Find Boutique Hotels in South Carolina Midlands, SC

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Check availability on South Carolina Midlands Boutique Hotels

Tonight
Dec 5 - Dec 6
Tomorrow
Dec 6 - Dec 7
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Top South Carolina Midlands Boutique Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in South Carolina Midlands

Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

2.5 star property
Latta
9.4 out of 10, Exceptional, (529)
"Clean and beautiful, very friendly staff "
United States
claudia
The price is NT$3,106
NT$3,385 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express & Suites Latta by IHG
Lobby
Tru By Hilton Santee

Tru By Hilton Santee

2.5 star property
Santee
9.2 out of 10, Wonderful, (624)
"Nice place to stay"
Canada
Tanya
The price is NT$2,981
NT$3,308 total
includes taxes & fees
Dec 14 - Dec 15
Tru By Hilton Santee
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1158)
"Enjoyed our stay there. "
United States
Cathy
The price is NT$3,087
NT$3,457 total
includes taxes & fees
Dec 7 - Dec 8
Comfort Inn & Suites Florence Center Area
Exterior
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 star property
Cayce
8.2 out of 10, Very Good, (1001)
"We enjoyed our stay. The room was clean and the staff were wonderful!"
United States
Marilyn
The price is NT$2,848
NT$3,161 total
includes taxes & fees
Jan 4 - 2026/1/5
Country Inn & Suites by Radisson, Columbia Airport, SC
Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
9.8 out of 10, Exceptional, (1001)
"Very welcoming, hotel has a clean and friendly presentation."
Canada
VALERIE AND JOHN
The price is NT$3,788
NT$4,205 total
includes taxes & fees
Dec 14 - Dec 15
Fairfield Inn & Suites by Marriott Santee
Lobby
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1002)
"Staff are great, room is clean and amenities very amusing "
United States
Salah
The price is NT$3,231
NT$3,587 total
includes taxes & fees
Dec 30 - Dec 31
Tru by Hilton Orangeburg
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1406)
"The best stay"
United States
Terez
The price is NT$2,348
NT$2,606 total
includes taxes & fees
Dec 8 - Dec 9
Baymont by Wyndham Santee
Property amenity
Lexington Expo Hotel by IHG

Lexington Expo Hotel by IHG

3.0 star property
Lexington
9.2 out of 10, Wonderful, (1000)
"Room was great staff was great"
United States
Stephen
The price is NT$2,730
NT$3,030 total
includes taxes & fees
Dec 9 - Dec 10
Lexington Expo Hotel by IHG
Front of property - evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property
Florence
8.8 out of 10, Excellent, (1001)
"Great stay"
United States
Michaelle
The price is NT$3,131
NT$3,507 total
includes taxes & fees
Jan 5 - 2026/1/6
Hyatt Place Florence Downtown
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property
Florence
9.0 out of 10, Wonderful, (2190)
"Breakfast was great, room very clean ."
United States
Leann
The price is NT$2,944
NT$3,297 total
includes taxes & fees
Dec 7 - Dec 8
Park Inn by Radisson Florence, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South Carolina Midlands Hotel Reviews

Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

10/10 Excellent
"Every staff member was friendly and helpful. There are lots of cool old charm features from the original property."
Marcus 3-night trip
Posted 5 days ago
Graduate by Hilton Columbia SC

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