Southern Minnesota Pet-friendly Vacations 2026

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Top Pet-friendly Southern Minnesota Hotels

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

4353 Canal Pl SE Rochester MN

11 min drive from Mayo Clinic

Make it a pet-friendly trip and bring along your four-legged friend. Dogs are welcome (fees apply) at this suburban hotel.

7.4/10 Good! (1,074 reviews)

"The employees are very helpful in every way possible"

Reviewed on 2026/10/1

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

26 min walk from Mayo Clinic

Dogs are welcome to join you (fees apply) for a pet-friendly getaway at this family-friendly, city-center motel.

7.8/10 Good! (1,026 reviews)

"A terrible place- We arrived in the evening. The guy that checked us in didn't seem friendly. We went out and ate supper after check in. When we got back, it was late. We should have checked the room better before we left to eat. The ceiling in the bathroom had a big bulge, and the bathrm exhaust ..."

Reviewed on 2026/9/30

Spark by Hilton Rochester South

4165 Maine Ave SE Rochester MN

10 min drive from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

See all 1,232 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.