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Aug 16 - Aug 17
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Aug 17 - Aug 18
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Our top choices for Santo Spirito Hospital hotels

Property entrance
Superior Double Room | 1 bedroom, premium bedding, minibar, in-room safe
Hallway
Superior Double Room | 1 bedroom, premium bedding, minibar, in-room safe

1. San Pietro Boutique Rooms

San Pietro Boutique Rooms
Prati, 0.6 km from Santo Spirito Hospital
United States
Sade
NT$4,717
NT$5,560 total
includes taxes & fees
Aug 22 - Aug 23
San Pietro Boutique Rooms
Front of property
Property entrance
Apartment | Living area
Apartment | 1 bedroom, WiFi (free), bed sheets

2. Home and More St. Angelo APT 5

Home and More St. Angelo APT 5
Prati, 0.6 km from Santo Spirito Hospital
United States
David
NT$2,430
NT$6,176 total
includes taxes & fees
Aug 30 - Aug 31
Home and More St. Angelo APT 5
Front of property
Exclusive Condo | Private kitchen | Electric kettle
Junior Suite | In-room safe, desk, blackout drapes, iron/ironing board (on request)
Exclusive Condo | Living area

3. Passepartout

Passepartout
Parione, 0.6 km from Santo Spirito Hospital
United States
Bhupender
NT$3,944
NT$4,709 total
includes taxes & fees
Aug 24 - Aug 25
Passepartout
Property entrance
Deluxe Triple Room | Desk, laptop workspace, soundproofing, WiFi (free)
Building design
Junior Suite | Desk, laptop workspace, soundproofing, WiFi (free)

4. Porta Castello Suites

Porta Castello Suites
0.5 km from Santo Spirito Hospital
Australia
Sarah
NT$3,787
NT$4,684 total
includes taxes & fees
Aug 24 - Aug 25
Porta Castello Suites
Courtyard
Exclusive House, 3 Bedrooms, Hot Tub, City View (Indipendent Historical Building) | Egyptian cotton sheets, premium bedding, down comforters
Luxury Apartment, 2 Bedrooms, Ensuite, City View (Giulia) | Private kitchen | Coffee/tea maker, full-size fridge, microwave, stovetop
Family Apartment, 1 Bedroom, Courtyard Area | Egyptian cotton sheets, premium bedding, down comforters

5. Your Suite Rome

Your Suite Rome
Regola, 0.6 km from Santo Spirito Hospital
United States
Diana
NT$6,591
NT$11,476 total
includes taxes & fees
Aug 18 - Aug 19
Your Suite Rome
Exterior
Courtyard
Reception
Lobby sitting area

6. Le Suite Del Barone

Le Suite Del Barone
Ponte, 0.6 km from Santo Spirito Hospital
United States
Mary
NT$4,960
NT$5,975 total
includes taxes & fees
Aug 25 - Aug 26
Le Suite Del Barone
Exterior
Exterior
Superior Apartment | Blackout drapes, iron/ironing board, WiFi (free)
Superior Apartment | Blackout drapes, iron/ironing board, WiFi (free)

7. Palazzo Taverna Apartments

Palazzo Taverna Apartments
Ponte, 0.5 km from Santo Spirito Hospital
United States
Ghassan
NT$8,491
NT$10,897 total
includes taxes & fees
Aug 18 - Aug 19
Palazzo Taverna Apartments
View from room
Property entrance
View from room
Lobby sitting area

8. Charme 308

Charme 308
Ponte, 0.3 km from Santo Spirito Hospital
Canada
Elizabeth
NT$3,801
NT$4,700 total
includes taxes & fees
Aug 20 - Aug 21
Charme 308
Front of property
1 bedroom, premium bedding, memory foam beds, minibar
Daily local cuisine breakfast for a fee
Superior Room | Bathroom | Shower, eco-friendly toiletries, hair dryer, bidet

9. Velantia Vaticano - Guesthouse

Velantia Vaticano - Guesthouse
Prati, 0.6 km from Santo Spirito Hospital
Australia
Claudette
NT$3,868
NT$4,774 total
includes taxes & fees
Aug 17 - Aug 18
Velantia Vaticano - Guesthouse
Reception
Reception
Standard Double Room | Premium bedding, minibar (free items), in-room safe, desk
View from property

