
Earn twice
Earn your airline miles on top of our rewards
Sign in

Travel information

Origin airport	San Francisco Intl. Airport
Destination airport	McGhee Tyson Airport
Distance	3,404 km away
Airlines serving	Alaska Airlines, American Airlines, United, Southwest Airlines, Delta
Popular airline	Alaska Airlines

Explore a world of travel with Expedia

Flights from Rutland (RUT) to Knoxville (TYS)
Standard Link for Flights from Rutland (RUT) to Knoxville (TYS)
Flights from Grand Forks (GFK) to Knoxville (TYS)
Standard Link for Flights from Grand Forks (GFK) to Knoxville (TYS)
Flights from Kayenta (MVM) to Knoxville (TYS)
Standard Link for Flights from Kayenta (MVM) to Knoxville (TYS)
Flights from Samos (SMI) to Knoxville (TYS)
Standard Link for Flights from Samos (SMI) to Knoxville (TYS)
Flights from Beirut (BEY) to Knoxville (TYS)
Standard Link for Flights from Beirut (BEY) to Knoxville (TYS)
Flights from Blagoveschensk (BQS) to Knoxville (TYS)
Standard Link for Flights from Blagoveschensk (BQS) to Knoxville (TYS)
Flights from Sault Ste. Marie (SSM) to Knoxville (TYS)
Standard Link for Flights from Sault Ste. Marie (SSM) to Knoxville (TYS)
Flights from Idaho Falls (IDA) to Knoxville (TYS)
Standard Link for Flights from Idaho Falls (IDA) to Knoxville (TYS)
Flights from North Bay (YYB) to Knoxville (TYS)
Standard Link for Flights from North Bay (YYB) to Knoxville (TYS)
Flights from Cancun (CUN) to Knoxville (TYS)
Standard Link for Flights from Cancun (CUN) to Knoxville (TYS)
Flights from Riohacha (RCH) to Knoxville (TYS)
Standard Link for Flights from Riohacha (RCH) to Knoxville (TYS)
Flights from Raleigh (RDU) to Knoxville (TYS)
Standard Link for Flights from Raleigh (RDU) to Knoxville (TYS)
Flights from Whitehorse (YXY) to Knoxville (TYS)
Standard Link for Flights from Whitehorse (YXY) to Knoxville (TYS)
Flights from Branson (BKG) to Knoxville (TYS)
Standard Link for Flights from Branson (BKG) to Knoxville (TYS)
Flights from Managua (MGA) to Knoxville (TYS)
Standard Link for Flights from Managua (MGA) to Knoxville (TYS)
Flights from Walland
Standard Link for Flights from Walland
Flights from Guangzhou (CAN) to Knoxville (TYS)
Standard Link for Flights from Guangzhou (CAN) to Knoxville (TYS)
Flights from Bird Island (BDI) to Knoxville (TYS)
Standard Link for Flights from Bird Island (BDI) to Knoxville (TYS)
Flights from Jackson (JAN) to Knoxville (TYS)
Standard Link for Flights from Jackson (JAN) to Knoxville (TYS)
Flights from French Lick (FRH) to Knoxville (TYS)
Standard Link for Flights from French Lick (FRH) to Knoxville (TYS)
Flights from Corpus Christi (CRP) to Knoxville (TYS)
Standard Link for Flights from Corpus Christi (CRP) to Knoxville (TYS)
Flights from Arad (ARW) to Knoxville (TYS)
Standard Link for Flights from Arad (ARW) to Knoxville (TYS)
Flights from Huntsville (HSV) to Knoxville (TYS)
Standard Link for Flights from Huntsville (HSV) to Knoxville (TYS)
Flights from Trinidad (TDD) to Knoxville (TYS)
Standard Link for Flights from Trinidad (TDD) to Knoxville (TYS)
Flights from Berlin (BER) to Knoxville (TYS)
Standard Link for Flights from Berlin (BER) to Knoxville (TYS)
Flights from Jackson Hole (JAC) to Knoxville (TYS)
Standard Link for Flights from Jackson Hole (JAC) to Knoxville (TYS)
Flights from New York (NYC) to Knoxville (TYS)
Standard Link for Flights from New York (NYC) to Knoxville (TYS)
Flights from Shakiso (SKR) to Knoxville (TYS)
Standard Link for Flights from Shakiso (SKR) to Knoxville (TYS)
Flights from Chongqing (CKG) to Knoxville (TYS)
Standard Link for Flights from Chongqing (CKG) to Knoxville (TYS)
Flights from Altus (AXS) to Knoxville (TYS)
Standard Link for Flights from Altus (AXS) to Knoxville (TYS)
Flights from Seattle (SEA) to Knoxville (TYS)
Standard Link for Flights from Seattle (SEA) to Knoxville (TYS)

*Available to One Key members.

Cheap Flights from San Francisco (SFO) to Knoxville (TYS)

Popular airlines from San Francisco Intl. Airport (SFO) to McGhee Tyson Airport (TYS)

Be in the know

Book smarter

Earn twice

Travel information

Explore a world of travel with Expedia