Upstate South Carolina Romantic Vacations

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Top Romantic Upstate South Carolina Hotels

Greenville Marriott

Greenville Marriott

One Parkway E Greenville SC
  • 2 hours drive from Clemson University
Rekindle the romance with your special someone. Consider booking a getaway at this hotel where you're sure to love the premium mattresses and luxury bedding. ...
Greenville Marriott
Hotel Domestique

Hotel Domestique

10 Road of Vines Travelers Rest SC
  • 2 hours drive from Clemson University
Indulge in a romantic getaway at this boutique hotel, where you'll find spa services, in-room massages, and a garden. Couples will love the lobby fireplace and ...
9.8/10 Exceptional! (36 reviews)

Couples like: onsite spa services, bar, champagne service, romance packages available

Travelers say...
"SERVICIO Y ATENCION DE CALIDAD, LA COMIDA DEL RESTAURANTE MUY RICA. LIMPIEZA DE LAS HABITACIONES, INSTALACIONES, PISCINA EN GENERAL UN ESTABLECIMIENTO MUY REFINADO QUE TE HACEN SENTIR EN CASA. PRECIO VALOR EXCELENTE."

Reviewed on 2026/8/22

Hotel Domestique
See all 3,080 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.