The Best Hotels Closest to South Texas Medical Center in San Antonio for 2026

A modern medical building with reflective glass windows and a clear sky.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for South Texas Medical Center hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

An indoor swimming pool with multiple lanes, safety signs, and a view of the outside through large windows.

A hotel room with two beds, a TV, a desk with a lamp, and a dresser.

A modern lobby with a grey sofa, blue armchairs, and a stone accent wall.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Medical Center District, 2.9 km from South Texas Medical Center

Alba

NT$2,867

NT$3,389 total

includes taxes & fees

Oct 12 - Oct 13

A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

A modern cafe with wooden furniture, white tables, and a brick wall.

A swimming pool with a wooden ceiling, lounge chairs, and a view of trees and a building.

A Fairfield by Marriott Inn & Suites building with a modern design, featuring a prominent entrance with a covered walkway and a parking lot in front.

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Medical Center District, 1 km from South Texas Medical Center

Tiffany

NT$2,755

NT$3,217 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

A hotel entrance with a covered walkway, a wet driveway, and a tree in the foreground.

A modern hotel lobby with a mix of seating arrangements, including round tables and sofas, and a bar area with a high counter.

A hotel room with a large bed, a desk, and a chair.

3. Courtyard by Marriott Medical Center San Antonio

Medical Center District, 1.3 km from South Texas Medical Center

Erik

NT$3,126

NT$3,695 total

includes taxes & fees

Oct 12 - Oct 13

A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

A gym with multiple cardio machines, including treadmills and elliptical trainers, arranged in a spacious room with a carpeted floor and neutral-colored walls.

A hotel lobby with a reception desk, seating area, and a chandelier.

A hotel with a red-roofed entrance, multiple floors, and a visible flag.

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District, 2.4 km from South Texas Medical Center

Maria

NT$2,829

NT$3,344 total

includes taxes & fees

Oct 6 - Oct 7

A hotel pool area with lounge chairs and a building with large windows in the background.

A hotel lobby with a seating area, a large potted plant, a decorative wall, and a vintage car display.

A large banquet hall with round tables, chairs, and chandeliers.

5. The Westin San Antonio North

3.2 km from South Texas Medical Center

Barbara

NT$2,979

NT$3,571 total

includes taxes & fees

Oct 29 - Oct 30

A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

A hotel room with a bed, two bedside tables with lamps, a desk with a telephone, a mirror, and a door leading to another room.

A hotel entrance with an Atria Inn & Suites sign, a Classic Collins store, and a clear sky.

A hotel room with a sofa, a desk, a chair, a bed, and a mirror.

6. Atria Inn & Suites

Medical Center District, 2.2 km from South Texas Medical Center

Jose Rolando

NT$1,840

NT$2,148 total

includes taxes & fees

Oct 6 - Oct 7

A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

A clean, modern reception area with a large number '6' sign, a poster advertising a direct book service, and a view of the outside through a window.

A stone facade with a 'welcome' sign, a blue door, and a parking sign.

A laundry facility with multiple washing machines, a drying rack, and instructional posters on the wall.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Medical Center District, 2.7 km from South Texas Medical Center

Ruben

NT$1,524

NT$1,780 total

includes taxes & fees

Oct 9 - Oct 10

A modern kitchen with a large window, wooden counter, and two bar stools.

A Park Inn hotel with a brick facade, multiple parking spaces, and a clear sky.

A compact kitchenette with a built-in microwave, a black refrigerator, and a wooden countertop.

A reception desk with a modern design, featuring a white counter and dark cabinets. There are three pendant lights above the desk, and a large window with a view of greenery outside.

8. Park Inn by Radisson, Medical Center

Medical Center District, 1 km from South Texas Medical Center

Joanne

NT$2,139

NT$2,498 total

includes taxes & fees

Oct 26 - Oct 27

A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

A hotel reception area with a glass door entrance, a reception desk, and a wall-mounted sign for the OYO hotel.

A hotel room with two beds, a television, a desk with a computer, and a door.

A room with a table and chairs, a clock, and framed pictures on the wall.

9. OYO Inn & Suites Medical Center San Antonio

Medical Center District, 3.1 km from South Texas Medical Center

Melanie

NT$2,063

NT$2,615 total

includes taxes & fees

Oct 19 - Oct 20

A reception area with a glass door entrance, a reception desk, and a wall-mounted fire extinguisher.

A small, modern room with a wooden dining table, a mirror, a TV, and a small kitchenette.

A small, modern room with two brown leather sofas, a black cabinet, and a window with blinds.

A hotel room with a bed, bedside table, desk, chair, TV, and a wardrobe.

10. Motel 6 San Antonio, TX - Fiesta Trails

2.9 km from South Texas Medical Center

Alexis

NT$1,433

NT$1,674 total

includes taxes & fees

Oct 6 - Oct 7

A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

A building with a red roof and a sign reading "Flex Studios."

