Midtown, MO
St. Louis





Popular places to visit

St. Louis University
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theater scene.

Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's acclaimed theater scene or attend a baseball game.

St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Midtown Hotel Deals

Element St. Louis Midtown
The breakfast was lacking, parking was expensive and a pain (although the valet were the nicest staff), the pool was cold, our room was missing condition and they never brought us soap, they repeatedly forgot our towels after cleaning, our safe and phone were broken and never replaced or fixed after ...
Reviewed on 2026/4/7

Residence Inn by Marriott St Louis Downtown
Staff was great. The hotel could use work. One of the t.v.’s in the room didn’t work. Door stuck in bathroom. Pool area not stocked with towels and could be cleaner. Breakfast was good.
Reviewed on 2026/4/8

Clayton Plaza Hotel & Extended Stay
Room was clean and good size. Decor was a little dated but room did seem to have been recently renovated. Bathroom was updated and higher end with a digital shower. Several restaurants within walking distance. It is located in business district with a park about ten minute walk from the hotel.
Reviewed on 2026/4/9

Drury Plaza Hotel St. Louis at the Arch
Nice clean room
Reviewed on 2026/4/9

Pear Tree Inn St. Louis Near Union Station
TV lost signal for hours the 2 nights we stayed during the ncaa basketball tournament. Was not happy at all!
Reviewed on 2026/4/9

21C Museum Hotel St Louis
Beautiful, repurposed hotel with gorgeous lobby, amazing art museum, top-notch pool and spa facilities, central location, and very comfortable and compact room. We will definitely stay here again if we find another great deal!
Reviewed on 2026/4/9
Other neighborhoods around Midtown

The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.

The Grove
The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

Shaw
While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
