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Feb 4 - Feb 5
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Where to stay in Serra Highlands

Find the best Serra Highlands areas and neighborhoods for the activities you enjoy most.
Union Square San Francisco a shop-aholic dream; Shutterstock ID 3603152

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco featuring railway items

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman\'s Wharf which includes street scenes as well as a small group of people

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market featuring skyline, a city and city views

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill featuring street scenes

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Serra Highlands Hotel Reviews

Handlery Union Square Hotel

Handlery Union Square Hotel

10/10 Excellent
"Front desk staff were great and the concierge, Judy was very helpful and informative."
Faron 1-night trip
Posted 2 days ago
Handlery Union Square Hotel

Frequently asked questions

What is Serra Highlands like?
Travelers to South San Francisco's Serra Highlands neighborhood will be sure to enjoy a stay in this neighborhood.
How many hotels will I find in the Serra Highlands area?
Book one of Expedia's 5 hotels and other accommodations in Serra Highlands and start exploring everything South San Francisco has to offer.
If I need to cancel my hotel reservation in Serra Highlands, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to get top deals in Serra Highlands.
Where can I learn more about changing or cancelling my trip to Serra Highlands?
For more details about picking new dates or cancelling your trip to Serra Highlands, click here.
What is there to do in this South San Francisco neighborhood?
Cypress Lawn Memorial Park, Hills of Eternity Memorial Park, and Wyatt Earp's Grave are just a few of the places to visit in and around Serra Highlands. While you're out sightseeing, Pet's Rest Cemetery and Serramonte Center are a couple of additional sights to visit in South San Francisco.

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