Santa Cruz Vacations
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Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Equipetrol
Though Equipetrol might not have many top sights, you can venture to the surrounding area to see attractions like Santa Cruz Zoo and Municipal Library.
Centro Histórico
3 out of top 10 points of interest in this area
If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.
Hamacas
While Hamacas isn't home to many top sights, Las Brisas Shopping Center and Santa Cruz Zoo are some notable places to visit nearby.
Zona Sur (South Zone)
Zona Sur (South Zone) might not have many top sights, but Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre are two attractions nearby that you can check out.
Urubó
While Urubó might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Guembe Biocenter and Ventura Mall.
Find the Best Santa Cruz Vacation Packages
Santa Cruz Hotel Deals
Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
NT$1,267
NT$1,267 total
Oct 26 - Oct 27
9.4/10 Exceptional! (153 reviews)
"The hotel is OK, but nothing more. Stuff was unpleasant"
Reviewed on 2026/9/24
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455 Santa Cruz
NT$4,315
NT$4,315 total
Nov 7 - Nov 8
Marriott Santa Cruz de la Sierra Hotel
4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
NT$3,377
NT$3,377 total
Nov 1 - Nov 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Cruz attractions
Plaza 24 de Septiembre
8.8/10 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
San Lorenzo Cathedral
9.0/10 (84 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
Ventura Mall
9.0/10 (183 reviews)
Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.
Guembe Biocenter
8.8/10 (60 reviews)
This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.
Ramon Tahuichi Aguilera Stadium
8.4/10 (18 reviews)
This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernized facilities and vibrant Santa Cruz culture.
Las Brisas Shopping Center
8.4/10 (40 reviews)
This modern complex offers 80+ stores, a nine-screen cinema, and a unique outdoor restaurant promenade. Explore the gastronomic boulevard for dining experiences beyond the standard food court options.
Santa Cruz Zoo
8.4/10 (53 reviews)
The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.
Blacutt Square
8.2/10 (19 reviews)
Plaza Blacutt offers a verdant escape in Santa Cruz with mature trees shading tiled pathways. Enjoy local flavors from vendors along the northern edge while children play in the well-equipped playground areas.
Frequently asked questions
How much does a Santa Cruz vacation package cost?
You'll find cheap prices on Expedia for your Santa Cruz break. However, a range of factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
February, April and May are the best times to look for cheap Santa Cruz vacation packages. Opting to travel in quieter months means you can typically find lower prices on hotels and flights.
How many days is enough for Santa Cruz?
Typically, a handful of days is enough to tick off the main sights during your Santa Cruz vacation. However, if you prefer to have some time to kick back or take day tours, think about extending your itinerary.
Is it worth booking a vacation package to Santa Cruz?
Santa Cruz is a good vacation destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're traveling with the family or getting away with friends, a Santa Cruz vacation promises a good time for everyone.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some tempting Santa Cruz package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or look for Santa Cruz package deals in the off-peak season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your vacation package as early as possible.
Is it cheaper to book a Santa Cruz vacation as a package?
You can enjoy significant savings on your Santa Cruz escape by booking a personalized vacation package. Click on the "Package" heading, then enter your travel dates and destination to browse some great hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Santa Cruz?
If you're considering an impromptu Santa Cruz adventure, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can find sensational deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Cruz?
- Choose your dates: What you want to do in Santa Cruz and your favorite season will help you decide when to get away.
- Work out your budget: Make sure you have enough money to pay for everything from transportation and dining out to experiences and flights. Your hotel will probably be the biggest expense during your trip to Santa Cruz.
- Work out your trip length: Consider how much time you want to spend discovering Santa Cruz. Plan your days so you can get to all the experiences and attractions you're interested in without rushing.
- Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left is to choose a Santa Cruz vacation package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
