South America Vacations & Trips

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Top destinations in South America

A historic building with ornate architecture and a large entrance.

São Paulo

São Paulo
A cityscape with historic buildings, a prominent clock tower, and modern skyscrapers under a clear blue sky.

Buenos Aires

Buenos Aires
A multi-tiered waterfall surrounded by lush greenery.

Foz do Iguaçu

Foz do Iguaçu
A panoramic view of Rio de Janeiro at sunset, featuring the Christ the Redeemer statue, Sugarloaf Mountain, Guanabara Bay, and the cityscape with cable cars.

Rio de Janeiro

Rio de Janeiro
A narrow street lined with colorful buildings, featuring balconies and potted plants.

Cartagena

Cartagena
A plaza with a large building featuring a dome and spires, surrounded by trees and people.

Medellín

Medellín
A village with traditional architecture, surrounded by lush green mountains and a prominent church.

Bogotá

Bogotá

South America Hotel Deals

Rochester Classic

Rochester Classic

Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
NT$1,844
NT$1,939 total
Sep 28 - Sep 29
7.8/10 Good! (426 reviews)
"The property is clean, and very well located for dinning, shopping, cultural life, touristic attractions. It is very important to know, if you decide to rent a car, that the property has NO PARKING available and there is NO STREET PARKING AROUND! There are several parking garages around but they ..."

Reviewed on 2026/9/12

Rochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
NT$4,816
NT$4,911 total
Oct 1 - Oct 2
9/10 Wonderful! (1,001 reviews)
"Deben de revisar todos los dispositivos electrónicos. Y un mejor acompañamiento de las amenidades del hotel"

Reviewed on 2026/9/6

Regal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

25 De Mayo 630 Buenos Aires Capital Federal
6.6/10 (300 reviews)
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."

Reviewed on 2018/3/6

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Concorde Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I travel to South America right now?
Find info about South America travel restrictions, quarantine policies and much more by going to our Covid-19 Travel Advisor.
If I'm not able to travel, can I cancel my South America vacation package?
Don't stress if you're rethinking your South America vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur a fee from your hotel, airline or car rental company. We totally understand life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.
When is the best time of year to visit South America?
Anytime is an excellent time of the year to take a break in South America, but generally you'll land the best deals in . Prices increase in , so expect to pay more for your flights and hotel. Love sightseeing but don't like lining up for attractions? Organize your South America escape for . Typically, it's a lot quieter than in .
What should I do on vacation in South America?
From exciting attractions to hidden treasures, there's lots to do in South America. To help you plan your time in this amazing location, here are some of the most sought-after tours and activities:
How far in advance should I book my South America vacation?
While not all airlines advertise tickets early, it's usually possible to start comparing international fares on Expedia up to 12 months in advance. This is the time when you'll bag some fantastic bargains. If you're booking late, there's a chance you could get lucky. Sometimes the lowest prices emerge only weeks before departure.
What should I know before booking a South America travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, bundle your flights, hotels and rental cars and save a pretty penny. Whatever your vacation goals are, you'll find a package to suit your budget.

Stay near popular South America attractions

A beach with a road running parallel to it, palm trees, and buildings in the background.

Copacabana Beach

9.0/10 (5,319 reviews)
More than just a stretch of sand, Rio de Janeiro’s most famous beach is where locals and visitors from all over the world come to relax, strut, pose and play.
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A city street with tall modern buildings, palm trees, and a busy traffic scene.

Paulista Avenue

9.0/10 (2,555 reviews)
See the financial and cultural heart of one of South America’s busiest cities before unwinding in a bar full of local business people at the end of the day.
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An aerial view of a city with a large racetrack surrounded by residential and commercial buildings.

Interlagos Race Track

8.4/10 (385 reviews)
Interlagos Race Track is one of the more well-known attractions to visit during your trip to São Paulo. Experience the art scene and museums in this culturally rich area.
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An aerial view of a theme park with roller coasters, a stadium, and surrounding greenery.

Beto Carrero World

9.2/10 (157 reviews)
Enjoy the rides and games at Beto Carrero World and see why people love this theme park in Penha. Stroll along the beaches or experience the area's theater scene.
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A large church with a prominent clock tower and a dome, surrounded by lush greenery and a curved bridge.

Basilica of the National Shrine of Our Lady of Aparecida

9.8/10 (157 reviews)
Find out about the history of Basilica of the National Shrine of Our Lady of Aparecida, one of the top monuments in Aparecida. Stroll along the riverfront or discover the area's countryside.
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A large waterfall with multiple tiers, surrounded by lush greenery and a viewing platform with people observing.

Iguazu Falls

9.8/10 (1,734 reviews)
Follow trails around a wildlife-rich national park to discover a spectacular natural wonder consisting of some 275 waterfalls, including the thunderous Devil’s Throat.
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A beach with palm trees, ocean waves, and mountains in the background.

Ipanema Beach

9.2/10 (1,627 reviews)
See the place that inspired a famous song about a bikini at this upscale beach.
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A beach with turquoise water, a boat, and a clear sky.

Pajucara Beach

8.6/10 (205 reviews)
Take a boat to a natural shallow pool and cycle along the promenade in this busy beach area of bars and restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.