10. Corso Vittorio 308

Corso Vittorio 308
Ponte, 0.3 km from Santo Spirito Hospital
United States
Laurie
NT$5,078
NT$6,104 total
includes taxes & fees
Aug 18 - Aug 19
Corso Vittorio 308
Front of property
Reception
Garden
Classic Quadruple Room | Hypo-allergenic bedding available, minibar, in-room safe, desk

11. Hotel Sant' Anna

Hotel Sant' Anna
0.5 km from Santo Spirito Hospital
United States
John
NT$6,309
NT$7,385 total
includes taxes & fees
Aug 23 - Aug 24
Hotel Sant' Anna
Front of property
Triple Room | Select Comfort beds, in-room safe, desk, blackout drapes
Triple Room | Select Comfort beds, in-room safe, desk, blackout drapes
Property grounds

12. B&B At Your Place

B&B At Your Place
0.4 km from Santo Spirito Hospital
United States
Joshua
NT$2,636
NT$3,345 total
includes taxes & fees
Aug 24 - Aug 25
B&B At Your Place
Exterior
Espresso maker, mini-fridge, stovetop, dishwasher
Reception
Reception

13. Now Apartments

Now Apartments
Ponte, 0.6 km from Santo Spirito Hospital
Canada
Darren
NT$6,823
NT$7,950 total
includes taxes & fees
Aug 25 - Aug 26
Now Apartments
Deluxe Quadruple Room, 1 Bedroom, Refrigerator | 1 bedroom, premium bedding, in-room safe, desk
Interior entrance
Mini-refrigerator
Property entrance

14. Capricci Romani

Capricci Romani
0.4 km from Santo Spirito Hospital
United States
Troy
NT$2,523
NT$3,146 total
includes taxes & fees
Aug 21 - Aug 22
Capricci Romani
Reception
Luxury Suite | Minibar, in-room safe, desk, blackout drapes
Reception
LCD TV

15. Boutique Hotel Piedra Rome City Centre

Boutique Hotel Piedra Rome City Centre
Prati, 0.5 km from Santo Spirito Hospital
United States
Edgar
NT$4,203
NT$5,068 total
includes taxes & fees
Aug 18 - Aug 19
Boutique Hotel Piedra Rome City Centre
Premium bedding, memory foam beds, minibar, in-room safe
Premium bedding, memory foam beds, minibar, in-room safe
In-room dining
Aerial view

16. Vatican Style

Vatican Style
0.5 km from Santo Spirito Hospital
United States
Troy
NT$3,758
NT$4,505 total
includes taxes & fees
Aug 17 - Aug 18
Vatican Style
Superior Double Room, 1 Double Bed | View from room
Property entrance
Reception
Courtyard

17. La Maison dell'Orologio

La Maison dell'Orologio
Ponte, 0.4 km from Santo Spirito Hospital
United States
Karolyn
NT$3,575
NT$4,378 total
includes taxes & fees
Aug 22 - Aug 23
La Maison dell'Orologio
Suite | Premium bedding, down comforters, in-room safe, desk
Business center
Reception
View from room

18. The Pope's Window

The Pope's Window
0.6 km from Santo Spirito Hospital
Canada
Jessica C
NT$4,647
NT$5,557 total
includes taxes & fees
Aug 27 - Aug 28
The Pope's Window
Suite, Jetted Tub (Breakfast at Navona Street Hotel) | Minibar, in-room safe, desk, laptop workspace
Reception
Coffee service
Suite, Jetted Tub (Breakfast at Navona Street Hotel) | Minibar, in-room safe, desk, laptop workspace

19. B&B Rome River Inn

B&B Rome River Inn
Ponte, 0.4 km from Santo Spirito Hospital
United States
Paula D.
NT$5,248
NT$6,218 total
includes taxes & fees
Aug 27 - Aug 28
B&B Rome River Inn
Exterior
Junior Quadruple Room | In-room safe, desk, blackout drapes, soundproofing
Reception
Reception

20. VATICANO LUXURY GUEST HOUSE

VATICANO LUXURY GUEST HOUSE
Prati, 0.5 km from Santo Spirito Hospital
Mexico
luis
NT$2,571
NT$3,347 total
includes taxes & fees
Aug 28 - Aug 29
VATICANO LUXURY GUEST HOUSE
View all properties

