Find Boutique Hotels in Siesta Isle, FL

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Siesta Isle Boutique Hotels

Next weekend
In two weeks

Top Siesta Isle Boutique Hotels

Top Siesta Isle Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's there to see and do in Siesta Isle?
Once you've decided where you'd like to stay, plan what to do for fun on your vacation. Activities and attractions to experience around Siesta Isle include Key West Express, San Carlos Bay - Bunche Beach Preserve, and Bunche Beach. For even more to see and do, make a stop at Jungle Golf Ft. Myers, Bowditch Point Park, and Lynn Hall Memorial Park.