A bathroom with a granite countertop sink, a mirror, a shower with a glass door, and a toilet.

A building with a yellow facade and a sign reading "Flex Studios."

11. Flex Studios

Medical Center District, 2.7 km from South Texas Medical Center

Jasper

NT$1,402

NT$1,657 total

includes taxes & fees

Oct 6 - Oct 7

A modern bedroom with a large bed, bedside tables, a desk, and a chair.

A swimming pool with a stone wall and a 'No Diving' sign, surrounded by a fence and a building with a stone facade.

A hotel reception area with a large number '6' sign, a poster advertising direct booking, and a view of the outside through a window.

12. Motel 6 San Antonio, TX - Northwest Medical Center

Medical Center District, 2.8 km from South Texas Medical Center

Brian

NT$1,434

NT$1,822 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.

A spacious living area with a sofa, ottoman, and a large potted plant.

A multi-story hotel with a central atrium, a parking lot, and surrounding greenery.

A hotel lobby with a curved reception desk, a seating area with a sofa and chairs, and a hallway leading to other rooms.

13. Drury Inn & Suites Near La Cantera Parkway

La Cantera District, 9 km from South Texas Medical Center

Eduardo

NT$2,995

NT$3,540 total

includes taxes & fees

Oct 13 - Oct 14

A covered outdoor seating area with lounge chairs and umbrellas, a pool in the background, and potted plants.

A spacious living area with a large sectional sofa, multiple coffee tables, and a wooden partition.

A bar area with a granite countertop, multiple bar stools, and hanging pendant lights.

A modern office space with two desks, chairs, and a large window.

14. Embassy Suites by Hilton San Antonio Landmark

La Cantera District, 8.7 km from South Texas Medical Center

Lenita

NT$5,617

NT$6,640 total

includes taxes & fees

Nov 1 - Nov 2

A Holiday Inn Express reception desk with a modern design, featuring a large illuminated sign, a reception area, and a potted plant.

A conference room with a long table, multiple chairs, and large windows offering a view of greenery and buildings.

A hotel room with a brick wall, a wooden headboard, two beds with white bedding, a bedside table with a lamp, and a wall-mounted light fixture.

A Holiday Inn Express building with a modern design, large windows, and a covered entrance area.

15. Holiday Inn Express San Antonio-Airport by IHG

9.2 km from South Texas Medical Center

Liz

NT$3,473

NT$4,105 total

includes taxes & fees

Oct 11 - Oct 12

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

A reception desk with a computer, framed pictures on the wall, and pendant lighting.

A modern hotel lobby with a reception desk, a coffee station, and a seating area.

An outdoor patio with a pergola, pool, and outdoor seating area.

16. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown Central, 9.5 km from South Texas Medical Center

Amy

NT$2,519

NT$2,977 total

includes taxes & fees

Nov 5 - Nov 6

A modern hotel with a prominent sign reading "LA QUINTA".

A modern lounge area with wooden and colorful seating, a round table, and a flat-screen TV on the wall.

A modern bar area with wooden stools and a marble table, surrounded by seating with patterned cushions.

A modern kitchen with a large window, a counter with various appliances, and a view of the parking lot.

17. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

9.1 km from South Texas Medical Center

john

NT$2,925

NT$3,415 total

includes taxes & fees

Oct 11 - Oct 12

A multi-level hotel atrium with a central courtyard, outdoor seating, and a pool.

A spacious bar area with a long counter, multiple stools, and a television screen.

A building with a large arched doorway, a balcony with a railing, and a tree with green foliage in the foreground.

18. Estancia del Norte San Antonio, Tapestry Collection by Hilton

8.7 km from South Texas Medical Center

Adamaris

NT$4,154

NT$4,910 total

includes taxes & fees

Oct 12 - Oct 13

A modern kitchen with a large flat-screen TV, a glass display case with wine glasses, and a breakfast buffet sign.

A modern kitchen with a large island, bar stools, and a television displaying a football game.

A modern living room with a sofa, two armchairs, a coffee table, and a TV.

An outdoor patio area with seating, a pool, and string lights.

19. Staybridge Suites San Antonio Lackland AFB Area by IHG

Far West Side, 9.8 km from South Texas Medical Center

Denise

NT$4,429

NT$5,170 total

includes taxes & fees

Oct 25 - Oct 26

A modern bar area with seating and a staircase leading to an upper level.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

A modern building with "EMBASSY SUITES" signage, featuring a prominent entrance and landscaped surroundings.

A spacious indoor dining area with multiple tables and chairs, a high ceiling with recessed lighting, and a view of the restaurant kitchen through a glass partition.