Top Santo Spirito Hospital Hotel Reviews

Hotel Abruzzi

Hotel Abruzzi

10/10 Excellent
"amazing location"
Deepika 2-night trip
Posted 16 hours ago
Hotel Abruzzi
Vatican Style

Vatican Style

8/10 Good
"Had several issues with the Air Conditioning unit, however it was addressed immediately by the staff and fixed. It was also during the City’s heatwave."
Andre 3-night trip
Posted 20 hours ago
Vatican Style
Hotel Nazionale

Hotel Nazionale

10/10 Excellent
"Hotel is very charming and have great location, walking distance to most attractions."
Ajsa 2-night trip
Posted 21 hours ago
Hotel Nazionale
Hotel Smeraldo

Hotel Smeraldo

10/10 Excellent
"Very friendly front desk, optimal location!"
Julia 2-night trip
Posted 2 days ago
Hotel Smeraldo
Starhotels Michelangelo

Starhotels Michelangelo

10/10 Excellent
"Room was very clean and staff was super helpful"
Nicole 2-night trip
Posted 2 days ago
Starhotels Michelangelo
Trianon Borgo Pio

Trianon Borgo Pio

10/10 Excellent
"This was a beautiful hotel with a perfect room for me, my husband and our 2 teenagers. The bathroom was beautiful and the apartment set up was perfect. Breakfast on the rooftop was delicious and also beautiful. Having a laundry in the building was also a positive since we were on a longer trip. Directly behind the hotel is a street with quaint restaurants, Gelato shops, and shops. It was also easy to get an Uber to the Colosseum and we had no problem walking to the Vatican. Excellent stay and would recommend to all of our friends and family"
Amy 2-night trip
Posted 2 days ago
Trianon Borgo Pio
Grand Hotel Olympic

Grand Hotel Olympic

8/10 Good
"The room was clean and cool, which was a much needed thing in August. Breakfast had a good range of foods and drinks. The TV didn’t work - but that didn’t bother us as we were so busy and well placed to get around. It’s literally 5 minutes from the Vatican and Metro A Line. So many good restaurants nearby too. We would stay here again 100%."
Ella Victoria 7-night trip
Posted 7 days ago
Grand Hotel Olympic
Hotel Adriatic

Hotel Adriatic

10/10 Excellent
"Very nice people, would stay again!"
Elle 1-night trip
Posted 12 days ago
Hotel Adriatic

Frequently asked questions

What's the area like around Santo Spirito Hospital?
Santo Spirito Hospital is located in a historic area of Rome known for its stunning cathedral and notable monuments. If you're looking for a convenient place to stay, check out the 2025 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Santo Spirito Hospital?
Adjacent to Santo Spirito Hospital, Villa Agrippina Gran Meliá - The Leading Hotels of the World is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good options close by include Grand Hotel Olympic and Hotel Abruzzi.
How many hotels will I be able to find close to Santo Spirito Hospital?
Expedia has 2025 hotels and other accommodations within a mile from Santo Spirito Hospital.
If I need to cancel the hotel reservation for my stay near Santo Spirito Hospital, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to get top deals close to Santo Spirito Hospital.
Where can I learn more about changing or cancelling my trip in the area near Santo Spirito Hospital?
For more information about changing or cancelling your stay near Santo Spirito Hospital, head over to our customer service page.
What can I see and do near Santo Spirito Hospital?
You might want to spend some time browsing the exhibits at Vatican Museums, Castel Sant'Angelo, or Cloister of Bramante. St. Peter's Basilica, Piazza Navona, and Pantheon are well-known local landmarks worth a visit. You can check out the local talent at Paul VI Audience Hall, Teatro de'Servi Roma, and Teatro dell'Opera di Roma.
How can I get to Santo Spirito Hospital?
With so many choices for transportation, seeing all of the area near Santo Spirito Hospital is simple. You can access metro transit at Venezia Tram Stop, Arenula-Cairoli Tram Station, and Barberini Station. If you'd like to explore more of the area, hop aboard a train from Rome Piazzale Flaminio Station, Rome Termini Station, or Rome (XRJ-Termini Rail Station).