Southern Minnesota Pet-friendly Vacations

Book a Pet-friendly Hotel + Flight or Car together to unlock savings

Photo by Howard Lower Photography
    deals illustration

    Better together

    Save up to NT$5,067 when you book a flight and hotel together*
    stays illustration

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    luggage illustration

    Rest easy

    Plan, book, and manage your trip all in one place

Top Pet-friendly Southern Minnesota Hotels

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
  • 11 min drive from Mayo Clinic
Make it a pet-friendly trip and bring along your four-legged friend. Dogs and cats are welcome (fees apply) at this suburban hotel.
7.2/10 Good! (1,013 reviews)
"Nice place. To stay"

Reviewed on 2025/7/9

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
Dogs are welcome to join you (fees apply) for a pet-friendly getaway at this family-friendly, city-center motel.
7.8/10 Good! (1,007 reviews)
"Older property but clean and close to Mayo Clinic with a free shuttle which was very appreciated."

Reviewed on 2025/7/8

Med City Inn & Suites - Mayo Clinic Area
Spark by Hilton Rochester South
Spark by Hilton Rochester South
3 out of 5
4165 Maine Ave SE, Rochester, MN
  • 10 min drive from Mayo Clinic
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (68 reviews)
"Very nice hotel for a great price"

Reviewed on 2025/7/8

Spark by Hilton Rochester South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.