Photo by Bill Dillard
Find Cheap Hotels in Southeast Missouri, MO
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Southeast Missouri Cheap Hotels
Top Southeast Missouri Cheap Hotels

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
8.4 out of 10, Very Good, (714)
The price is NT$2,056
NT$2,343 total
includes taxes & fees
Dec 1 - Dec 2

Pear Tree Inn Cape Girardeau West
Cape Girardeau
9.0 out of 10, Wonderful, (1007)
The price is NT$2,197
NT$2,479 total
includes taxes & fees
Dec 4 - Dec 5

Microtel Inn & Suites by Wyndham Sainte Genevieve
Ste Genevieve
8.8 out of 10, Excellent, (610)
The price is NT$2,135
NT$2,382 total
includes taxes & fees
Dec 7 - Dec 8

New Orleans Inn Portageville
Portageville
8.0 out of 10, Very Good, (723)

Quality Inn Farmington
Farmington
7.6 out of 10, Good, (857)
The price is NT$1,601
NT$1,912 total
includes taxes & fees
Dec 14 - Dec 15

Motel 6 Poplar Bluff, MO
Poplar Bluff
7.8 out of 10, Good, (1009)
The price is NT$2,386
NT$2,516 total
includes taxes & fees
Dec 6 - Dec 7

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
The price is NT$2,825
NT$3,187 total
includes taxes & fees
Dec 7 - Dec 8

Pear Tree Inn Cape Girardeau Near the Medical Center
Cape Girardeau
9.0 out of 10, Wonderful, (1005)
The price is NT$2,197
NT$2,479 total
includes taxes & fees
Dec 4 - Dec 5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau West
10/10 Excellent
Explore a world of travel with Expedia
Find More Hotels near Southeast Missouri
More Hotel Options in Southeast Missouri
- Adults Only Resorts & Hotels in Southeast Missouri
- Adventure Hotels in Southeast Missouri
- Business Hotels in Southeast Missouri
- Casinos in Southeast Missouri
- Family Hotels in Southeast Missouri
- Golf Hotels in Southeast Missouri
- Historic Hotels in Southeast Missouri
- Hotel Wedding Venues in Southeast Missouri
- Hotel with a Concierge in Southeast Missouri
- Hotels with Bars in Southeast Missouri
- Hotels with Free Parking in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotels with WiFi in Southeast Missouri
- Hotels with a Pool in Southeast Missouri
- Hotels with an Indoor Pool in Southeast Missouri
- Hotels with smoking rooms in Southeast Missouri
- Luxury Hotels in Southeast Missouri
- Pet-friendly Hotels in Southeast Missouri
- Resorts & Hotels with Spas in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Shopping Hotels in Southeast Missouri
- Ski Hotels in Southeast Missouri
- Winery Hotels in Southeast Missouri
More Accommodation Types in Southeast Missouri
- Condo Rentals in Missouri
- Apartments in Missouri
- Cottages in Missouri
- Vacation Homes in Missouri
- Motels in Missouri
- Cabin Rentals in Missouri
- B&B in Missouri
- Aparthotels in Missouri
- Guest Houses in Missouri
- Lodges in Missouri
- Resorts in Missouri
- Villas in Missouri
- Inns in Missouri
- RV Parks in Missouri
- Condo Resorts in Missouri
- Hostels in Missouri
- Chalets in Missouri
- Residences in Missouri
Hotels near popular Southeast Missouri Attractions
- Hotels near Mark Twain National Forest
- Hotels near Elephant Rocks State Park
- Hotels near Southeast Missouri State University
- Hotels near Johnson's Shut-ins State Park
- Hotels near Ozark National Scenic Riverways
- Hotels near Century Casino Caruthersville
- Hotels near Current River
- Hotels near Isle Casino Cape Girardeau
- Hotels near Lake Wappapello
- Hotels near Taum Sauk Mountain State Park
Southeast Missouri Hotels by Star Rating
Explore more hotels
- Courtyard by Marriott Cape Girardeau Downtown
- Fairfield Inn & Suites by Marriott Poplar Bluff
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Drury Inn & Suites Sikeston, MO
- Drury Inn & Suites Jackson MO
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Drury Inn & Suites Cape Girardeau
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Candlewood Suites Cape Girardeau by IHG
- Drury Inn & Suites Poplar Bluff
- Super 8 by Wyndham Farmington
- Tru By Hilton Cape Girardeau
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Hampton Inn Poplar Bluff
- Best Western Plus Sikeston
- Hampton Inn Cape Girardeau I 55 East
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Drury Inn & Suites Hayti Caruthersville
- Quality Inn
More ways to book
Expedia's Latest Trends
Hotels
General
- Visit Bay Area
- Visit Cape Cod
- Visit Kauai
- Visit Flat River
- Visit Upstate New York
- Visit Oregon Coast
- Visit North Central Texas
- Visit Southeast Florida
- Visit Hawaii Island
- Visit Fire Island
- Visit Puget Sound
- Visit Long Island
- Visit Napa Valley
- Visit Sonoma Valley
- Visit Oahu
- Visit Northeast Georgia
- Visit Nantucket Island
- Visit North Coast California
- Visit Catalina Island
- Visit Finger Lakes Region
- Visit Outer Banks





