20. Embassy Suites by Hilton San Antonio Airport

Uptown Central, 9.6 km from South Texas Medical Center

Arianna

NT$3,919

NT$4,633 total

includes taxes & fees

Oct 11 - Oct 12

View all properties

Compare popular hotels close to South Texas Medical Center

Property	Property class	Guest rating
Drury Inn & Suites San Antonio Northwest Medical Center	9.2 Wonderful 1,479 reviews	View
Fairfield Inn & Suites by Marriott San Antonio Medical Center	9.0 Wonderful 1,093 reviews	View
Courtyard by Marriott Medical Center San Antonio	8.8 Excellent 1,009 reviews	View
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW	8.4 Very good 3,709 reviews	View
The Westin San Antonio North	8.4 Very good 1,650 reviews	View

Top South Texas Medical Center Hotel Reviews

The Westin San Antonio North

8/10 Good

"The hotel was fine for what I needed - somewhere decent to stay for one night. It was not the level of quality or amenities that I would normally expect from a Westin - mostly just very dated. Area and parking lot seemed safe, which was nice."

Courtyard by Marriott Medical Center San Antonio

8/10 Good

"."

Fairfield Inn & Suites by Marriott San Antonio Medical Center

10/10 Excellent

"The room was clean and so was the facility!"

Hyatt Place San Antonio-Northwest/Medical Center

10/10 Excellent

"Buen servicio siempre! Es la 3a vez que vamos ahi"

Atria Inn & Suites

10/10 Excellent

"It’s. Nice place to stay, it’s big and comfortable."

Drury Inn & Suites San Antonio Northwest Medical Center

8/10 Good

"Good location food breakfast could have a little more variety."

Motel 6 San Antonio, TX - Northwest Medical Center

10/10 Excellent

"Clean room"

Sonesta ES Suites San Antonio Northwest - Medical Center

10/10 Excellent

"🙌"

Park Inn by Radisson, Medical Center

10/10 Excellent

"Rooms were clean"

Frequently asked questions

What's the area like around South Texas Medical Center?

South Texas Medical Center is located in a walkable area of San Antonio known for its beautiful river views and biking. If you're looking for a convenient place to stay, check out the 35 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to South Texas Medical Center?

Fairfield Inn & Suites by Marriott San Antonio Medical Center is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located just a short 0.6 mi (1 km) from South Texas Medical Center. Other good options close by include Courtyard by Marriott Medical Center San Antonio and Park Inn by Radisson, Medical Center.

How many hotels will I find close to South Texas Medical Center?

Expedia has 35 hotels and other accommodations within a mile from South Texas Medical Center.

If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best options available near South Texas Medical Center.

Where can I learn more about changing or cancelling my trip in the area near South Texas Medical Center?

For more information about picking new dates or cancelling your stay near South Texas Medical Center, head over to our customer service page.

What can I see and do near South Texas Medical Center?

You can watch performances at Woodlawn Theater, Sheldon Vexler Theatre, and Laugh Out Loud Comedy Club if you're interested in local theater. Create some family memories at Crystal Ice Palace and Monster Mini Golf. Looking for a little shopping break? A trip to Wonderland of the Americas Mall, Huebner Oaks, and Ingram Park Mall might be just the ticket while you're in the area around South Texas Medical Center.

Find hotels near South Texas Medical Center, San Antonio from NT$1,657

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for South Texas Medical Center hotels

1. Drury Inn & Suites San Antonio Northwest Medical Center

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

3. Courtyard by Marriott Medical Center San Antonio

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

5. The Westin San Antonio North

6. Atria Inn & Suites

7. Studio 6 San Antonio, Tx - Northwest Medical Center

8. Park Inn by Radisson, Medical Center

9. OYO Inn & Suites Medical Center San Antonio

10. Motel 6 San Antonio, TX - Fiesta Trails

11. Flex Studios

12. Motel 6 San Antonio, TX - Northwest Medical Center

13. Drury Inn & Suites Near La Cantera Parkway

14. Embassy Suites by Hilton San Antonio Landmark

15. Holiday Inn Express San Antonio-Airport by IHG

16. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

17. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

18. Estancia del Norte San Antonio, Tapestry Collection by Hilton

19. Staybridge Suites San Antonio Lackland AFB Area by IHG

20. Embassy Suites by Hilton San Antonio Airport

Compare popular hotels close to South Texas Medical Center

Top South Texas Medical Center Hotel Reviews

The Westin San Antonio North

Courtyard by Marriott Medical Center San Antonio

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Hyatt Place San Antonio-Northwest/Medical Center

Atria Inn & Suites

Drury Inn & Suites San Antonio Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Sonesta ES Suites San Antonio Northwest - Medical Center

Park Inn by Radisson, Medical Center

Frequently asked questions

Explore a world of travel with Expedia