Find hotels in Uptown Greenville, Greenville

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Our top choices for Uptown Greenville hotels

Hilton Garden INN Greenville University

Hilton Garden INN Greenville University
3.0 star property
Uptown Greenville
9.4 out of 10, Exceptional, (92)
"Great location. Rooftop bar and restaurant was nice and convenient."
United States
GEORGE
The price is NT$3,848
NT$4,348 total
includes taxes & fees
Dec 28 - Dec 29
Hilton Garden INN Greenville University

Country Inn & Suites by Radisson, Greenville, NC

Country Inn & Suites by Radisson, Greenville, NC
3.0 star property
6.7 km from Uptown Greenville
7.6 out of 10, Good, (820)
"Staff was very friendly and property was in a convenient location "
United States
Michele
The price is NT$2,949
NT$3,364 total
includes taxes & fees
Dec 25 - Dec 26
Country Inn & Suites by Radisson, Greenville, NC

Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG
3.0 star property
2.3 km from Uptown Greenville
9.4 out of 10, Exceptional, (241)
"I enjoyed my stay very clean and comfortable "
United States
LATONYA
The price is NT$3,150
NT$3,559 total
includes taxes & fees
Dec 28 - Dec 29
Staybridge Suites Greenville Medical Center by IHG

Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville
3.0 star property
2.4 km from Uptown Greenville
8.8 out of 10, Excellent, (466)
"Rooms are very nice, quiet "
United States
David
The price is NT$3,496
NT$3,950 total
includes taxes & fees
Dec 23 - Dec 24
Residence Inn by Marriott Greenville

Hilton Greenville

Hilton Greenville
4.0 star property
Convention District, 4.5 km from Uptown Greenville
8.8 out of 10, Excellent, (532)
"Hotel was very nice and clean. "
United States
Marcie
The price is NT$4,370
NT$4,938 total
includes taxes & fees
Jan 4 - 2026/1/5
Hilton Greenville

Courtyard Marriott Greenville

Courtyard Marriott Greenville
3.0 star property
Medical District, 2.8 km from Uptown Greenville
8.8 out of 10, Excellent, (881)
"Clean rooms, friendly staff and great location. Enjoyed our stay."
United States
Frederick
The price is NT$3,716
NT$4,200 total
includes taxes & fees
Dec 28 - Dec 29
Courtyard Marriott Greenville

Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Convention District, 4.3 km from Uptown Greenville
9.0 out of 10, Wonderful, (571)
"Great stay."
United States
Mario
The price is NT$3,738
NT$4,224 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn Greenville

Fairfield Inn & Suites by Marriott Greenville

Fairfield Inn & Suites by Marriott Greenville
2.5 star property
2.4 km from Uptown Greenville
8.6 out of 10, Excellent, (457)
"Convenient to Maynard children’s hospital. Friendly staff. Safe environment "
United States
DARLENE
The price is NT$3,716
NT$4,200 total
includes taxes & fees
Dec 20 - Dec 21
Fairfield Inn & Suites by Marriott Greenville

Candlewood Suites Greenville NC by IHG

Candlewood Suites Greenville NC by IHG
2.5 star property
4.7 km from Uptown Greenville
8.6 out of 10, Excellent, (586)
"I loved it will visit again "
United States
natalie
The price is NT$2,740
NT$3,096 total
includes taxes & fees
Dec 28 - Dec 29
Candlewood Suites Greenville NC by IHG

Little Inn on Main

Little Inn on Main
3.0 star property
29.7 km from Uptown Greenville
9.6 out of 10, Exceptional, (75)
"Love the hotel clean and comfortable great location "
United States
Elizabeth
Little Inn on Main

Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG
3.0 star property
Convention District, 4.3 km from Uptown Greenville
8.8 out of 10, Excellent, (1000)
"Nice clean room. Very friendly staff."
United States
Jennifer
The price is NT$3,496
NT$3,950 total
includes taxes & fees
Dec 23 - Dec 24
Holiday Inn Greenville by IHG

Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
2.3 km from Uptown Greenville
8.4 out of 10, Very Good, (966)
"Great location and breakfast menu "
United States
Angela
The price is NT$3,374
NT$3,813 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express Greenville by IHG

Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic
2.0 star property
2.5 km from Uptown Greenville
7.2 out of 10, Good, (1001)
"Staff is nice and friendly "
United States
Tonya
The price is NT$2,035
NT$2,299 total
includes taxes & fees
Dec 28 - Dec 29
Microtel Inn & Suites by Wyndham Greenville/University Medic

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
2.3 km from Uptown Greenville
6.6 out of 10, (581)
"Staff was nice, room was clean. Had a great experience."
United States
Lashonda
The price is NT$2,061
NT$2,329 total
includes taxes & fees
Dec 31 - 2026/1/1
Super 8 by Wyndham Greenville

Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC
3.0 star property
2.4 km from Uptown Greenville
9.4 out of 10, Exceptional, (306)
"Room was perfect. We really appreciate our stay. "
United States
Carol
The price is NT$3,633
NT$4,105 total
includes taxes & fees
Dec 26 - Dec 27
Homewood Suites By Hilton Greenville, NC

Quality Inn Greenville near University

Quality Inn Greenville near University
2.5 star property
2 km from Uptown Greenville
7.4 out of 10, Good, (1000)
"room clean, staff check in was efficient and helpful."
United States
Lynn
The price is NT$2,126
NT$2,402 total
includes taxes & fees
Dec 28 - Dec 29
Quality Inn Greenville near University

Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University
2.5 star property
4.9 km from Uptown Greenville
8.6 out of 10, Excellent, (393)
"I highly recomend and the staff is very friendly & helpful!"
United States
Carmen
The price is NT$3,505
NT$3,961 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn & Suites Greenville Near East Carolina University

Fairfield Inn and Suites by Marriott Washington

Fairfield Inn and Suites by Marriott Washington
2.5 star property
27.1 km from Uptown Greenville
9.4 out of 10, Exceptional, (627)
"Great staff, room was perfect!!"
United States
Teresa G
The price is NT$3,716
NT$4,190 total
includes taxes & fees
Dec 22 - Dec 23
Fairfield Inn and Suites by Marriott Washington

Red Roof Inn Greenville, NC

Red Roof Inn Greenville, NC
2.0 star property
3.4 km from Uptown Greenville
4.8 out of 10, (259)
"It was great for the price. Our room and bathroom were clean. Very close to tailgate field. Short Uber drive. We felt safe. "
United States
Stacy
The price is NT$2,008
NT$2,269 total
includes taxes & fees
Dec 22 - Dec 23
Red Roof Inn Greenville, NC

Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville
2.5 star property
3.9 km from Uptown Greenville
9.0 out of 10, Wonderful, (1003)
"I missed breakfast but i have stayed here before and it was good. "
United States
Randy
The price is NT$3,151
NT$3,560 total
includes taxes & fees
Dec 28 - Dec 29
Best Western Plus Suites-Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Uptown Greenville

Find the best Uptown Greenville areas and neighborhoods for the activities you enjoy most.

Medical District

While there might not be top attractions in Medical District, you can explore the larger area and discover places like Arlington Crossing and North Pines.

Westhaven

While Westhaven isn't home to many top sights, 11 Galleria and Arlington Crossing are some notable places to visit nearby.

College View Historic District

When in College View Historic District, you can plan a visit to Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area.

Greenville Heights

When in Greenville Heights, you can plan a visit to North Pines and Town Common, some noteworthy sights in the nearby area.

Top Uptown Greenville Hotel Reviews

Frequently asked questions

What is Uptown Greenville like?
Travelers will be sure to find plenty to entertain them in Greenville's Uptown Greenville neighborhood. Are you looking for Uptown Greenville travel tips? Be sure to check out Town Common and Greenville Museum of Art while you're in the neighborhood.
What's the best accommodation in Uptown Greenville?
Based on Expedia customer reviews, Hilton Garden INN Greenville University is the highest ranked property in Uptown Greenville. This hotel offers a restaurant and a 24-hour fitness center.
If I need to cancel my hotel reservation in Uptown Greenville, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the top deals on offer in Uptown Greenville.
Where can I learn more about changing or cancelling my trip to Uptown Greenville?
For more details about updating your trip to Uptown Greenville or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Greenville neighborhood?
A few attractions you might want to check out while you're in Uptown Greenville are Town Common and Greenville Museum of Art. Shepherd Memorial Library - Carver Branch and North Pines are also worth a visit when you're out sightseeing in Greenville.

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